Title : Development of multifunctional fluorescence-emitting potential theranostic agents for Alzheimer's disease - Bajad_2025_Talanta_287_127574 |
Author(s) : Bajad NG , T AG , Kothari M , Mukherjee R , Chowdhury A , Kumar A , Krishnamurthy S , Singh SK |
Ref : Talanta , 287 :127574 , 2025 |
Abstract : |
PubMedSearch : Bajad_2025_Talanta_287_127574 |
PubMedID: 39818048 |
Title : Development of Donor-Acceptor Architecture-Based Potential Theranostic Fluorescent Probes for Alzheimer's Disease - Bajad_2025_ACS.Chem.Neurosci__ |
Author(s) : Bajad NG , A GT , Sharma K , Tapadia MG , Kumar A , Krishnamurthy S , Singh SK |
Ref : ACS Chem Neurosci , : , 2025 |
Abstract : |
PubMedSearch : Bajad_2025_ACS.Chem.Neurosci__ |
PubMedID: 40107858 |
Title : Discovery of pyrazoline analogs as multi-targeting cholinesterase, beta-secretase and Abeta aggregation inhibitors through lead optimization strategy - Bajad_2025_Int.J.Biol.Macromol_301_140436 |
Author(s) : Bajad NG , Jangra J , T AG , Kumar A , Krishnamurthy S , Singh SK |
Ref : Int J Biol Macromol , 301 :140436 , 2025 |
Abstract : |
PubMedSearch : Bajad_2025_Int.J.Biol.Macromol_301_140436 |
PubMedID: 39884636 |
Title : Design, Synthesis, and Biological Investigation of Quinazoline Derivatives as Multitargeting Therapeutics in Alzheimer's Disease Therapy - Verma_2024_ACS.Chem.Neurosci__ |
Author(s) : Verma A , Waiker DK , Singh N , Roy A , Saraf P , Bhardwaj B , Krishnamurthy S , Trigun SK , Shrivastava SK |
Ref : ACS Chem Neurosci , : , 2024 |
Abstract : |
PubMedSearch : Verma_2024_ACS.Chem.Neurosci__ |
PubMedID: 38327209 |
Title : Design, synthesis, and biological evaluation of some 2-(3-oxo-5,6-diphenyl-1,2,4-triazin-2(3H)-yl)-N-phenylacetamide hybrids as MTDLs for Alzheimer's disease therapy - Waiker_2024_Eur.J.Med.Chem_271_116409 |
Author(s) : Waiker DK , Verma A , Gajendra TA , Namrata , Roy A , Kumar P , Trigun SK , Srikrishna S , Krishnamurthy S , Davisson VJ , Shrivastava SK |
Ref : Eur Journal of Medicinal Chemistry , 271 :116409 , 2024 |
Abstract : |
PubMedSearch : Waiker_2024_Eur.J.Med.Chem_271_116409 |
PubMedID: 38663285 |
Title : Lead optimization based design, synthesis, and pharmacological evaluation of quinazoline derivatives as multi-targeting agents for Alzheimer's disease treatment - Verma_2024_Eur.J.Med.Chem_271_116450 |
Author(s) : Verma A , Waiker DK , Singh N , Singh A , Saraf P , Bhardwaj B , Kumar P , Krishnamurthy S , Srikrishna S , Shrivastava SK |
Ref : Eur Journal of Medicinal Chemistry , 271 :116450 , 2024 |
Abstract : |
PubMedSearch : Verma_2024_Eur.J.Med.Chem_271_116450 |
PubMedID: 38701714 |
Title : Development of multi-targetable chalcone derivatives bearing N-aryl piperazine moiety for the treatment of Alzheimer's disease - Bajad_2024_Bioorg.Chem_143_107082 |
Author(s) : Bajad NG , Singh RB , T AG , Gutti G , Kumar A , Krishnamurthy S , Singh SK |
Ref : Bioorg Chem , 143 :107082 , 2024 |
Abstract : |
PubMedSearch : Bajad_2024_Bioorg.Chem_143_107082 |
PubMedID: 38199142 |
Title : Indole-3 Carbinol and Diindolylmethane Mitigated beta-Amyloid-Induced Neurotoxicity and Acetylcholinesterase Enzyme Activity: In Silico, In Vitro, and Network Pharmacology Study - Ramakrishna_2024_Diseases_12_ |
Author(s) : Ramakrishna K , Karuturi P , Siakabinga Q , T AG , Krishnamurthy S , Singh S , Kumari S , Kumar GS , Sobhia ME , Rai SN |
Ref : Diseases , 12 : , 2024 |
Abstract : |
PubMedSearch : Ramakrishna_2024_Diseases_12_ |
PubMedID: 39195183 |
Title : Centella asiatica improves memory and executive function in middle aged rats by controlling oxidative stress and cholinergic transmission - Firdaus_2024_J.Ethnopharmacol__117888 |
Author(s) : Firdaus Z , Gutti G , Ganeshpurkar A , Kumar A , Krishnamurthy S , Singh SK , Singh TD |
Ref : J Ethnopharmacol , :117888 , 2024 |
Abstract : |
PubMedSearch : Firdaus_2024_J.Ethnopharmacol__117888 |
PubMedID: 38336185 |
Title : Discovery of triazole-bridged aryl adamantane analogs as an intriguing class of multifunctional agents for treatment of Alzheimer's disease - Gutti_2023_Eur.J.Med.Chem_259_115670 |
Author(s) : Gutti G , Leifeld J , Kakarla R , Bajad NG , Ganeshpurkar A , Kumar A , Krishnamurthy S , Klein-Schmidt C , Tapken D , Hollmann M , Singh SK |
Ref : Eur Journal of Medicinal Chemistry , 259 :115670 , 2023 |
Abstract : |
PubMedSearch : Gutti_2023_Eur.J.Med.Chem_259_115670 |
PubMedID: 37515920 |
Title : Design, Synthesis, and Biological Evaluation of Piperazine and N-Benzylpiperidine Hybrids of 5-Phenyl-1,3,4-oxadiazol-2-thiol as Potential Multitargeted Ligands for Alzheimer's Disease Therapy - Waiker_2023_ACS.Chem.Neurosci__ |
Author(s) : Waiker DK , Verma A , Akhilesh , Gajendra TA , Singh N , Roy A , Dilnashin H , Tiwari V , Trigun SK , Singh SP , Krishnamurthy S , Lama P , Davisson VJ , Shrivastava SK |
Ref : ACS Chem Neurosci , : , 2023 |
Abstract : |
PubMedSearch : Waiker_2023_ACS.Chem.Neurosci__ |
PubMedID: 37216500 |
Title : Extraction, isolation, synthesis, and biological evaluation of novel piperic acid derivatives for the treatment of Alzheimer's disease - Kumar_2023_Mol.Divers__ |
Author(s) : Kumar J , Shankar G , Kumar S , Thomas J , Singh N , Srikrishna S , Satija J , Krishnamurthy S , Modi G , Mishra SK |
Ref : Mol Divers , : , 2023 |
Abstract : |
PubMedSearch : Kumar_2023_Mol.Divers__ |
PubMedID: 37351693 |
Title : Discovery of multi-target directed 3-OH pyrrolidine derivatives through a semisynthetic approach from alkaloid vasicine for the treatment of Alzheimer's disease - Bhanukiran_2023_Eur.J.Med.Chem_249_115145 |
Author(s) : Bhanukiran K , T AG , Krishnamurthy S , Singh SK , Hemalatha S |
Ref : Eur Journal of Medicinal Chemistry , 249 :115145 , 2023 |
Abstract : |
PubMedSearch : Bhanukiran_2023_Eur.J.Med.Chem_249_115145 |
PubMedID: 36706620 |
Title : Development and Evaluation of Some Molecular Hybrids of N-(1-Benzylpiperidin-4-yl)-2-((5-phenyl-1,3,4-oxadiazol-2-yl)thio) as Multifunctional Agents to Combat Alzheimer's Disease - Waiker_2023_ACS.Omega_8_9394 |
Author(s) : Waiker DK , Verma A , Saraf P , T AG , Krishnamurthy S , Chaurasia RN , Shrivastava SK |
Ref : ACS Omega , 8 :9394 , 2023 |
Abstract : |
PubMedSearch : Waiker_2023_ACS.Omega_8_9394 |
PubMedID: 36936338 |
Title : Effect of sulfonamide derivatives of phenylglycine on scopolamine-induced amnesia in rats - Ganeshpurkar_2023_Ibrain_9_13 |
Author(s) : Ganeshpurkar A , Singh R , Tripathi P , Alam Q , Krishnamurthy S , Kumar A , Singh SK |
Ref : Ibrain , 9 :13 , 2023 |
Abstract : |
PubMedSearch : Ganeshpurkar_2023_Ibrain_9_13 |
PubMedID: 37786521 |
Title : Discovery of new phenyl sulfonyl-pyrimidine carboxylate derivatives as the potential multi-target drugs with effective anti-Alzheimer's action: Design, synthesis, crystal structure and in-vitro biological evaluation - Manzoor_2021_Eur.J.Med.Chem_215_113224 |
Author(s) : Manzoor S , Prajapati SK , Majumdar S , Raza K , Gabr MT , Kumar S , Pal K , Rashid H , Krishnamurthy S , Hoda N |
Ref : Eur Journal of Medicinal Chemistry , 215 :113224 , 2021 |
Abstract : |
PubMedSearch : Manzoor_2021_Eur.J.Med.Chem_215_113224 |
PubMedID: 33582578 |
Title : Neuroprotective effects of quercetin produced by an endophytic fungus Nigrospora oryzae isolated from Tinospora cordifolia - Vig_2021_J.Appl.Microbiol__ |
Author(s) : Vig R , Bhadra F , Gupta SK , Krishnamurthy S , Vasundhara M |
Ref : J Appl Microbiol , : , 2021 |
Abstract : |
PubMedSearch : Vig_2021_J.Appl.Microbiol__ |
PubMedID: 34091993 |
Title : Centella asiatica prevents D-galactose-Induced cognitive deficits, oxidative stress and neurodegeneration in the adult rat brain - Firdaus_2020_Drug.Chem.Toxicol__1 |
Author(s) : Firdaus Z , Singh N , Prajapati SK , Krishnamurthy S , Singh TD |
Ref : Drug & Chemical Toxicology , :1 , 2020 |
Abstract : |
PubMedSearch : Firdaus_2020_Drug.Chem.Toxicol__1 |
PubMedID: 33078641 |
Title : Discovery of novel series of 2-substituted benzo[d]oxazol-5-amine derivatives as multi-target directed ligands for the treatment of Alzheimer's disease - Gutti_2019_Eur.J.Med.Chem_182_111613 |
Author(s) : Gutti G , Kakarla R , Kumar D , Beohar M , Ganeshpurkar A , Kumar A , Krishnamurthy S , Singh SK |
Ref : Eur Journal of Medicinal Chemistry , 182 :111613 , 2019 |
Abstract : |
PubMedSearch : Gutti_2019_Eur.J.Med.Chem_182_111613 |
PubMedID: 31437780 |
Title : Design and development of multitarget-directed N-Benzylpiperidine analogs as potential candidates for the treatment of Alzheimer's disease - Sharma_2019_Eur.J.Med.Chem_167_510 |
Author(s) : Sharma P , Tripathi A , Tripathi PN , Prajapati SK , Seth A , Tripathi MK , Srivastava P , Tiwari V , Krishnamurthy S , Shrivastava SK |
Ref : Eur Journal of Medicinal Chemistry , 167 :510 , 2019 |
Abstract : |
PubMedSearch : Sharma_2019_Eur.J.Med.Chem_167_510 |
PubMedID: 30784883 |
Title : Electrochemical micro analytical device interfaced with portable potentiostat for rapid detection of chlorpyrifos using acetylcholinesterase conjugated metal organic framework using Internet of things - Nagabooshanam_2019_Sci.Rep_9_19862 |
Author(s) : Nagabooshanam S , Roy S , Mathur A , Mukherjee I , Krishnamurthy S , Bharadwaj LM |
Ref : Sci Rep , 9 :19862 , 2019 |
Abstract : |
PubMedSearch : Nagabooshanam_2019_Sci.Rep_9_19862 |
PubMedID: 31882767 |
Title : 4,6-Diphenylpyrimidine Derivatives as Dual Inhibitors of Monoamine Oxidase and Acetylcholinesterase for the Treatment of Alzheimer's Disease - Kumar_2019_ACS.Chem.Neurosci_10_252 |
Author(s) : Kumar B , Dwivedi AR , Sarkar B , Gupta SK , Krishnamurthy S , Mantha AK , Parkash J , Kumar V |
Ref : ACS Chem Neurosci , 10 :252 , 2019 |
Abstract : |
PubMedSearch : Kumar_2019_ACS.Chem.Neurosci_10_252 |
PubMedID: 30296051 |
Title : Multifunctional hybrid sulfonamides as novel therapeutic agents for Alzheimer's disease - Swetha_2019_Future.Med.Chem_11_3161 |
Author(s) : Swetha R , Kumar D , Gupta SK , Ganeshpurkar A , Singh R , Gutti G , Jana S , Krishnamurthy S , Singh SK |
Ref : Future Med Chem , 11 :3161 , 2019 |
Abstract : |
PubMedSearch : Swetha_2019_Future.Med.Chem_11_3161 |
PubMedID: 31838895 |
Title : Development of pyrazole and spiropyrazoline analogs as multifunctional agents for treatment of Alzheimer's disease - Gutti_2019_Bioorg.Chem_90_103080 |
Author(s) : Gutti G , Kumar D , Paliwal P , Ganeshpurkar A , Lahre K , Kumar A , Krishnamurthy S , Singh SK |
Ref : Bioorg Chem , 90 :103080 , 2019 |
Abstract : |
PubMedSearch : Gutti_2019_Bioorg.Chem_90_103080 |
PubMedID: 31271946 |
Title : Design and development of molecular hybrids of 2-pyridylpiperazine and 5-phenyl-1,3,4-oxadiazoles as potential multifunctional agents to treat Alzheimer's disease - Tripathi_2019_Eur.J.Med.Chem_183_111707 |
Author(s) : Tripathi A , Choubey PK , Sharma P , Seth A , Tripathi PN , Tripathi MK , Prajapati SK , Krishnamurthy S , Shrivastava SK |
Ref : Eur Journal of Medicinal Chemistry , 183 :111707 , 2019 |
Abstract : |
PubMedSearch : Tripathi_2019_Eur.J.Med.Chem_183_111707 |
PubMedID: 31561043 |
Title : Design and development of 1,3,4-oxadiazole derivatives as potential inhibitors of acetylcholinesterase to ameliorate scopolamine-induced cognitive dysfunctions - Mishra_2019_Bioorg.Chem_89_103025 |
Author(s) : Mishra P , Sharma P , Tripathi PN , Gupta SK , Srivastava P , Seth A , Tripathi A , Krishnamurthy S , Shrivastava SK |
Ref : Bioorg Chem , 89 :103025 , 2019 |
Abstract : |
PubMedSearch : Mishra_2019_Bioorg.Chem_89_103025 |
PubMedID: 31176239 |
Title : Design, synthesis, and pharmacological evaluation of 2-amino-5-nitrothiazole derived semicarbazones as dual inhibitors of monoamine oxidase and cholinesterase: effect of the size of aryl binding site - Tripathi_2018_J.Enzyme.Inhib.Med.Chem_33_37 |
Author(s) : Tripathi RKP , V MS , Gupta SK , Krishnamurthy S , Ayyannan SR |
Ref : J Enzyme Inhib Med Chem , 33 :37 , 2018 |
Abstract : |
PubMedSearch : Tripathi_2018_J.Enzyme.Inhib.Med.Chem_33_37 |
PubMedID: 29098902 |
Title : Development of Piperazinediones as dual inhibitor for treatment of Alzheimer's disease - Kumar_2018_Eur.J.Med.Chem_150_87 |
Author(s) : Kumar D , Gupta SK , Ganeshpurkar A , Gutti G , Krishnamurthy S , Modi G , Singh SK |
Ref : Eur Journal of Medicinal Chemistry , 150 :87 , 2018 |
Abstract : |
PubMedSearch : Kumar_2018_Eur.J.Med.Chem_150_87 |
PubMedID: 29524731 |
Title : Global Analysis of Palmitoylated Proteins in Toxoplasma gondii - Foe_2015_Cell.Host.Microbe_18_501 |
Author(s) : Foe IT , Child MA , Majmudar JD , Krishnamurthy S , van der Linden WA , Ward GE , Martin BR , Bogyo M |
Ref : Cell Host Microbe , 18 :501 , 2015 |
Abstract : |
PubMedSearch : Foe_2015_Cell.Host.Microbe_18_501 |
PubMedID: 26468752 |
Title : Acitretin-responsive ichthyosis in Chanarin-Dorfman syndrome with a novel mutation in the ABHD5\/CGI-58 gene - Srinivasaraghavan_2014_Pediatr.Dermatol_31_612 |
Author(s) : Srinivasaraghavan R , Krishnamurthy S , Chandar R , Cassandrini D , Mahadevan S , Bruno C , Santorelli FM |
Ref : Pediatr Dermatol , 31 :612 , 2014 |
Abstract : |
PubMedSearch : Srinivasaraghavan_2014_Pediatr.Dermatol_31_612 |
PubMedID: 23756328 |
Gene_locus related to this paper: human-ABHD5 |
Title : Asparagus racemosus competitively inhibits in vitro the acetylcholine and monoamine metabolizing enzymes - Meena_2011_Neurosci.Lett_503_6 |
Author(s) : Meena J , Ojha R , Muruganandam AV , Krishnamurthy S |
Ref : Neuroscience Letters , 503 :6 , 2011 |
Abstract : |
PubMedSearch : Meena_2011_Neurosci.Lett_503_6 |
PubMedID: 21843599 |
Title : Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2 - Nickell_2010_J.Pharmacol.Exp.Ther_332_612 |
Author(s) : Nickell JR , Krishnamurthy S , Norrholm S , Deaciuc G , Siripurapu KB , Zheng G , Crooks PA , Dwoskin LP |
Ref : Journal of Pharmacology & Experimental Therapeutics , 332 :612 , 2010 |
Abstract : |
PubMedSearch : Nickell_2010_J.Pharmacol.Exp.Ther_332_612 |
PubMedID: 19855096 |
Title : Asparagus recemosus enhances memory and protects against amnesia in rodent models - Ojha_2010_Brain.Cogn_74_1 |
Author(s) : Ojha R , Sahu AN , Muruganandam AV , Singh GK , Krishnamurthy S |
Ref : Brain Cogn , 74 :1 , 2010 |
Abstract : |
PubMedSearch : Ojha_2010_Brain.Cogn_74_1 |
PubMedID: 20594636 |