Singh R

References (51)

Title : Crystal structure and solution scattering of Geobacillus stearothermophilus S9 peptidase reveal structural adaptations for carboxypeptidase activity - Chandravanshi_2024_FEBS.Lett__
Author(s) : Chandravanshi K , Singh R , Bhange GN , Kumar A , Yadav P , Makde RD
Ref : FEBS Letters , : , 2024
PubMedID: 38426217
Gene_locus related to this paper: geose-a0a3l7d5q2

Title : Optimized rat models better mimic patients with irinotecan-induced severe diarrhea - Zheng_2024_Toxicol.Mech.Methods__1
Author(s) : Zheng Z , Du T , Gao S , Yin T , Li L , Zhu L , Singh R , Sun R , Hu M
Ref : Toxicol Mech Methods , :1 , 2024
PubMedID: 38390772

Title : Pyrano[2,3-c]pyrazole fused spirooxindole-linked 1,2,3-triazoles as antioxidant agents: Exploring their utility in the development of antidiabetic drugs via inhibition of alpha-amylase and DPP4 activity - Chahal_2024_Bioorg.Chem_147_107363
Author(s) : Chahal S , Rani P , Shweta , Goel KK , Joshi G , Singh R , Kumar P , Singh D , Sindhu J
Ref : Bioorg Chem , 147 :107363 , 2024
PubMedID: 38657527

Title : Cyperus rotundus L.: Invasive weed plant with insecticidal potential against Aphis craccivora Koch and Planococcus lilacinus (Cockerell) - Singh_2024_Pestic.Biochem.Physiol_198_105720
Author(s) : Singh R , Gupta H , Anmol , Aggarwal G , Bhattacharyya K , Sharma U , Reddy SGE
Ref : Pestic Biochem Physiol , 198 :105720 , 2024
PubMedID: 38225075

Title : Effect of sulfonamide derivatives of phenylglycine on scopolamine-induced amnesia in rats - Ganeshpurkar_2023_Ibrain_9_13
Author(s) : Ganeshpurkar A , Singh R , Tripathi P , Alam Q , Krishnamurthy S , Kumar A , Singh SK
Ref : Ibrain , 9 :13 , 2023
PubMedID: 37786521

Title : N-Methylneolitsine as a new and potent acetylcholinesterase inhibitor of Cissampelos pareira Linn. aerial parts: bioassay-guided isolation and quantitative densitometric analysis - Haldar_2023_Nat.Prod.Res__1
Author(s) : Haldar S , Mohapatra S , Ganguly P , Paul N , Ash A , Biswas R , Singh R , Katiyar CK
Ref : Nat Prod Res , :1 , 2023
PubMedID: 37154600

Title : Cypermethrin toxicity in the environment: analytical Insight into detection methods and microbial degradation pathways - Kansal_2023_J.Appl.Microbiol__
Author(s) : Kansal I , Kapoor A , Solanki S , Singh R
Ref : J Appl Microbiol , : , 2023
PubMedID: 37197912

Title : Discovery of Multitarget-Directed Ligands from Piperidine Alkaloid Piperine as a Cap Group for the Management of Alzheimer's Disease - Bhanukiran_2023_ACS.Chem.Neurosci__
Author(s) : Bhanukiran K , Singh SK , Singh R , Kumar A , Hemalatha S
Ref : ACS Chem Neurosci , : , 2023
PubMedID: 37433759

Title : Ameliorating the Role of Aripiprazole in Memory Deficits Induced by Intracerebroventricular Streptozotocin-Induced Dementia of Alzheimer's Type - Gupta_2023_ACS.Omega_8_25295
Author(s) : Gupta T , Singh V , Hefnawy M , Alanazi MM , Alsuwayt B , Kabra A , Kumar A , Pasricha C , Singh R
Ref : ACS Omega , 8 :25295 , 2023
PubMedID: 37483219

Title : Identification of sulfonamide-based butyrylcholinesterase inhibitors using machine learning - Ganeshpurkar_2022_Future.Med.Chem__
Author(s) : Ganeshpurkar A , Singh R , Kumar D , Gutti G , Gore P , Sahu B , Kumar A , Singh SK
Ref : Future Med Chem , : , 2022
PubMedID: 35707942

Title : Identification of sulfonamide based butyrylcholinesterase inhibitors through scaffold hopping approach - Ganeshpurkar_2022_Int.J.Biol.Macromol__
Author(s) : Ganeshpurkar A , Singh R , Kumar D , Gore P , Shivhare S , Sardana D , Rayala S , Kumar A , Singh SK
Ref : Int J Biol Macromol , : , 2022
PubMedID: 35090939

Title : Identification of potential AChE inhibitors through combined machine-learning and structure-based design approaches - Ganeshpurkar_2022_Indian.J.Biochem.Biophys_59_619
Author(s) : Ganeshpurkar A , Singh R , Singh RB , Kumar D , Kumar A , Singh SK
Ref : Indian J Biochem Biophys , 59 :619 , 2022
PubMedID:

Title : Pharmacophore based virtual screening of cholinesterase inhibitors: search of new potential drug candidates as antialzheimer agents - Lakra_2022_In.Silico.Pharmacol_10_18
Author(s) : Lakra N , Matore BW , Banjare P , Singh R , Singh J , Roy PP
Ref : In Silico Pharmacol , 10 :18 , 2022
PubMedID: 36187087

Title : Phase 1 and pre-clinical profiling of ESM-HDAC391, a myeloid-targeted histone deacetylase inhibitor, shows enhanced pharmacology and monocytopaenia - Furze_2022_Br.J.Clin.Pharmacol__
Author(s) : Furze RC , Molnar J , Parr NJ , Ahmad F , Henry Y , Howe D , Singh R , Toal M , Bassil AK , Bernard SG , Davis RP , Gibson A , Maller NC , Sharp C , Tough DF , Prinjha RK , Lewis HD
Ref : British Journal of Clinical Pharmacology , : , 2022
PubMedID: 35655123

Title : Distribution of Fluoride in Plasma, Brain, and Bones and Associated Oxidative Damage After Induced Chronic Fluorosis in Wistar Rats - Sharma_2021_Biol.Trace.Elem.Res__
Author(s) : Sharma P , Verma PK , Sood S , Singh R , Gupta A , Rastogi A
Ref : Biol Trace Elem Res , : , 2021
PubMedID: 34128210

Title : Integration of System Biology Tools to Investigate Huperzine A as an Anti-Alzheimer Agent - Khanal_2021_Front.Pharmacol_12_785964
Author(s) : Khanal P , Zargari F , Far BF , Kumar D , R M , Mahdi YK , Jubair NK , Saraf SK , Bansal P , Singh R , Selvaraja M , Dey YN
Ref : Front Pharmacol , 12 :785964 , 2021
PubMedID: 34966281

Title : Amelioration of cognitive deficit in zebrafish by an undescribed anthraquinone from Juglans regia L.: An in-silico, in-vitro and in-vivo approach - Devidas_2021_Eur.J.Pharmacol__174234
Author(s) : Devidas SB , Rahmatkar SN , Singh R , Sendri N , Purohit R , Singh D , Bhandari P
Ref : European Journal of Pharmacology , :174234 , 2021
PubMedID: 34090895

Title : Improved machine learning scoring functions for identification of Electrophorus electricus's acetylcholinesterase inhibitors - Ganeshpurkar_2021_Mol.Divers__
Author(s) : Ganeshpurkar A , Singh R , Shivhare S , Divya , Kumar D , Gutti G , Kumar A , Singh SK
Ref : Mol Divers , : , 2021
PubMedID: 34328603

Title : Development of homology model, docking protocol and Machine-Learning based scoring functions for identification of Equus caballus's butyrylcholinesterase inhibitors - Ganeshpurkar_2021_J.Biomol.Struct.Dyn__1
Author(s) : Ganeshpurkar A , Singh R , Kumar D , Gutti G , Sardana D , Shivhare S , Singh RB , Kumar A , Singh SK
Ref : J Biomol Struct Dyn , :1 , 2021
PubMedID: 34696689

Title : 16-Substituted steroids alleviate LPS-induced neurodegenerative disorders in rats - Singh_2021_Eur.J.Pharmacol__173876
Author(s) : Singh R , Bansal R
Ref : European Journal of Pharmacology , :173876 , 2021
PubMedID: 33460614

Title : Microbial lipases and their industrial applications: a comprehensive review - Chandra_2020_Microb.Cell.Fact_19_169
Author(s) : Chandra P , Enespa , Singh R , Arora PK
Ref : Microb Cell Fact , 19 :169 , 2020
PubMedID: 32847584

Title : Non-insulin anti-diabetic agents in patients with type 2 diabetes and COVID-19: A Critical Appraisal of Literature - Singh_2020_Diabetes.Metab.Syndr_15_159
Author(s) : Singh AK , Singh R , Saboo B , Misra A
Ref : Diabetes Metab Syndr , 15 :159 , 2020
PubMedID: 33352455

Title : 16,17-N'-(alky\/arylsulfonyl)pyrazoline substituted neuroprotective heterosteroids: Synthesis, molecular docking and preclinical efficacy\/toxicity studies in rodents - Singh_2019_Steroids_148_114
Author(s) : Singh R , Bansal R
Ref : Steroids , 148 :114 , 2019
PubMedID: 31095966

Title : Protein-Protein Interactions and Aggregation Inhibitors in Alzheimer's Disease - Ganeshpurkar_2019_Curr.Top.Med.Chem_19_501
Author(s) : Ganeshpurkar A , Swetha R , Kumar D , Gangaram GP , Singh R , Gutti G , Jana S , Kumar A , Singh SK
Ref : Curr Top Med Chem , 19 :501 , 2019
PubMedID: 30836921

Title : Multifunctional hybrid sulfonamides as novel therapeutic agents for Alzheimer's disease - Swetha_2019_Future.Med.Chem_11_3161
Author(s) : Swetha R , Kumar D , Gupta SK , Ganeshpurkar A , Singh R , Gutti G , Jana S , Krishnamurthy S , Singh SK
Ref : Future Med Chem , 11 :3161 , 2019
PubMedID: 31838895

Title : Paraoxonase-1 is a better indicator than HDL of Atherosclerosis - A pilot study in North Indian population - Singh_2018_Diabetes.Metab.Syndr_12_275
Author(s) : Singh K , Singh R , Chandra S , Tyagi S
Ref : Diabetes Metab Syndr , 12 :275 , 2018
PubMedID: 29254890

Title : Studies on 16,17-Pyrazoline Substituted Heterosteroids as Anti-Alzheimer and Anti-Parkinsonian Agents Using LPS Induced Neuroinflammation Models of Mice and Rats - Singh_2018_ACS.Chem.Neurosci_9_272
Author(s) : Singh R , Thota S , Bansal R
Ref : ACS Chem Neurosci , 9 :272 , 2018
PubMedID: 29019394

Title : Epoxide hydrolase 1 (EPHX1) hydrolyzes epoxyeicosanoids and impairs cardiac recovery after ischemia - Edin_2018_J.Biol.Chem_293_3281
Author(s) : Edin ML , Hamedani BG , Gruzdev A , Graves JP , Lih FB , Arbes SJ, 3rd , Singh R , Orjuela Leon AC , Bradbury JA , DeGraff LM , Hoopes SL , Arand M , Zeldin DC
Ref : Journal of Biological Chemistry , 293 :3281 , 2018
PubMedID: 29298899
Gene_locus related to this paper: mouse-EPHX1 , mouse-hyes

Title : Rv0774c, an iron stress inducible, extracellular esterase is involved in immune-suppression associated with altered cytokine and TLR2 expression - Kumar_2017_Int.J.Med.Microbiol_307_126
Author(s) : Kumar A , Singh SM , Singh R , Kaur J
Ref : Int J Med Microbiol , 307 :126 , 2017
PubMedID: 28161108
Gene_locus related to this paper: myctu-RV0774C

Title : The Role of Food Antioxidants, Benefits of Functional Foods, and Influence of Feeding Habits on the Health of the Older Person: An Overview - Wilson_2017_Antioxidants.(Basel)_6_
Author(s) : Wilson DW , Nash P , Buttar HS , Griffiths K , Singh R , De Meester F , Horiuchi R , Takahashi T
Ref : Antioxidants (Basel) , 6 : , 2017
PubMedID: 29143759

Title : Thirty-degree shift in optimum temperature of a thermophilic lipase by a single-point mutation: effect of serine to threonine mutation on structural flexibility - Sharma_2017_Mol.Cell.Biochem_430_21
Author(s) : Sharma M , Kumar R , Singh R , Kaur J
Ref : Molecular & Cellular Biochemistry , 430 :21 , 2017
PubMedID: 28190170

Title : Point Mutation Ile137-Met Near Surface Conferred Psychrophilic Behaviour and Improved Catalytic Efficiency to Bacillus Lipase of 1.4 Subfamily - Goomber_2016_Appl.Biochem.Biotechnol_178_753
Author(s) : Goomber S , Kumar A , Singh R , Kaur J
Ref : Appl Biochem Biotechnol , 178 :753 , 2016
PubMedID: 26520838

Title : Point mutation Gln121-Arg increased temperature optima of Bacillus lipase (1.4 subfamily) by fifteen degrees - Goomber_2016_Int.J.Biol.Macromol_88_507
Author(s) : Goomber S , Kumar R , Singh R , Mishra N , Kaur J
Ref : Int J Biol Macromol , 88 :507 , 2016
PubMedID: 27083848

Title : In vitro degradation and cell attachment studies of a new electrospun polymeric tubular graft - Patel_2015_Prog.Biomater_4_67
Author(s) : Patel HN , Thai KN , Chowdhury S , Singh R , Vohra YK , Thomas V
Ref : Prog Biomater , 4 :67 , 2015
PubMedID: 26566465

Title : Effect of acyl chain length on selective biocatalytic deacylation on O-aryl glycosides and separation of anomers - Aggarwal_2014_Bioorg.Chem_53_83
Author(s) : Aggarwal N , Arya A , Mathur D , Singh S , Tyagi A , Kumar R , Rana N , Singh R , Prasad AK
Ref : Bioorg Chem , 53 :83 , 2014
PubMedID: 24632507

Title : Combinatorial reshaping of a lipase structure for thermostability: additive role of surface stabilizing single point mutations - Kumar_2014_Biochem.Biophys.Res.Commun_447_626
Author(s) : Kumar R , Singh R , Kaur J
Ref : Biochemical & Biophysical Research Communications , 447 :626 , 2014
PubMedID: 24751523

Title : Intrinsically Unstructured Carboxy Terminus of Bacillus Lipase is Essential for its Function - Khurana_2014_Protein.Pept.Lett_21_1265
Author(s) : Khurana J , Manisha , Singh R , Kaur J
Ref : Protein Pept Lett , 21 :1265 , 2014
PubMedID: 25001212

Title : Oil palm genome sequence reveals divergence of interfertile species in Old and New worlds - Singh_2013_Nature_500_335
Author(s) : Singh R , Ong-Abdullah M , Low ET , Manaf MA , Rosli R , Nookiah R , Ooi LC , Ooi SE , Chan KL , Halim MA , Azizi N , Nagappan J , Bacher B , Lakey N , Smith SW , He D , Hogan M , Budiman MA , Lee EK , Desalle R , Kudrna D , Goicoechea JL , Wing RA , Wilson RK , Fulton RS , Ordway JM , Martienssen RA , Sambanthamurthi R
Ref : Nature , 500 :335 , 2013
PubMedID: 23883927
Gene_locus related to this paper: elagv-a0a6i9rtu7 , elagv-a0a6i9set9

Title : Characterization and evolution of a metagenome-derived lipase towards enhanced enzyme activity and thermostability - Kumar_2013_Mol.Cell.Biochem_373_149
Author(s) : Kumar R , Sharma M , Singh R , Kaur J
Ref : Molecular & Cellular Biochemistry , 373 :149 , 2013
PubMedID: 23104399

Title : Characterization of a thermostable lipase showing loss of secondary structure at ambient temperature - Sharma_2012_Mol.Biol.Rep_39_2795
Author(s) : Sharma PK , Singh K , Singh R , Capalash N , Ali A , Mohammad O , Kaur J
Ref : Mol Biol Rep , 39 :2795 , 2012
PubMedID: 21678056

Title : Engineering of a metagenome derived lipase toward thermal tolerance: effect of asparagine to lysine mutation on the protein surface - Sharma_2012_Gene_491_264
Author(s) : Sharma PK , Kumar R , Mohammad O , Singh R , Kaur J
Ref : Gene , 491 :264 , 2012
PubMedID: 22001407

Title : Structure and function of the RedJ protein, a thioesterase from the prodiginine biosynthetic pathway in Streptomyces coelicolor - Whicher_2011_J.Biol.Chem_286_22558
Author(s) : Whicher JR , Florova G , Sydor PK , Singh R , Alhamadsheh M , Challis GL , Reynolds KA , Smith JL
Ref : Journal of Biological Chemistry , 286 :22558 , 2011
PubMedID: 21543318
Gene_locus related to this paper: strco-SC3F7.14

Title : Pharmacological management of delirium in hospitalized adults--a systematic evidence review - Campbell_2009_J.Gen.Intern.Med_24_848
Author(s) : Campbell N , Boustani MA , Ayub A , Fox GC , Munger SL , Ott C , Guzman O , Farber M , Ademuyiwa A , Singh R
Ref : J Gen Intern Med , 24 :848 , 2009
PubMedID: 19424763

Title : Curcumin counteracts the aluminium-induced ageing-related alterations in oxidative stress, Na+, K+ ATPase and protein kinase C in adult and old rat brain regions - Sharma_2009_Biogerontology_10_489
Author(s) : Sharma D , Sethi P , Hussain E , Singh R
Ref : Biogerontology , 10 :489 , 2009
PubMedID: 19020987

Title : Single-step purification of lipase from Burkholderia multivorans using polypropylene matrix - Gupta_2005_Appl.Microbiol.Biotechnol_67_648
Author(s) : Gupta N , Rathi P , Singh R , Goswami VK , Gupta R
Ref : Applied Microbiology & Biotechnology , 67 :648 , 2005
PubMedID: 15711795

Title : A secreted high-affinity inhibitor of human TNF from Tanapox virus - Brunetti_2003_Proc.Natl.Acad.Sci.U.S.A_100_4831
Author(s) : Brunetti CR , Paulose-Murphy M , Singh R , Qin J , Barrett JW , Tardivel A , Schneider P , Essani K , McFadden G
Ref : Proc Natl Acad Sci U S A , 100 :4831 , 2003
PubMedID: 12676996
Gene_locus related to this paper: ymtv-q6tuz7

Title : Magnitude of pesticidal contamination in winter vegetables from Hisar, Haryana - Kumari_2003_Environ.Monit.Assess_87_311
Author(s) : Kumari B , Kumar R , Madan VK , Singh R , Singh J , Kathpal TS
Ref : Environ Monit Assess , 87 :311 , 2003
PubMedID: 12952358

Title : Lewy body dementia: case report and discussion - Khotianov_2002_J.Am.Board.Fam.Pract_15_50
Author(s) : Khotianov N , Singh R , Singh S
Ref : J Am Board Fam Pract , 15 :50 , 2002
PubMedID: 11841138

Title : Centrophenoxine activates acetylcholinesterase activity in hippocampus of aged rats - Sharma_1995_Ind.J.Exp.Biol_33_365
Author(s) : Sharma D , Singh R
Ref : Indian Journal of Experimental Biology , 33 :365 , 1995
PubMedID: 7558197

Title : Pretreatment postural blood pressure drop as a possible predictor of response to the cholinesterase inhibitor velnacrine (HP 029) in Alzheimer's disease - Pomara_1991_Psychopharmacol.Bull_27_301
Author(s) : Pomara N , Deptula D , Singh R
Ref : Psychopharmacol Bull , 27 :301 , 1991
PubMedID: 1775603