Full name : Crooks Peter A
First name : Peter A. Crooks
Mail : Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences, Little Rock, Arizona
Zip Code :
City :
Country : USA
Email : pacrooks@uams.edu
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Comment
| Title : Novel hydroxybenzylamine-deoxyvasicinone hybrids as anticholinesterase therapeutics for Alzheimer's disease - Bowroju_2021_Bioorg.Med.Chem_45_116311 |
| Author(s) : Bowroju SK , Penthala NR , Lakkaniga NR , Balasubramaniam M , Ayyadevara S , Shmookler Reis RJ , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry , 45 :116311 , 2021 |
| Abstract : |
| PubMedSearch : Bowroju_2021_Bioorg.Med.Chem_45_116311 |
| PubMedID: 34304133 |
| Title : The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse - Nickell_2014_Adv.Pharmacol_69_71 |
| Author(s) : Nickell JR , Siripurapu KB , Vartak A , Crooks PA , Dwoskin LP |
| Ref : Advances in Pharmacology , 69 :71 , 2014 |
| Abstract : |
| PubMedSearch : Nickell_2014_Adv.Pharmacol_69_71 |
| PubMedID: 24484975 |
| Title : Nicotinic receptor antagonists as treatments for nicotine abuse - Crooks_2014_Adv.Pharmacol_69_513 |
| Author(s) : Crooks PA , Bardo MT , Dwoskin LP |
| Ref : Advances in Pharmacology , 69 :513 , 2014 |
| Abstract : |
| PubMedSearch : Crooks_2014_Adv.Pharmacol_69_513 |
| PubMedID: 24484986 |
| Title : Multiple Modes of alpha7 nAChR Noncompetitive Antagonism of Control Agonist-Evoked and Allosterically Enhanced Currents - Peng_2013_Mol.Pharmacol_84_459 |
| Author(s) : Peng C , Kimbrell MR , Tian C , Pack TF , Crooks PA , Fifer EK , Papke RL |
| Ref : Molecular Pharmacology , 84 :459 , 2013 |
| Abstract : |
| PubMedSearch : Peng_2013_Mol.Pharmacol_84_459 |
| PubMedID: 23839567 |
| Title : Discovery of non-peptide, small molecule antagonists of alpha9alpha10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain - Zheng_2011_Bioorg.Med.Chem.Lett_21_2476 |
| Author(s) : Zheng G , Zhang Z , Dowell C , Wala E , Dwoskin LP , Holtman JR , McIntosh JM , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :2476 , 2011 |
| Abstract : |
| PubMedSearch : Zheng_2011_Bioorg.Med.Chem.Lett_21_2476 |
| PubMedID: 21397497 |
| Title : The novel small molecule alpha9alpha10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic - Holtman_2011_Eur.J.Pharmacol_670_500 |
| Author(s) : Holtman JR , Dwoskin LP , Dowell C , Wala EP , Zhang Z , Crooks PA , McIntosh JM |
| Ref : European Journal of Pharmacology , 670 :500 , 2011 |
| Abstract : |
| PubMedSearch : Holtman_2011_Eur.J.Pharmacol_670_500 |
| PubMedID: 21944926 |
| Title : Phenyl ring-substituted lobelane analogs: inhibition of [(3)H]dopamine uptake at the vesicular monoamine transporter-2 - Nickell_2011_J.Pharmacol.Exp.Ther_336_724 |
| Author(s) : Nickell JR , Zheng G , Deaciuc AG , Crooks PA , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 336 :724 , 2011 |
| Abstract : |
| PubMedSearch : Nickell_2011_J.Pharmacol.Exp.Ther_336_724 |
| PubMedID: 20876747 |
| Title : meso-Transdiene analogs inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release - Horton_2011_J.Pharmacol.Exp.Ther_336_940 |
| Author(s) : Horton DB , Siripurapu KB , Norrholm SD , Culver JP , Hojahmat M , Beckmann JS , Harrod SB , Deaciuc AG , Bardo MT , Crooks PA , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 336 :940 , 2011 |
| Abstract : |
| PubMedSearch : Horton_2011_J.Pharmacol.Exp.Ther_336_940 |
| PubMedID: 21177475 |
| Title : Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release - Horton_2011_J.Pharmacol.Exp.Ther_339_286 |
| Author(s) : Horton DB , Siripurapu KB , Zheng G , Crooks PA , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 339 :286 , 2011 |
| Abstract : |
| PubMedSearch : Horton_2011_J.Pharmacol.Exp.Ther_339_286 |
| PubMedID: 21778282 |
| Title : Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse - Crooks_2011_Curr.Top.Med.Chem_11_1103 |
| Author(s) : Crooks PA , Zheng G , Vartak AP , Culver JP , Zheng F , Horton DB , Dwoskin LP |
| Ref : Curr Top Med Chem , 11 :1103 , 2011 |
| Abstract : |
| PubMedSearch : Crooks_2011_Curr.Top.Med.Chem_11_1103 |
| PubMedID: 21050177 |
| Title : bPiDI: a novel selective alpha6beta2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse - Wooters_2011_Br.J.Pharmacol_163_346 |
| Author(s) : Wooters TE , Smith AM , Pivavarchyk M , Siripurapu KB , McIntosh JM , Zhang Z , Crooks PA , Bardo MT , Dwoskin LP |
| Ref : British Journal of Pharmacology , 163 :346 , 2011 |
| Abstract : |
| PubMedSearch : Wooters_2011_Br.J.Pharmacol_163_346 |
| PubMedID: 21232049 |
| Title : Indolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release - Pivavarchyk_2011_Eur.J.Pharmacol_658_132 |
| Author(s) : Pivavarchyk M , Smith AM , Zhang Z , Zhou D , Wang X , Toyooka N , Tsuneki H , Sasaoka T , McIntosh JM , Crooks PA , Dwoskin LP |
| Ref : European Journal of Pharmacology , 658 :132 , 2011 |
| Abstract : |
| PubMedSearch : Pivavarchyk_2011_Eur.J.Pharmacol_658_132 |
| PubMedID: 21371454 |
| Title : Novel bis-, tris-, and tetrakis-tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release - Zhang_2011_Bioorg.Med.Chem.Lett_21_88 |
| Author(s) : Zhang Z , Zheng G , Pivavarchyk M , Deaciuc AG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :88 , 2011 |
| Abstract : |
| PubMedSearch : Zhang_2011_Bioorg.Med.Chem.Lett_21_88 |
| PubMedID: 21147530 |
| Title : The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats - Beckmann_2010_J.Pharmacol.Exp.Ther_335_841 |
| Author(s) : Beckmann JS , Siripurapu KB , Nickell JR , Horton DB , Denehy ED , Vartak A , Crooks PA , Dwoskin LP , Bardo MT |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 335 :841 , 2010 |
| Abstract : |
| PubMedSearch : Beckmann_2010_J.Pharmacol.Exp.Ther_335_841 |
| PubMedID: 20805303 |
| Title : Predictive screening model for potential vector-mediated transport of cationic substrates at the blood-brain barrier choline transporter - Geldenhuys_2010_Bioorg.Med.Chem.Lett_20_870 |
| Author(s) : Geldenhuys WJ , Manda VK , Mittapalli RK , Van der Schyf CJ , Crooks PA , Dwoskin LP , Allen DD , Lockman PR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :870 , 2010 |
| Abstract : |
| PubMedSearch : Geldenhuys_2010_Bioorg.Med.Chem.Lett_20_870 |
| PubMedID: 20053562 |
| Title : Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release - Smith_2010_Biochem.Pharmacol_80_402 |
| Author(s) : Smith AM , Pivavarchyk M , Wooters TE , Zhang Z , Zheng G , McIntosh JM , Crooks PA , Bardo MT , Dwoskin LP |
| Ref : Biochemical Pharmacology , 80 :402 , 2010 |
| Abstract : |
| PubMedSearch : Smith_2010_Biochem.Pharmacol_80_402 |
| PubMedID: 20346923 |
| Title : Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters - Hojahmat_2010_Bioorg.Med.Chem_18_640 |
| Author(s) : Hojahmat M , Horton DB , Norrholm SD , Miller DK , Grinevich VP , Deaciuc AG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry , 18 :640 , 2010 |
| Abstract : |
| PubMedSearch : Hojahmat_2010_Bioorg.Med.Chem_18_640 |
| PubMedID: 20036131 |
| Title : Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2 - Nickell_2010_J.Pharmacol.Exp.Ther_332_612 |
| Author(s) : Nickell JR , Krishnamurthy S , Norrholm S , Deaciuc G , Siripurapu KB , Zheng G , Crooks PA , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 332 :612 , 2010 |
| Abstract : |
| PubMedSearch : Nickell_2010_J.Pharmacol.Exp.Ther_332_612 |
| PubMedID: 19855096 |
| Title : Novel bis-2,2,6,6-tetramethylpiperidine (bis-TMP) and bis-mecamylamine antagonists at neuronal nicotinic receptors mediating nicotine-evoked dopamine release - Zhang_2010_Bioorg.Med.Chem.Lett_20_1420 |
| Author(s) : Zhang Z , Pivavarchyk M , Subramanian KL , Deaciuc AG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1420 , 2010 |
| Abstract : |
| PubMedSearch : Zhang_2010_Bioorg.Med.Chem.Lett_20_1420 |
| PubMedID: 20079634 |
| Title : Selective inhibition of acetylcholine-evoked responses of alpha7 neuronal nicotinic acetylcholine receptors by novel tris- and tetrakis-azaaromatic quaternary ammonium antagonists - Lopez-Hernandez_2009_Mol.Pharmacol_76_652 |
| Author(s) : Lopez-Hernandez GY , Thinschmidt JS , Zheng G , Zhang Z , Crooks PA , Dwoskin LP , Papke RL |
| Ref : Molecular Pharmacology , 76 :652 , 2009 |
| Abstract : |
| PubMedSearch : Lopez-Hernandez_2009_Mol.Pharmacol_76_652 |
| PubMedID: 19556356 |
| Title : Nicotinic receptor-based therapeutics and candidates for smoking cessation - Dwoskin_2009_Biochem.Pharmacol_78(7)_732 |
| Author(s) : Dwoskin LP , Smith AM , Wooters TE , Zhang Z , Crooks PA , Bardo MT |
| Ref : Biochemical Pharmacology , 78 :732 , 2009 |
| Abstract : |
| PubMedSearch : Dwoskin_2009_Biochem.Pharmacol_78(7)_732 |
| PubMedID: 19523455 |
| Title : Mecamylamine, dihydro-beta-erythroidine, and dextromethorphan block conditioned responding evoked by the conditional stimulus effects of nicotine - Struthers_2009_Pharmacol.Biochem.Behav_94_319 |
| Author(s) : Struthers AM , Wilkinson JL , Dwoskin LP , Crooks PA , Bevins RA |
| Ref : Pharmacol Biochem Behav , 94 :319 , 2009 |
| Abstract : |
| PubMedSearch : Struthers_2009_Pharmacol.Biochem.Behav_94_319 |
| PubMedID: 19778551 |
| Title : The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices - Smith_2009_Biochem.Pharmacol_78(7)_889 |
| Author(s) : Smith AM , Dhawan GK , Zhang Z , Siripurapu KB , Crooks PA , Dwoskin LP |
| Ref : Biochemical Pharmacology , 78 :889 , 2009 |
| Abstract : |
| PubMedSearch : Smith_2009_Biochem.Pharmacol_78(7)_889 |
| PubMedID: 19631612 |
| Title : Poster: GZ556A and ZZ204G are novel small molecule antagonists of alpha9alpha10 nAChRs and are analgesic in rats - |
| Author(s) : McIntosh JM , Dwoskin LP , Crooks PA , Holtman Jr JR |
| Ref : Biochemical Pharmacology , 78 :921 , 2009 |
| PubMedID: |
| Title : Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence - |
| Author(s) : Dwoskin LP , Pivavarchyk M , Joyce BM , Neugebauer NM , Zheng G , Zhang Z , Bardo MT , Crooks PA |
| Ref : Nebr Symp Motiv , 55 :31 , 2009 |
| PubMedID: 19013938 |
| Title : First-Principles Determination of Molecular Conformations of Indolizidine (-)-235B' in Solution - Zheng_2009_Theor.Chem.Acc_124_269 |
| Author(s) : Zheng F , Dwoskin LP , Crooks PA , Zhan CG |
| Ref : Theor Chem Acc , 124 :269 , 2009 |
| Abstract : |
| PubMedSearch : Zheng_2009_Theor.Chem.Acc_124_269 |
| PubMedID: 20161506 |
| Title : QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum - Zheng_2009_Bioorg.Med.Chem_17_4477 |
| Author(s) : Zheng F , McConnell MJ , Zhan CG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry , 17 :4477 , 2009 |
| Abstract : |
| PubMedSearch : Zheng_2009_Bioorg.Med.Chem_17_4477 |
| PubMedID: 19477134 |
| Title : Computational neural network analysis of the affinity of N-n-alkylnicotinium salts for the alpha4beta2* nicotinic acetylcholine receptor - Zheng_2009_J.Enzyme.Inhib.Med.Chem_24_157 |
| Author(s) : Zheng F , Zheng G , Deaciuc AG , Zhan CG , Dwoskin LP , Crooks PA |
| Ref : J Enzyme Inhib Med Chem , 24 :157 , 2009 |
| Abstract : |
| PubMedSearch : Zheng_2009_J.Enzyme.Inhib.Med.Chem_24_157 |
| PubMedID: 18629679 |
| Title : Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras - Papke_2008_Neuropharmacol_54_1189 |
| Author(s) : Papke RL , Dwoskin LP , Crooks PA , Zheng G , Zhang Z , McIntosh JM , Stokes C |
| Ref : Neuropharmacology , 54 :1189 , 2008 |
| Abstract : |
| PubMedSearch : Papke_2008_Neuropharmacol_54_1189 |
| PubMedID: 18448138 |
| Title : Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release - Zhang_2008_Bioorg.Med.Chem.Lett_18_5753 |
| Author(s) : Zhang Z , Zheng G , Pivavarchyk M , Deaciuc AG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5753 , 2008 |
| Abstract : |
| PubMedSearch : Zhang_2008_Bioorg.Med.Chem.Lett_18_5753 |
| PubMedID: 18851914 |
| Title : The novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens - Rahman_2008_Eur.J.Pharmacol_601_103 |
| Author(s) : Rahman S , Neugebauer NM , Zhang Z , Crooks PA , Dwoskin LP , Bardo MT |
| Ref : European Journal of Pharmacology , 601 :103 , 2008 |
| Abstract : |
| PubMedSearch : Rahman_2008_Eur.J.Pharmacol_601_103 |
| PubMedID: 19000671 |
| Title : N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity - Dwoskin_2008_J.Pharmacol.Exp.Ther_326_563 |
| Author(s) : Dwoskin LP , Wooters TE , Sumithran SP , Siripurapu KB , Joyce BM , Lockman PR , Manda VK , Ayers JT , Zhang Z , Deaciuc AG , McIntosh JM , Crooks PA , Bardo MT |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 326 :563 , 2008 |
| Abstract : |
| PubMedSearch : Dwoskin_2008_J.Pharmacol.Exp.Ther_326_563 |
| PubMedID: 18460644 |
| Title : Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier - Lockman_2008_J.Pharmacol.Exp.Ther_324_244 |
| Author(s) : Lockman PR , Manda VK , Geldenhuys WJ , Mittapalli RK , Thomas F , Albayati ZF , Crooks PA , Dwoskin LP , Allen DD |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 324 :244 , 2008 |
| Abstract : |
| PubMedSearch : Lockman_2008_J.Pharmacol.Exp.Ther_324_244 |
| PubMedID: 17921191 |
| Title : Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo - Rahman_2008_Br.J.Pharmacol_153_792 |
| Author(s) : Rahman S , Zhang Z , Papke RL , Crooks PA , Dwoskin LP , Bardo MT |
| Ref : British Journal of Pharmacology , 153 :792 , 2008 |
| Abstract : |
| PubMedSearch : Rahman_2008_Br.J.Pharmacol_153_792 |
| PubMedID: 18059317 |
| Title : Pharmacokinetics of the novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat - Albayati_2008_Drug.Metab.Dispos_36_2024 |
| Author(s) : Albayati ZA , Dwoskin LP , Crooks PA |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 36 :2024 , 2008 |
| Abstract : |
| PubMedSearch : Albayati_2008_Drug.Metab.Dispos_36_2024 |
| PubMedID: 18617603 |
| Title : Tris-azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release - Zheng_2007_Bioorg.Med.Chem.Lett_17_6701 |
| Author(s) : Zheng G , Sumithran SP , Deaciuc AG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :6701 , 2007 |
| Abstract : |
| PubMedSearch : Zheng_2007_Bioorg.Med.Chem.Lett_17_6701 |
| PubMedID: 17977723 |
| Title : Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation - Zheng_2007_Bioorg.Med.Chem.Lett_17_6734 |
| Author(s) : Zheng G , Zhang Z , Pivavarchyk M , Deaciuc AG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 17 :6734 , 2007 |
| Abstract : |
| PubMedSearch : Zheng_2007_Bioorg.Med.Chem.Lett_17_6734 |
| PubMedID: 18029180 |
| Title : Nornicotine inhibition of dopamine transporter function in striatum via nicotinic receptor activation - Middleton_2007_Synapse_61_157 |
| Author(s) : Middleton LS , Crooks PA , Wedlund PJ , Cass WA , Dwoskin LP |
| Ref : Synapse , 61 :157 , 2007 |
| Abstract : |
| PubMedSearch : Middleton_2007_Synapse_61_157 |
| PubMedID: 17146768 |
| Title : Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD) - Dwoskin_2007_Biochem.Pharmacol_74(8)_1271 |
| Author(s) : Dwoskin LP , Joyce BM , Zheng G , Neugebauer NM , Manda VK , Lockman P , Papke RL , Bardo MT , Crooks PA |
| Ref : Biochemical Pharmacology , 74 :1271 , 2007 |
| Abstract : |
| PubMedSearch : Dwoskin_2007_Biochem.Pharmacol_74(8)_1271 |
| PubMedID: 17727820 |
| Title : The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery - Papke_2007_J.Neurochem_101_160 |
| Author(s) : Papke RL , Dwoskin LP , Crooks PA |
| Ref : Journal of Neurochemistry , 101 :160 , 2007 |
| Abstract : |
| PubMedSearch : Papke_2007_J.Neurochem_101_160 |
| PubMedID: 17241116 |
| Title : The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens - Rahman_2007_Neuropharmacol_52_755 |
| Author(s) : Rahman S , Neugebauer NM , Zhang Z , Crooks PA , Dwoskin LP , Bardo MT |
| Ref : Neuropharmacology , 52 :755 , 2007 |
| Abstract : |
| PubMedSearch : Rahman_2007_Neuropharmacol_52_755 |
| PubMedID: 17097117 |
| Title : Computational neural network analysis of the affinity of lobeline and tetrabenazine analogs for the vesicular monoamine transporter-2 - Zheng_2007_Bioorg.Med.Chem_15_2975 |
| Author(s) : Zheng F , Zheng G , Deaciuc AG , Zhan CG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry , 15 :2975 , 2007 |
| Abstract : |
| PubMedSearch : Zheng_2007_Bioorg.Med.Chem_15_2975 |
| PubMedID: 17331733 |
| Title : Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats - Neugebauer_2006_Psychopharmacology.(Berl)_184_426 |
| Author(s) : Neugebauer NM , Zhang Z , Crooks PA , Dwoskin LP , Bardo MT |
| Ref : Psychopharmacology (Berl) , 184 :426 , 2006 |
| Abstract : |
| PubMedSearch : Neugebauer_2006_Psychopharmacology.(Berl)_184_426 |
| PubMedID: 16220336 |
| Title : N, N -disubstituted piperazines and homopiperazines: synthesis and affinities at alpha4beta2* and alpha7* neuronal nicotinic acetylcholine receptors - Chen_2006_J.Enzyme.Inhib.Med.Chem_21_667 |
| Author(s) : Chen J , Deaciuc AG , Dwoskin LP , Crooks PA , Bai D |
| Ref : J Enzyme Inhib Med Chem , 21 :667 , 2006 |
| Abstract : |
| PubMedSearch : Chen_2006_J.Enzyme.Inhib.Med.Chem_21_667 |
| PubMedID: 17252939 |
| Title : Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions - Huang_2006_J.Med.Chem_49_7661 |
| Author(s) : Huang X , Zheng F , Chen X , Crooks PA , Dwoskin LP , Zhan CG |
| Ref : Journal of Medicinal Chemistry , 49 :7661 , 2006 |
| Abstract : |
| PubMedSearch : Huang_2006_J.Med.Chem_49_7661 |
| PubMedID: 17181149 |
| Title : QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release - Zheng_2006_Bioorg.Med.Chem_14_3017 |
| Author(s) : Zheng F , Bayram E , Sumithran SP , Ayers JT , Zhan CG , Schmitt JD , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry , 14 :3017 , 2006 |
| Abstract : |
| PubMedSearch : Zheng_2006_Bioorg.Med.Chem_14_3017 |
| PubMedID: 16431111 |
| Title : Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters - Zheng_2006_Bioorg.Med.Chem.Lett_16_5018 |
| Author(s) : Zheng G , Horton DB , Deaciuc AG , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 16 :5018 , 2006 |
| Abstract : |
| PubMedSearch : Zheng_2006_Bioorg.Med.Chem.Lett_16_5018 |
| PubMedID: 16905316 |
| Title : Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the alpha4beta2 nicotinic acetylcholine receptor subtype using nonlinear techniques - Ayers_2005_AAPS.J_7_E678 |
| Author(s) : Ayers JT , Clauset A , Schmitt JD , Dwoskin LP , Crooks PA |
| Ref : AAPS J , 7 :E678 , 2005 |
| Abstract : |
| PubMedSearch : Ayers_2005_AAPS.J_7_E678 |
| PubMedID: 16353944 |
| Title : A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine - Ayers_2005_AAPS.J_7_E752 |
| Author(s) : Ayers JT , Xu R , Dwoskin LP , Crooks PA |
| Ref : AAPS J , 7 :E752 , 2005 |
| Abstract : |
| PubMedSearch : Ayers_2005_AAPS.J_7_E752 |
| PubMedID: 16353951 |
| Title : Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity - Sumithran_2005_AAPS.J_7_E201 |
| Author(s) : Sumithran SP , Crooks PA , Xu R , Zhu J , Deaciuc AG , Wilkins LH , Dwoskin LP |
| Ref : AAPS J , 7 :E201 , 2005 |
| Abstract : |
| PubMedSearch : Sumithran_2005_AAPS.J_7_E201 |
| PubMedID: 16146341 |
| Title : Modeling multiple species of nicotine and deschloroepibatidine interacting with alpha4beta2 nicotinic acetylcholine receptor: from microscopic binding to phenomenological binding affinity - Huang_2005_J.Am.Chem.Soc_127_14401 |
| Author(s) : Huang X , Zheng F , Crooks PA , Dwoskin LP , Zhan CG |
| Ref : Journal of the American Chemical Society , 127 :14401 , 2005 |
| Abstract : |
| PubMedSearch : Huang_2005_J.Am.Chem.Soc_127_14401 |
| PubMedID: 16218635 |
| Title : The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion - Papke_2005_Bioorg.Med.Chem.Lett_15_3874 |
| Author(s) : Papke RL , Zheng G , Horenstein NA , Dwoskin LP , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 15 :3874 , 2005 |
| Abstract : |
| PubMedSearch : Papke_2005_Bioorg.Med.Chem.Lett_15_3874 |
| PubMedID: 16005216 |
| Title : Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: affinity for neuronal nicotinic acetylcholine receptors - Wei_2005_Life.Sci_78_495 |
| Author(s) : Wei X , Sumithran SP , Deaciuc AG , Burton HR , Bush LP , Dwoskin LP , Crooks PA |
| Ref : Life Sciences , 78 :495 , 2005 |
| Abstract : |
| PubMedSearch : Wei_2005_Life.Sci_78_495 |
| PubMedID: 16197964 |
| Title : N-n-alkylnicotinium analogs, a novel class of antagonists at alpha 4 beta 2* nicotinic acetylcholine receptors: inhibition of S(-)-nicotine-evoked 86Rb+ efflux from rat thalamic synaptosomes - Wilkins_2005_AAPS.J_7_E922 |
| Author(s) : Wilkins LH, Jr. , Miller DK , Ayers JT , Crooks PA , Dwoskin LP |
| Ref : AAPS J , 7 :E922 , 2005 |
| Abstract : |
| PubMedSearch : Wilkins_2005_AAPS.J_7_E922 |
| PubMedID: 16594645 |
| Title : Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands - Zheng_2005_Bioorg.Med.Chem.Lett_15_4463 |
| Author(s) : Zheng G , Dwoskin LP , Deaciuc AG , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 15 :4463 , 2005 |
| Abstract : |
| PubMedSearch : Zheng_2005_Bioorg.Med.Chem.Lett_15_4463 |
| PubMedID: 16112864 |
| Title : Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter - Zheng_2005_J.Med.Chem_48_5551 |
| Author(s) : Zheng G , Dwoskin LP , Deaciuc AG , Norrholm SD , Crooks PA |
| Ref : Journal of Medicinal Chemistry , 48 :5551 , 2005 |
| Abstract : |
| PubMedSearch : Zheng_2005_J.Med.Chem_48_5551 |
| PubMedID: 16107155 |
| Title : Lobelane analogues as novel ligands for the vesicular monoamine transporter-2 - Zheng_2005_Bioorg.Med.Chem_13_3899 |
| Author(s) : Zheng G , Dwoskin LP , Deaciuc AG , Zhu J , Jones MD , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry , 13 :3899 , 2005 |
| Abstract : |
| PubMedSearch : Zheng_2005_Bioorg.Med.Chem_13_3899 |
| PubMedID: 15911306 |
| Title : Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters - Miller_2004_J.Pharmacol.Exp.Ther_310_1035 |
| Author(s) : Miller DK , Crooks PA , Zheng G , Grinevich VP , Norrholm SD , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 310 :1035 , 2004 |
| Abstract : |
| PubMedSearch : Miller_2004_J.Pharmacol.Exp.Ther_310_1035 |
| PubMedID: 15121762 |
| Title : Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release - Crooks_2004_Bioorg.Med.Chem.Lett_14_1869 |
| Author(s) : Crooks PA , Ayers JT , Xu R , Sumithran SP , Grinevich VP , Wilkins LH , Deaciuc AG , Allen DD , Dwoskin LP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1869 , 2004 |
| Abstract : |
| PubMedSearch : Crooks_2004_Bioorg.Med.Chem.Lett_14_1869 |
| PubMedID: 15050618 |
| Title : Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents - Dwoskin_2004_Bioorg.Med.Chem.Lett_14_1863 |
| Author(s) : Dwoskin LP , Sumithran SP , Zhu J , Deaciuc AG , Ayers JT , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1863 , 2004 |
| Abstract : |
| PubMedSearch : Dwoskin_2004_Bioorg.Med.Chem.Lett_14_1863 |
| PubMedID: 15050617 |
| Title : N,N-disubstituted piperazines: synthesis and affinities at alpha4beta2(*) and alpha7(*) neuronal nicotinic acetylcholine receptors - Chen_2003_Bioorg.Med.Chem.Lett_13_97 |
| Author(s) : Chen J , Norrholm S , Dwoskin LP , Crooks PA , Bai D |
| Ref : Bioorganic & Medicinal Chemistry Lett , 13 :97 , 2003 |
| Abstract : |
| PubMedSearch : Chen_2003_Bioorg.Med.Chem.Lett_13_97 |
| PubMedID: 12467625 |
| Title : N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors - Wilkins_2003_J.Pharmacol.Exp.Ther_304_400 |
| Author(s) : Wilkins LH, Jr. , Grinevich VP , Ayers JT , Crooks PA , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 304 :400 , 2003 |
| Abstract : |
| PubMedSearch : Wilkins_2003_J.Pharmacol.Exp.Ther_304_400 |
| PubMedID: 12490617 |
| Title : N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices - Grinevich_2003_J.Pharmacol.Exp.Ther_306_1011 |
| Author(s) : Grinevich VP , Crooks PA , Sumithran SP , Haubner AJ , Ayers JT , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 306 :1011 , 2003 |
| Abstract : |
| PubMedSearch : Grinevich_2003_J.Pharmacol.Exp.Ther_306_1011 |
| PubMedID: 12766255 |
| Title : N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonist: inhibition of S(-)-nicotine-evoked [(3)H]dopamine overflow from superfused rat striatal slices - Wilkins_2002_J.Pharmacol.Exp.Ther_301_1088 |
| Author(s) : Wilkins LH, Jr. , Haubner A , Ayers JT , Crooks PA , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 301 :1088 , 2002 |
| Abstract : |
| PubMedSearch : Wilkins_2002_J.Pharmacol.Exp.Ther_301_1088 |
| PubMedID: 12023541 |
| Title : A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse - Dwoskin_2002_Biochem.Pharmacol_63_89 |
| Author(s) : Dwoskin LP , Crooks PA |
| Ref : Biochemical Pharmacology , 63 :89 , 2002 |
| Abstract : |
| PubMedSearch : Dwoskin_2002_Biochem.Pharmacol_63_89 |
| PubMedID: 11841781 |
| Title : bis-Azaaromatic quaternary ammonium analogues: ligands for alpha4beta2* and alpha7* subtypes of neuronal nicotinic receptors - Ayers_2002_Bioorg.Med.Chem.Lett_12_3067 |
| Author(s) : Ayers JT , Dwoskin LP , Deaciuc AG , Grinevich VP , Zhu J , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 12 :3067 , 2002 |
| Abstract : |
| PubMedSearch : Ayers_2002_Bioorg.Med.Chem.Lett_12_3067 |
| PubMedID: 12372503 |
| Title : Once weekly administration of nicotine produces long-lasting locomotor sensitization in rats via a nicotinic receptor-mediated mechanism - Miller_2001_Psychopharmacology.(Berl)_156_469 |
| Author(s) : Miller DK , Wilkins LH , Bardo MT , Crooks PA , Dwoskin LP |
| Ref : Psychopharmacology (Berl) , 156 :469 , 2001 |
| Abstract : |
| PubMedSearch : Miller_2001_Psychopharmacology.(Berl)_156_469 |
| PubMedID: 11498725 |
| Title : Contributory role for nornicotine in nicotine neuropharmacology: nornicotine-evoked [3H]dopamine overflow from rat nucleus accumbens slices - Green_2001_Biochem.Pharmacol_62_1597 |
| Author(s) : Green TA , Crooks PA , Bardo MT , Dwoskin LP |
| Ref : Biochemical Pharmacology , 62 :1597 , 2001 |
| Abstract : |
| PubMedSearch : Green_2001_Biochem.Pharmacol_62_1597 |
| PubMedID: 11755112 |
| Title : Lobeline attenuates d-methamphetamine self-administration in rats - Harrod_2001_J.Pharmacol.Exp.Ther_298_172 |
| Author(s) : Harrod SB , Dwoskin LP , Crooks PA , Klebaur JE , Bardo MT |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 298 :172 , 2001 |
| Abstract : |
| PubMedSearch : Harrod_2001_J.Pharmacol.Exp.Ther_298_172 |
| PubMedID: 11408539 |
| Title : Pharmacological differences between immunoisolated native brain and heterologously expressed rat alpha4beta2 nicotinic receptors - Truong_2001_Brain.Res.Mol.Brain.Res_96_68 |
| Author(s) : Truong A , Xing X , Forsayeth JR , Dwoskin LP , Crooks PA , Cohen BN |
| Ref : Brain Research Mol Brain Res , 96 :68 , 2001 |
| Abstract : |
| PubMedSearch : Truong_2001_Brain.Res.Mol.Brain.Res_96_68 |
| PubMedID: 11731010 |
| Title : Neuronal nicotinic acetylcholine receptor binding affinities of boron-containing nicotine analogues - Xu_2001_Bioorg.Med.Chem.Lett_11_1245 |
| Author(s) : Xu R , Dwoskin LP , Grinevich VP , Deaciuc G , Crooks PA |
| Ref : Bioorganic & Medicinal Chemistry Lett , 11 :1245 , 2001 |
| Abstract : |
| PubMedSearch : Xu_2001_Bioorg.Med.Chem.Lett_11_1245 |
| PubMedID: 11354387 |
| Title : Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery - Dwoskin_2001_J.Pharmacol.Exp.Ther_298_395 |
| Author(s) : Dwoskin LP , Crooks PA |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 298 :395 , 2001 |
| Abstract : |
| PubMedSearch : Dwoskin_2001_J.Pharmacol.Exp.Ther_298_395 |
| PubMedID: 11454899 |
| Title : Nornicotine, a nicotine metabolite and tobacco alkaloid: desensitization of nicotinic receptor-stimulated dopamine release from rat striatum - Dwoskin_2001_Eur.J.Pharmacol_428_69 |
| Author(s) : Dwoskin LP , Teng LH , Crooks PA |
| Ref : European Journal of Pharmacology , 428 :69 , 2001 |
| Abstract : |
| PubMedSearch : Dwoskin_2001_Eur.J.Pharmacol_428_69 |
| PubMedID: 11779039 |
| Title : Lobeline inhibits nicotine-evoked [(3)H]dopamine overflow from rat striatal slices and nicotine-evoked (86)Rb(+) efflux from thalamic synaptosomes - Miller_2000_Neuropharmacol_39_2654 |
| Author(s) : Miller DK , Crooks PA , Dwoskin LP |
| Ref : Neuropharmacology , 39 :2654 , 2000 |
| Abstract : |
| PubMedSearch : Miller_2000_Neuropharmacol_39_2654 |
| PubMedID: 11044735 |
| Title : Nornicotine pretreatment decreases intravenous nicotine self-administration in rats - Green_2000_Psychopharmacology.(Berl)_152_289 |
| Author(s) : Green TA , Phillips SB , Crooks PA , Dwoskin LP , Bardo MT |
| Ref : Psychopharmacology (Berl) , 152 :289 , 2000 |
| Abstract : |
| PubMedSearch : Green_2000_Psychopharmacology.(Berl)_152_289 |
| PubMedID: 11105939 |
| Title : Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2'-(14)C]nicotine - Ghosheh_1999_Drug.Metab.Dispos_27_1448 |
| Author(s) : Ghosheh O , Dwoskin LP , Li WK , Crooks PA |
| Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 27 :1448 , 1999 |
| Abstract : |
| PubMedSearch : Ghosheh_1999_Drug.Metab.Dispos_27_1448 |
| PubMedID: 10570026 |
| Title : Pharmacological similarities between native brain and heterologously expressed alpha4beta2 nicotinic receptors - Shafaee_1999_Br.J.Pharmacol_128_1291 |
| Author(s) : Shafaee N , Houng M , Truong A , Viseshakul N , Figl A , Sandhu S , Forsayeth JR , Dwoskin LP , Crooks PA , Cohen BN |
| Ref : British Journal of Pharmacology , 128 :1291 , 1999 |
| Abstract : |
| PubMedSearch : Shafaee_1999_Br.J.Pharmacol_128_1291 |
| PubMedID: 10578144 |
| Title : (S)-(-)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H]dopamine release from rat striatal slices in a calcium-dependent manner - Dwoskin_1999_J.Pharmacol.Exp.Ther_288_905 |
| Author(s) : Dwoskin LP , Teng L , Buxton ST , Crooks PA |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 288 :905 , 1999 |
| Abstract : |
| PubMedSearch : Dwoskin_1999_J.Pharmacol.Exp.Ther_288_905 |
| PubMedID: 10027825 |
| Title : Acute and chronic effects of nornicotine on locomotor activity in rats: altered response to nicotine - Dwoskin_1999_Psychopharmacology.(Berl)_145_442 |
| Author(s) : Dwoskin LP , Crooks PA , Teng L , Green TA , Bardo MT |
| Ref : Psychopharmacology (Berl) , 145 :442 , 1999 |
| Abstract : |
| PubMedSearch : Dwoskin_1999_Psychopharmacology.(Berl)_145_442 |
| PubMedID: 10460322 |
| Title : Development of a novel class of subtype-selective nicotinic receptor antagonist: pyridine-N-substituted nicotine analogs - |
| Author(s) : Dwoskin LP , Wilkins LH , Pauly JR , Crooks PA |
| Ref : Annals of the New York Academy of Sciences , 868 :617 , 1999 |
| PubMedID: 10414342 |
| Title : Lobeline displaces [3H]dihydrotetrabenazine binding and releases [3H]dopamine from rat striatal synaptic vesicles: comparison with d-amphetamine - Teng_1998_J.Neurochem_71_258 |
| Author(s) : Teng L , Crooks PA , Dwoskin LP |
| Ref : Journal of Neurochemistry , 71 :258 , 1998 |
| Abstract : |
| PubMedSearch : Teng_1998_J.Neurochem_71_258 |
| PubMedID: 9648873 |
| Title : (-)-Nornicotine partially substitutes for (+)-amphetamine in a drug discrimination paradigm in rats - Bardo_1997_Pharmacol.Biochem.Behav_58_1083 |
| Author(s) : Bardo MT , Bevins RA , Klebaur JE , Crooks PA , Dwoskin LP |
| Ref : Pharmacol Biochem Behav , 58 :1083 , 1997 |
| Abstract : |
| PubMedSearch : Bardo_1997_Pharmacol.Biochem.Behav_58_1083 |
| PubMedID: 9408217 |
| Title : Nicotinic-receptor mediation of S(-)nornicotine-evoked -3H-overflow from rat striatal slices preloaded with -3H-dopamine - Teng_1997_J.Pharmacol.Exp.Ther_283_778 |
| Author(s) : Teng L , Crooks PA , Buxton ST , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 283 :778 , 1997 |
| Abstract : |
| PubMedSearch : Teng_1997_J.Pharmacol.Exp.Ther_283_778 |
| PubMedID: 9353398 |
| Title : Lobeline and nicotine evoke [3H]overflow from rat striatal slices preloaded with [3H]dopamine: differential inhibition of synaptosomal and vesicular [3H]dopamine uptake - Teng_1997_J.Pharmacol.Exp.Ther_280_1432 |
| Author(s) : Teng L , Crooks PA , Sonsalla PK , Dwoskin LP |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 280 :1432 , 1997 |
| Abstract : |
| PubMedSearch : Teng_1997_J.Pharmacol.Exp.Ther_280_1432 |
| PubMedID: 9067333 |
| Title : Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking - Crooks_1997_Biochem.Pharmacol_54_743 |
| Author(s) : Crooks PA , Dwoskin LP |
| Ref : Biochemical Pharmacology , 54 :743 , 1997 |
| Abstract : |
| PubMedSearch : Crooks_1997_Biochem.Pharmacol_54_743 |
| PubMedID: 9353128 |