Dwoskin LP

General

Full name : Dwoskin Linda P

First name : Linda P

Mail : Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, Kentucky

Zip Code :

City :

Country : USA

Email : ldwoskin@email.uky.edu

Phone :

Fax :

Website :

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References (100)

Title : The vesicular monoamine transporter-2: an important pharmacological target for the discovery of novel therapeutics to treat methamphetamine abuse - Nickell_2014_Adv.Pharmacol_69_71
Author(s) : Nickell JR , Siripurapu KB , Vartak A , Crooks PA , Dwoskin LP
Ref : Advances in Pharmacology , 69 :71 , 2014
Abstract :
PubMedSearch : Nickell_2014_Adv.Pharmacol_69_71
PubMedID: 24484975

Title : Nicotinic receptor antagonists as treatments for nicotine abuse - Crooks_2014_Adv.Pharmacol_69_513
Author(s) : Crooks PA , Bardo MT , Dwoskin LP
Ref : Advances in Pharmacology , 69 :513 , 2014
Abstract :
PubMedSearch : Crooks_2014_Adv.Pharmacol_69_513
PubMedID: 24484986

Title : Potential therapeutic uses of mecamylamine and its stereoisomers - Nickell_2013_Pharmacol.Biochem.Behav_108_28
Author(s) : Nickell JR , Grinevich VP , Siripurapu KB , Smith AM , Dwoskin LP
Ref : Pharmacol Biochem Behav , 108 :28 , 2013
Abstract :
PubMedSearch : Nickell_2013_Pharmacol.Biochem.Behav_108_28
PubMedID: 23603417

Title : Structural modifications to tetrahydropyridine-3-carboxylate esters en route to the discovery of M5-preferring muscarinic receptor orthosteric antagonists - Zheng_2013_J.Med.Chem_56_1693
Author(s) : Zheng G , Smith AM , Huang X , Subramanian KL , Siripurapu KB , Deaciuc A , Zhan CG , Dwoskin LP
Ref : Journal of Medicinal Chemistry , 56 :1693 , 2013
Abstract :
PubMedSearch : Zheng_2013_J.Med.Chem_56_1693
PubMedID: 23379472

Title : Angiotensin AT1 and AT2 receptor antagonists modulate nicotine-evoked [(3)H]dopamine and [(3)H]norepinephrine release - Narayanaswami_2013_Biochem.Pharmacol_86_656
Author(s) : Narayanaswami V , Somkuwar SS , Horton DB , Cassis LA , Dwoskin LP
Ref : Biochemical Pharmacology , 86 :656 , 2013
Abstract :
PubMedSearch : Narayanaswami_2013_Biochem.Pharmacol_86_656
PubMedID: 23831951

Title : The novel small molecule alpha9alpha10 nicotinic acetylcholine receptor antagonist ZZ-204G is analgesic - Holtman_2011_Eur.J.Pharmacol_670_500
Author(s) : Holtman JR , Dwoskin LP , Dowell C , Wala EP , Zhang Z , Crooks PA , McIntosh JM
Ref : European Journal of Pharmacology , 670 :500 , 2011
Abstract :
PubMedSearch : Holtman_2011_Eur.J.Pharmacol_670_500
PubMedID: 21944926

Title : Phenyl ring-substituted lobelane analogs: inhibition of [(3)H]dopamine uptake at the vesicular monoamine transporter-2 - Nickell_2011_J.Pharmacol.Exp.Ther_336_724
Author(s) : Nickell JR , Zheng G , Deaciuc AG , Crooks PA , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 336 :724 , 2011
Abstract :
PubMedSearch : Nickell_2011_J.Pharmacol.Exp.Ther_336_724
PubMedID: 20876747

Title : meso-Transdiene analogs inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release - Horton_2011_J.Pharmacol.Exp.Ther_336_940
Author(s) : Horton DB , Siripurapu KB , Norrholm SD , Culver JP , Hojahmat M , Beckmann JS , Harrod SB , Deaciuc AG , Bardo MT , Crooks PA , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 336 :940 , 2011
Abstract :
PubMedSearch : Horton_2011_J.Pharmacol.Exp.Ther_336_940
PubMedID: 21177475

Title : Novel N-1,2-dihydroxypropyl analogs of lobelane inhibit vesicular monoamine transporter-2 function and methamphetamine-evoked dopamine release - Horton_2011_J.Pharmacol.Exp.Ther_339_286
Author(s) : Horton DB , Siripurapu KB , Zheng G , Crooks PA , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 339 :286 , 2011
Abstract :
PubMedSearch : Horton_2011_J.Pharmacol.Exp.Ther_339_286
PubMedID: 21778282

Title : Design, synthesis and interaction at the vesicular monoamine transporter-2 of lobeline analogs: potential pharmacotherapies for the treatment of psychostimulant abuse - Crooks_2011_Curr.Top.Med.Chem_11_1103
Author(s) : Crooks PA , Zheng G , Vartak AP , Culver JP , Zheng F , Horton DB , Dwoskin LP
Ref : Curr Top Med Chem , 11 :1103 , 2011
Abstract :
PubMedSearch : Crooks_2011_Curr.Top.Med.Chem_11_1103
PubMedID: 21050177

Title : bPiDI: a novel selective alpha6beta2* nicotinic receptor antagonist and preclinical candidate treatment for nicotine abuse - Wooters_2011_Br.J.Pharmacol_163_346
Author(s) : Wooters TE , Smith AM , Pivavarchyk M , Siripurapu KB , McIntosh JM , Zhang Z , Crooks PA , Bardo MT , Dwoskin LP
Ref : British Journal of Pharmacology , 163 :346 , 2011
Abstract :
PubMedSearch : Wooters_2011_Br.J.Pharmacol_163_346
PubMedID: 21232049

Title : Indolizidine (-)-235B' and related structural analogs: discovery of nicotinic receptor antagonists that inhibit nicotine-evoked [3H]dopamine release - Pivavarchyk_2011_Eur.J.Pharmacol_658_132
Author(s) : Pivavarchyk M , Smith AM , Zhang Z , Zhou D , Wang X , Toyooka N , Tsuneki H , Sasaoka T , McIntosh JM , Crooks PA , Dwoskin LP
Ref : European Journal of Pharmacology , 658 :132 , 2011
Abstract :
PubMedSearch : Pivavarchyk_2011_Eur.J.Pharmacol_658_132
PubMedID: 21371454

Title : Novel bis-, tris-, and tetrakis-tertiary amino analogs as antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release - Zhang_2011_Bioorg.Med.Chem.Lett_21_88
Author(s) : Zhang Z , Zheng G , Pivavarchyk M , Deaciuc AG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 21 :88 , 2011
Abstract :
PubMedSearch : Zhang_2011_Bioorg.Med.Chem.Lett_21_88
PubMedID: 21147530

Title : Discovery of non-peptide, small molecule antagonists of alpha9alpha10 nicotinic acetylcholine receptors as novel analgesics for the treatment of neuropathic and tonic inflammatory pain - Zheng_2011_Bioorg.Med.Chem.Lett_21_2476
Author(s) : Zheng G , Zhang Z , Dowell C , Wala E , Dwoskin LP , Holtman JR , McIntosh JM , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 21 :2476 , 2011
Abstract :
PubMedSearch : Zheng_2011_Bioorg.Med.Chem.Lett_21_2476
PubMedID: 21397497

Title : Repeated nicotine administration robustly increases bPiDDB inhibitory potency at alpha6beta2-containing nicotinic receptors mediating nicotine-evoked dopamine release - Smith_2010_Biochem.Pharmacol_80_402
Author(s) : Smith AM , Pivavarchyk M , Wooters TE , Zhang Z , Zheng G , McIntosh JM , Crooks PA , Bardo MT , Dwoskin LP
Ref : Biochemical Pharmacology , 80 :402 , 2010
Abstract :
PubMedSearch : Smith_2010_Biochem.Pharmacol_80_402
PubMedID: 20346923

Title : Lobeline esters as novel ligands for neuronal nicotinic acetylcholine receptors and neurotransmitter transporters - Hojahmat_2010_Bioorg.Med.Chem_18_640
Author(s) : Hojahmat M , Horton DB , Norrholm SD , Miller DK , Grinevich VP , Deaciuc AG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry , 18 :640 , 2010
Abstract :
PubMedSearch : Hojahmat_2010_Bioorg.Med.Chem_18_640
PubMedID: 20036131

Title : Lobelane inhibits methamphetamine-evoked dopamine release via inhibition of the vesicular monoamine transporter-2 - Nickell_2010_J.Pharmacol.Exp.Ther_332_612
Author(s) : Nickell JR , Krishnamurthy S , Norrholm S , Deaciuc G , Siripurapu KB , Zheng G , Crooks PA , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 332 :612 , 2010
Abstract :
PubMedSearch : Nickell_2010_J.Pharmacol.Exp.Ther_332_612
PubMedID: 19855096

Title : Novel bis-2,2,6,6-tetramethylpiperidine (bis-TMP) and bis-mecamylamine antagonists at neuronal nicotinic receptors mediating nicotine-evoked dopamine release - Zhang_2010_Bioorg.Med.Chem.Lett_20_1420
Author(s) : Zhang Z , Pivavarchyk M , Subramanian KL , Deaciuc AG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :1420 , 2010
Abstract :
PubMedSearch : Zhang_2010_Bioorg.Med.Chem.Lett_20_1420
PubMedID: 20079634

Title : The novel pyrrolidine nor-lobelane analog UKCP-110 [cis-2,5-di-(2-phenethyl)-pyrrolidine hydrochloride] inhibits VMAT2 function, methamphetamine-evoked dopamine release, and methamphetamine self-administration in rats - Beckmann_2010_J.Pharmacol.Exp.Ther_335_841
Author(s) : Beckmann JS , Siripurapu KB , Nickell JR , Horton DB , Denehy ED , Vartak A , Crooks PA , Dwoskin LP , Bardo MT
Ref : Journal of Pharmacology & Experimental Therapeutics , 335 :841 , 2010
Abstract :
PubMedSearch : Beckmann_2010_J.Pharmacol.Exp.Ther_335_841
PubMedID: 20805303

Title : Predictive screening model for potential vector-mediated transport of cationic substrates at the blood-brain barrier choline transporter - Geldenhuys_2010_Bioorg.Med.Chem.Lett_20_870
Author(s) : Geldenhuys WJ , Manda VK , Mittapalli RK , Van der Schyf CJ , Crooks PA , Dwoskin LP , Allen DD , Lockman PR
Ref : Bioorganic & Medicinal Chemistry Lett , 20 :870 , 2010
Abstract :
PubMedSearch : Geldenhuys_2010_Bioorg.Med.Chem.Lett_20_870
PubMedID: 20053562

Title : Nicotinic receptor-based therapeutics and candidates for smoking cessation - Dwoskin_2009_Biochem.Pharmacol_78(7)_732
Author(s) : Dwoskin LP , Smith AM , Wooters TE , Zhang Z , Crooks PA , Bardo MT
Ref : Biochemical Pharmacology , 78 :732 , 2009
Abstract :
PubMedSearch : Dwoskin_2009_Biochem.Pharmacol_78(7)_732
PubMedID: 19523455

Title : Mecamylamine, dihydro-beta-erythroidine, and dextromethorphan block conditioned responding evoked by the conditional stimulus effects of nicotine - Struthers_2009_Pharmacol.Biochem.Behav_94_319
Author(s) : Struthers AM , Wilkinson JL , Dwoskin LP , Crooks PA , Bevins RA
Ref : Pharmacol Biochem Behav , 94 :319 , 2009
Abstract :
PubMedSearch : Struthers_2009_Pharmacol.Biochem.Behav_94_319
PubMedID: 19778551

Title : The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices - Smith_2009_Biochem.Pharmacol_78(7)_889
Author(s) : Smith AM , Dhawan GK , Zhang Z , Siripurapu KB , Crooks PA , Dwoskin LP
Ref : Biochemical Pharmacology , 78 :889 , 2009
Abstract :
PubMedSearch : Smith_2009_Biochem.Pharmacol_78(7)_889
PubMedID: 19631612

Title : Poster: GZ556A and ZZ204G are novel small molecule antagonists of alpha9alpha10 nAChRs and are analgesic in rats -
Author(s) : McIntosh JM , Dwoskin LP , Crooks PA , Holtman Jr JR
Ref : Biochemical Pharmacology , 78 :921 , 2009
PubMedID:

Title : Selective inhibition of acetylcholine-evoked responses of alpha7 neuronal nicotinic acetylcholine receptors by novel tris- and tetrakis-azaaromatic quaternary ammonium antagonists - Lopez-Hernandez_2009_Mol.Pharmacol_76_652
Author(s) : Lopez-Hernandez GY , Thinschmidt JS , Zheng G , Zhang Z , Crooks PA , Dwoskin LP , Papke RL
Ref : Molecular Pharmacology , 76 :652 , 2009
Abstract :
PubMedSearch : Lopez-Hernandez_2009_Mol.Pharmacol_76_652
PubMedID: 19556356

Title : Targeting nicotinic receptor antagonists as novel pharmacotherapies for tobacco dependence and relapse -
Author(s) : Dwoskin LP , Bardo MT
Ref : Neuropsychopharmacology , 34 :244 , 2009
PubMedID: 19079069

Title : Targeting reward-relevant nicotinic receptors in the discovery of novel pharmacotherapeutic agents to treat tobacco dependence -
Author(s) : Dwoskin LP , Pivavarchyk M , Joyce BM , Neugebauer NM , Zheng G , Zhang Z , Bardo MT , Crooks PA
Ref : Nebr Symp Motiv , 55 :31 , 2009
PubMedID: 19013938

Title : First-Principles Determination of Molecular Conformations of Indolizidine (-)-235B' in Solution - Zheng_2009_Theor.Chem.Acc_124_269
Author(s) : Zheng F , Dwoskin LP , Crooks PA , Zhan CG
Ref : Theor Chem Acc , 124 :269 , 2009
Abstract :
PubMedSearch : Zheng_2009_Theor.Chem.Acc_124_269
PubMedID: 20161506

Title : QSAR study on maximal inhibition (Imax) of quaternary ammonium antagonists for S-(-)-nicotine-evoked dopamine release from dopaminergic nerve terminals in rat striatum - Zheng_2009_Bioorg.Med.Chem_17_4477
Author(s) : Zheng F , McConnell MJ , Zhan CG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry , 17 :4477 , 2009
Abstract :
PubMedSearch : Zheng_2009_Bioorg.Med.Chem_17_4477
PubMedID: 19477134

Title : Computational neural network analysis of the affinity of N-n-alkylnicotinium salts for the alpha4beta2* nicotinic acetylcholine receptor - Zheng_2009_J.Enzyme.Inhib.Med.Chem_24_157
Author(s) : Zheng F , Zheng G , Deaciuc AG , Zhan CG , Dwoskin LP , Crooks PA
Ref : J Enzyme Inhib Med Chem , 24 :157 , 2009
Abstract :
PubMedSearch : Zheng_2009_J.Enzyme.Inhib.Med.Chem_24_157
PubMedID: 18629679

Title : Nicotinic receptor activation increases [3H]dopamine uptake and cell surface expression of dopamine transporters in rat prefrontal cortex - Zhu_2009_J.Pharmacol.Exp.Ther_328_931
Author(s) : Zhu J , Apparsundaram S , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 328 :931 , 2009
Abstract :
PubMedSearch : Zhu_2009_J.Pharmacol.Exp.Ther_328_931
PubMedID: 19088301

Title : Extending the analysis of nicotinic receptor antagonists with the study of alpha6 nicotinic receptor subunit chimeras - Papke_2008_Neuropharmacol_54_1189
Author(s) : Papke RL , Dwoskin LP , Crooks PA , Zheng G , Zhang Z , McIntosh JM , Stokes C
Ref : Neuropharmacology , 54 :1189 , 2008
Abstract :
PubMedSearch : Papke_2008_Neuropharmacol_54_1189
PubMedID: 18448138

Title : Tetrakis-azaaromatic quaternary ammonium salts: novel subtype-selective antagonists at neuronal nicotinic receptors that mediate nicotine-evoked dopamine release - Zhang_2008_Bioorg.Med.Chem.Lett_18_5753
Author(s) : Zhang Z , Zheng G , Pivavarchyk M , Deaciuc AG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 18 :5753 , 2008
Abstract :
PubMedSearch : Zhang_2008_Bioorg.Med.Chem.Lett_18_5753
PubMedID: 18851914

Title : The novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide decreases nicotine-induced dopamine metabolism in rat nucleus accumbens - Rahman_2008_Eur.J.Pharmacol_601_103
Author(s) : Rahman S , Neugebauer NM , Zhang Z , Crooks PA , Dwoskin LP , Bardo MT
Ref : European Journal of Pharmacology , 601 :103 , 2008
Abstract :
PubMedSearch : Rahman_2008_Eur.J.Pharmacol_601_103
PubMedID: 19000671

Title : N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity - Dwoskin_2008_J.Pharmacol.Exp.Ther_326_563
Author(s) : Dwoskin LP , Wooters TE , Sumithran SP , Siripurapu KB , Joyce BM , Lockman PR , Manda VK , Ayers JT , Zhang Z , Deaciuc AG , McIntosh JM , Crooks PA , Bardo MT
Ref : Journal of Pharmacology & Experimental Therapeutics , 326 :563 , 2008
Abstract :
PubMedSearch : Dwoskin_2008_J.Pharmacol.Exp.Ther_326_563
PubMedID: 18460644

Title : Carrier-mediated transport of the quaternary ammonium neuronal nicotinic receptor antagonist n,n'-dodecylbispicolinium dibromide at the blood-brain barrier - Lockman_2008_J.Pharmacol.Exp.Ther_324_244
Author(s) : Lockman PR , Manda VK , Geldenhuys WJ , Mittapalli RK , Thomas F , Albayati ZF , Crooks PA , Dwoskin LP , Allen DD
Ref : Journal of Pharmacology & Experimental Therapeutics , 324 :244 , 2008
Abstract :
PubMedSearch : Lockman_2008_J.Pharmacol.Exp.Ther_324_244
PubMedID: 17921191

Title : Region-specific effects of N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide on nicotine-induced increase in extracellular dopamine in vivo - Rahman_2008_Br.J.Pharmacol_153_792
Author(s) : Rahman S , Zhang Z , Papke RL , Crooks PA , Dwoskin LP , Bardo MT
Ref : British Journal of Pharmacology , 153 :792 , 2008
Abstract :
PubMedSearch : Rahman_2008_Br.J.Pharmacol_153_792
PubMedID: 18059317

Title : Pharmacokinetics of the novel nicotinic receptor antagonist N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide in the rat - Albayati_2008_Drug.Metab.Dispos_36_2024
Author(s) : Albayati ZA , Dwoskin LP , Crooks PA
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 36 :2024 , 2008
Abstract :
PubMedSearch : Albayati_2008_Drug.Metab.Dispos_36_2024
PubMedID: 18617603

Title : Discovery of a novel nicotinic receptor antagonist for the treatment of nicotine addiction: 1-(3-Picolinium)-12-triethylammonium-dodecane dibromide (TMPD) - Dwoskin_2007_Biochem.Pharmacol_74(8)_1271
Author(s) : Dwoskin LP , Joyce BM , Zheng G , Neugebauer NM , Manda VK , Lockman P , Papke RL , Bardo MT , Crooks PA
Ref : Biochemical Pharmacology , 74 :1271 , 2007
Abstract :
PubMedSearch : Dwoskin_2007_Biochem.Pharmacol_74(8)_1271
PubMedID: 17727820

Title : The pharmacological activity of nicotine and nornicotine on nAChRs subtypes: relevance to nicotine dependence and drug discovery - Papke_2007_J.Neurochem_101_160
Author(s) : Papke RL , Dwoskin LP , Crooks PA
Ref : Journal of Neurochemistry , 101 :160 , 2007
Abstract :
PubMedSearch : Papke_2007_J.Neurochem_101_160
PubMedID: 17241116

Title : The effects of a novel nicotinic receptor antagonist N,N-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB) on acute and repeated nicotine-induced increases in extracellular dopamine in rat nucleus accumbens - Rahman_2007_Neuropharmacol_52_755
Author(s) : Rahman S , Neugebauer NM , Zhang Z , Crooks PA , Dwoskin LP , Bardo MT
Ref : Neuropharmacology , 52 :755 , 2007
Abstract :
PubMedSearch : Rahman_2007_Neuropharmacol_52_755
PubMedID: 17097117

Title : Computational neural network analysis of the affinity of lobeline and tetrabenazine analogs for the vesicular monoamine transporter-2 - Zheng_2007_Bioorg.Med.Chem_15_2975
Author(s) : Zheng F , Zheng G , Deaciuc AG , Zhan CG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry , 15 :2975 , 2007
Abstract :
PubMedSearch : Zheng_2007_Bioorg.Med.Chem_15_2975
PubMedID: 17331733

Title : Tris-azaaromatic quaternary ammonium salts: Novel templates as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release - Zheng_2007_Bioorg.Med.Chem.Lett_17_6701
Author(s) : Zheng G , Sumithran SP , Deaciuc AG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 17 :6701 , 2007
Abstract :
PubMedSearch : Zheng_2007_Bioorg.Med.Chem.Lett_17_6701
PubMedID: 17977723

Title : Bis-azaaromatic quaternary ammonium salts as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release: An investigation of binding conformation - Zheng_2007_Bioorg.Med.Chem.Lett_17_6734
Author(s) : Zheng G , Zhang Z , Pivavarchyk M , Deaciuc AG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 17 :6734 , 2007
Abstract :
PubMedSearch : Zheng_2007_Bioorg.Med.Chem.Lett_17_6734
PubMedID: 18029180

Title : Individual differences in response to novelty predict prefrontal cortex dopamine transporter function and cell surface expression - Zhu_2007_Eur.J.Neurosci_26_717
Author(s) : Zhu J , Bardo MT , Bruntz RC , Stairs DJ , Dwoskin LP
Ref : European Journal of Neuroscience , 26 :717 , 2007
Abstract :
PubMedSearch : Zhu_2007_Eur.J.Neurosci_26_717
PubMedID: 17651428

Title : Nicotine increases dopamine clearance in medial prefrontal cortex in rats raised in an enriched environment - Zhu_2007_J.Neurochem_103_2575
Author(s) : Zhu J , Bardo MT , Green TA , Wedlund PJ , Dwoskin LP
Ref : Journal of Neurochemistry , 103 :2575 , 2007
Abstract :
PubMedSearch : Zhu_2007_J.Neurochem_103_2575
PubMedID: 17953677

Title : Nornicotine inhibition of dopamine transporter function in striatum via nicotinic receptor activation - Middleton_2007_Synapse_61_157
Author(s) : Middleton LS , Crooks PA , Wedlund PJ , Cass WA , Dwoskin LP
Ref : Synapse , 61 :157 , 2007
Abstract :
PubMedSearch : Middleton_2007_Synapse_61_157
PubMedID: 17146768

Title : N, N -disubstituted piperazines and homopiperazines: synthesis and affinities at alpha4beta2* and alpha7* neuronal nicotinic acetylcholine receptors - Chen_2006_J.Enzyme.Inhib.Med.Chem_21_667
Author(s) : Chen J , Deaciuc AG , Dwoskin LP , Crooks PA , Bai D
Ref : J Enzyme Inhib Med Chem , 21 :667 , 2006
Abstract :
PubMedSearch : Chen_2006_J.Enzyme.Inhib.Med.Chem_21_667
PubMedID: 17252939

Title : Modeling subtype-selective agonists binding with alpha4beta2 and alpha7 nicotinic acetylcholine receptors: effects of local binding and long-range electrostatic interactions - Huang_2006_J.Med.Chem_49_7661
Author(s) : Huang X , Zheng F , Chen X , Crooks PA , Dwoskin LP , Zhan CG
Ref : Journal of Medicinal Chemistry , 49 :7661 , 2006
Abstract :
PubMedSearch : Huang_2006_J.Med.Chem_49_7661
PubMedID: 17181149

Title : Review of the pharmacology and clinical profile of bupropion, an antidepressant and tobacco use cessation agent - Dwoskin_2006_CNS.Drug.Rev_12_178
Author(s) : Dwoskin LP , Rauhut AS , King-Pospisil KA , Bardo MT
Ref : CNS Drug Rev , 12 :178 , 2006
Abstract :
PubMedSearch : Dwoskin_2006_CNS.Drug.Rev_12_178
PubMedID: 17227286

Title : QSAR modeling of mono- and bis-quaternary ammonium salts that act as antagonists at neuronal nicotinic acetylcholine receptors mediating dopamine release - Zheng_2006_Bioorg.Med.Chem_14_3017
Author(s) : Zheng F , Bayram E , Sumithran SP , Ayers JT , Zhan CG , Schmitt JD , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry , 14 :3017 , 2006
Abstract :
PubMedSearch : Zheng_2006_Bioorg.Med.Chem_14_3017
PubMedID: 16431111

Title : Des-keto lobeline analogs with increased potency and selectivity at dopamine and serotonin transporters - Zheng_2006_Bioorg.Med.Chem.Lett_16_5018
Author(s) : Zheng G , Horton DB , Deaciuc AG , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 16 :5018 , 2006
Abstract :
PubMedSearch : Zheng_2006_Bioorg.Med.Chem.Lett_16_5018
PubMedID: 16905316

Title : Effect of a novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide, on nicotine self-administration and hyperactivity in rats - Neugebauer_2006_Psychopharmacology.(Berl)_184_426
Author(s) : Neugebauer NM , Zhang Z , Crooks PA , Dwoskin LP , Bardo MT
Ref : Psychopharmacology (Berl) , 184 :426 , 2006
Abstract :
PubMedSearch : Neugebauer_2006_Psychopharmacology.(Berl)_184_426
PubMedID: 16220336

Title : Introduction of unsaturation into the N-n-alkyl chain of the nicotinic receptor antagonists, NONI and NDNI: effect on affinity and selectivity - Sumithran_2005_AAPS.J_7_E201
Author(s) : Sumithran SP , Crooks PA , Xu R , Zhu J , Deaciuc AG , Wilkins LH , Dwoskin LP
Ref : AAPS J , 7 :E201 , 2005
Abstract :
PubMedSearch : Sumithran_2005_AAPS.J_7_E201
PubMedID: 16146341

Title : Modeling multiple species of nicotine and deschloroepibatidine interacting with alpha4beta2 nicotinic acetylcholine receptor: from microscopic binding to phenomenological binding affinity - Huang_2005_J.Am.Chem.Soc_127_14401
Author(s) : Huang X , Zheng F , Crooks PA , Dwoskin LP , Zhan CG
Ref : Journal of the American Chemical Society , 127 :14401 , 2005
Abstract :
PubMedSearch : Huang_2005_J.Am.Chem.Soc_127_14401
PubMedID: 16218635

Title : The characterization of a novel rigid nicotine analog with alpha7-selective nAChR agonist activity and modulation of agonist properties by boron inclusion - Papke_2005_Bioorg.Med.Chem.Lett_15_3874
Author(s) : Papke RL , Zheng G , Horenstein NA , Dwoskin LP , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :3874 , 2005
Abstract :
PubMedSearch : Papke_2005_Bioorg.Med.Chem.Lett_15_3874
PubMedID: 16005216

Title : Identification and synthesis of novel alkaloids from the root system of Nicotiana tabacum: affinity for neuronal nicotinic acetylcholine receptors - Wei_2005_Life.Sci_78_495
Author(s) : Wei X , Sumithran SP , Deaciuc AG , Burton HR , Bush LP , Dwoskin LP , Crooks PA
Ref : Life Sciences , 78 :495 , 2005
Abstract :
PubMedSearch : Wei_2005_Life.Sci_78_495
PubMedID: 16197964

Title : N-n-alkylnicotinium analogs, a novel class of antagonists at alpha 4 beta 2* nicotinic acetylcholine receptors: inhibition of S(-)-nicotine-evoked 86Rb+ efflux from rat thalamic synaptosomes - Wilkins_2005_AAPS.J_7_E922
Author(s) : Wilkins LH, Jr. , Miller DK , Ayers JT , Crooks PA , Dwoskin LP
Ref : AAPS J , 7 :E922 , 2005
Abstract :
PubMedSearch : Wilkins_2005_AAPS.J_7_E922
PubMedID: 16594645

Title : Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands - Zheng_2005_Bioorg.Med.Chem.Lett_15_4463
Author(s) : Zheng G , Dwoskin LP , Deaciuc AG , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 15 :4463 , 2005
Abstract :
PubMedSearch : Zheng_2005_Bioorg.Med.Chem.Lett_15_4463
PubMedID: 16112864

Title : Defunctionalized lobeline analogues: structure-activity of novel ligands for the vesicular monoamine transporter - Zheng_2005_J.Med.Chem_48_5551
Author(s) : Zheng G , Dwoskin LP , Deaciuc AG , Norrholm SD , Crooks PA
Ref : Journal of Medicinal Chemistry , 48 :5551 , 2005
Abstract :
PubMedSearch : Zheng_2005_J.Med.Chem_48_5551
PubMedID: 16107155

Title : Lobelane analogues as novel ligands for the vesicular monoamine transporter-2 - Zheng_2005_Bioorg.Med.Chem_13_3899
Author(s) : Zheng G , Dwoskin LP , Deaciuc AG , Zhu J , Jones MD , Crooks PA
Ref : Bioorganic & Medicinal Chemistry , 13 :3899 , 2005
Abstract :
PubMedSearch : Zheng_2005_Bioorg.Med.Chem_13_3899
PubMedID: 15911306

Title : Tolerance does not develop to the decrease in nicotine self-administration produced by repeated bupropion administration - Rauhut_2005_Nicotine.Tob.Res_7_901
Author(s) : Rauhut AS , Dwoskin LP , Bardo MT
Ref : Nicotine Tob Res , 7 :901 , 2005
Abstract :
PubMedSearch : Rauhut_2005_Nicotine.Tob.Res_7_901
PubMedID: 16298725

Title : Molecular modeling of mono- and bis-quaternary ammonium salts as ligands at the alpha4beta2 nicotinic acetylcholine receptor subtype using nonlinear techniques - Ayers_2005_AAPS.J_7_E678
Author(s) : Ayers JT , Clauset A , Schmitt JD , Dwoskin LP , Crooks PA
Ref : AAPS J , 7 :E678 , 2005
Abstract :
PubMedSearch : Ayers_2005_AAPS.J_7_E678
PubMedID: 16353944

Title : A general procedure for the enantioselective synthesis of the minor tobacco alkaloids nornicotine, anabasine, and anatabine - Ayers_2005_AAPS.J_7_E752
Author(s) : Ayers JT , Xu R , Dwoskin LP , Crooks PA
Ref : AAPS J , 7 :E752 , 2005
Abstract :
PubMedSearch : Ayers_2005_AAPS.J_7_E752
PubMedID: 16353951

Title : Development of subtype-selective ligands as antagonists at nicotinic receptors mediating nicotine-evoked dopamine release - Crooks_2004_Bioorg.Med.Chem.Lett_14_1869
Author(s) : Crooks PA , Ayers JT , Xu R , Sumithran SP , Grinevich VP , Wilkins LH , Deaciuc AG , Allen DD , Dwoskin LP
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1869 , 2004
Abstract :
PubMedSearch : Crooks_2004_Bioorg.Med.Chem.Lett_14_1869
PubMedID: 15050618

Title : Subtype-selective nicotinic receptor antagonists: potential as tobacco use cessation agents - Dwoskin_2004_Bioorg.Med.Chem.Lett_14_1863
Author(s) : Dwoskin LP , Sumithran SP , Zhu J , Deaciuc AG , Ayers JT , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 14 :1863 , 2004
Abstract :
PubMedSearch : Dwoskin_2004_Bioorg.Med.Chem.Lett_14_1863
PubMedID: 15050617

Title : Nicotinic receptor modulation of dopamine transporter function in rat striatum and medial prefrontal cortex - Middleton_2004_J.Pharmacol.Exp.Ther_308_367
Author(s) : Middleton LS , Cass WA , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 308 :367 , 2004
Abstract :
PubMedSearch : Middleton_2004_J.Pharmacol.Exp.Ther_308_367
PubMedID: 14563785

Title : Lobeline analogs with enhanced affinity and selectivity for plasmalemma and vesicular monoamine transporters - Miller_2004_J.Pharmacol.Exp.Ther_310_1035
Author(s) : Miller DK , Crooks PA , Zheng G , Grinevich VP , Norrholm SD , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 310 :1035 , 2004
Abstract :
PubMedSearch : Miller_2004_J.Pharmacol.Exp.Ther_310_1035
PubMedID: 15121762

Title : Effects of environmental enrichment on behavior and dopamine transporter function in medial prefrontal cortex in adult rats prenatally treated with cocaine - Neugebauer_2004_Brain.Res.Dev.Brain.Res_153_213
Author(s) : Neugebauer NM , Cunningham ST , Zhu J , Bryant RI , Middleton LS , Dwoskin LP
Ref : Brain Research Developmental Brain Research , 153 :213 , 2004
Abstract :
PubMedSearch : Neugebauer_2004_Brain.Res.Dev.Brain.Res_153_213
PubMedID: 15527889

Title : Lobeline does not serve as a reinforcer in rats - Harrod_2003_Psychopharmacology.(Berl)_165_397
Author(s) : Harrod SB , Dwoskin LP , Green TA , Gehrke BJ , Bardo MT
Ref : Psychopharmacology (Berl) , 165 :397 , 2003
Abstract :
PubMedSearch : Harrod_2003_Psychopharmacology.(Berl)_165_397
PubMedID: 12459929

Title : N,N-disubstituted piperazines: synthesis and affinities at alpha4beta2(*) and alpha7(*) neuronal nicotinic acetylcholine receptors - Chen_2003_Bioorg.Med.Chem.Lett_13_97
Author(s) : Chen J , Norrholm S , Dwoskin LP , Crooks PA , Bai D
Ref : Bioorganic & Medicinal Chemistry Lett , 13 :97 , 2003
Abstract :
PubMedSearch : Chen_2003_Bioorg.Med.Chem.Lett_13_97
PubMedID: 12467625

Title : N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonists: interaction with alpha4beta2* and alpha7* neuronal nicotinic receptors - Wilkins_2003_J.Pharmacol.Exp.Ther_304_400
Author(s) : Wilkins LH, Jr. , Grinevich VP , Ayers JT , Crooks PA , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 304 :400 , 2003
Abstract :
PubMedSearch : Wilkins_2003_J.Pharmacol.Exp.Ther_304_400
PubMedID: 12490617

Title : Effect of bupropion on nicotine self-administration in rats - Rauhut_2003_Psychopharmacology.(Berl)_169_1
Author(s) : Rauhut AS , Neugebauer N , Dwoskin LP , Bardo MT
Ref : Psychopharmacology (Berl) , 169 :1 , 2003
Abstract :
PubMedSearch : Rauhut_2003_Psychopharmacology.(Berl)_169_1
PubMedID: 12811464

Title : N-n-alkylpyridinium analogs, a novel class of nicotinic receptor antagonists: selective inhibition of nicotine-evoked [3H] dopamine overflow from superfused rat striatal slices - Grinevich_2003_J.Pharmacol.Exp.Ther_306_1011
Author(s) : Grinevich VP , Crooks PA , Sumithran SP , Haubner AJ , Ayers JT , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 306 :1011 , 2003
Abstract :
PubMedSearch : Grinevich_2003_J.Pharmacol.Exp.Ther_306_1011
PubMedID: 12766255

Title : Lobeline attenuates locomotor stimulation induced by repeated nicotine administration in rats - Miller_2003_Pharmacol.Biochem.Behav_74_279
Author(s) : Miller DK , Harrod SB , Green TA , Wong MY , Bardo MT , Dwoskin LP
Ref : Pharmacol Biochem Behav , 74 :279 , 2003
Abstract :
PubMedSearch : Miller_2003_Pharmacol.Biochem.Behav_74_279
PubMedID: 12479946

Title : N-n-alkylnicotinium analogs, a novel class of nicotinic receptor antagonist: inhibition of S(-)-nicotine-evoked [(3)H]dopamine overflow from superfused rat striatal slices - Wilkins_2002_J.Pharmacol.Exp.Ther_301_1088
Author(s) : Wilkins LH, Jr. , Haubner A , Ayers JT , Crooks PA , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 301 :1088 , 2002
Abstract :
PubMedSearch : Wilkins_2002_J.Pharmacol.Exp.Ther_301_1088
PubMedID: 12023541

Title : A novel mechanism of action and potential use for lobeline as a treatment for psychostimulant abuse - Dwoskin_2002_Biochem.Pharmacol_63_89
Author(s) : Dwoskin LP , Crooks PA
Ref : Biochemical Pharmacology , 63 :89 , 2002
Abstract :
PubMedSearch : Dwoskin_2002_Biochem.Pharmacol_63_89
PubMedID: 11841781

Title : Reboxetine: attenuation of intravenous nicotine self-administration in rats - Rauhut_2002_J.Pharmacol.Exp.Ther_303_664
Author(s) : Rauhut AS , Mullins SN , Dwoskin LP , Bardo MT
Ref : Journal of Pharmacology & Experimental Therapeutics , 303 :664 , 2002
Abstract :
PubMedSearch : Rauhut_2002_J.Pharmacol.Exp.Ther_303_664
PubMedID: 12388649

Title : bis-Azaaromatic quaternary ammonium analogues: ligands for alpha4beta2* and alpha7* subtypes of neuronal nicotinic receptors - Ayers_2002_Bioorg.Med.Chem.Lett_12_3067
Author(s) : Ayers JT , Dwoskin LP , Deaciuc AG , Grinevich VP , Zhu J , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 12 :3067 , 2002
Abstract :
PubMedSearch : Ayers_2002_Bioorg.Med.Chem.Lett_12_3067
PubMedID: 12372503

Title : Bupropion inhibits nicotine-evoked [(3)H]overflow from rat striatal slices preloaded with [(3)H]dopamine and from rat hippocampal slices preloaded with [(3)H]norepinephrine - Miller_2002_J.Pharmacol.Exp.Ther_302_1113
Author(s) : Miller DK , Sumithran SP , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 302 :1113 , 2002
Abstract :
PubMedSearch : Miller_2002_J.Pharmacol.Exp.Ther_302_1113
PubMedID: 12183670

Title : Reboxetine: functional inhibition of monoamine transporters and nicotinic acetylcholine receptors - Miller_2002_J.Pharmacol.Exp.Ther_302_687
Author(s) : Miller DK , Wong EH , Chesnut MD , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 302 :687 , 2002
Abstract :
PubMedSearch : Miller_2002_J.Pharmacol.Exp.Ther_302_687
PubMedID: 12130733

Title : Lobeline attenuates d-methamphetamine self-administration in rats - Harrod_2001_J.Pharmacol.Exp.Ther_298_172
Author(s) : Harrod SB , Dwoskin LP , Crooks PA , Klebaur JE , Bardo MT
Ref : Journal of Pharmacology & Experimental Therapeutics , 298 :172 , 2001
Abstract :
PubMedSearch : Harrod_2001_J.Pharmacol.Exp.Ther_298_172
PubMedID: 11408539

Title : Pharmacological differences between immunoisolated native brain and heterologously expressed rat alpha4beta2 nicotinic receptors - Truong_2001_Brain.Res.Mol.Brain.Res_96_68
Author(s) : Truong A , Xing X , Forsayeth JR , Dwoskin LP , Crooks PA , Cohen BN
Ref : Brain Research Mol Brain Res , 96 :68 , 2001
Abstract :
PubMedSearch : Truong_2001_Brain.Res.Mol.Brain.Res_96_68
PubMedID: 11731010

Title : Neuronal nicotinic acetylcholine receptor binding affinities of boron-containing nicotine analogues - Xu_2001_Bioorg.Med.Chem.Lett_11_1245
Author(s) : Xu R , Dwoskin LP , Grinevich VP , Deaciuc G , Crooks PA
Ref : Bioorganic & Medicinal Chemistry Lett , 11 :1245 , 2001
Abstract :
PubMedSearch : Xu_2001_Bioorg.Med.Chem.Lett_11_1245
PubMedID: 11354387

Title : Competitive neuronal nicotinic receptor antagonists: a new direction for drug discovery - Dwoskin_2001_J.Pharmacol.Exp.Ther_298_395
Author(s) : Dwoskin LP , Crooks PA
Ref : Journal of Pharmacology & Experimental Therapeutics , 298 :395 , 2001
Abstract :
PubMedSearch : Dwoskin_2001_J.Pharmacol.Exp.Ther_298_395
PubMedID: 11454899

Title : Nornicotine, a nicotine metabolite and tobacco alkaloid: desensitization of nicotinic receptor-stimulated dopamine release from rat striatum - Dwoskin_2001_Eur.J.Pharmacol_428_69
Author(s) : Dwoskin LP , Teng LH , Crooks PA
Ref : European Journal of Pharmacology , 428 :69 , 2001
Abstract :
PubMedSearch : Dwoskin_2001_Eur.J.Pharmacol_428_69
PubMedID: 11779039

Title : Once weekly administration of nicotine produces long-lasting locomotor sensitization in rats via a nicotinic receptor-mediated mechanism - Miller_2001_Psychopharmacology.(Berl)_156_469
Author(s) : Miller DK , Wilkins LH , Bardo MT , Crooks PA , Dwoskin LP
Ref : Psychopharmacology (Berl) , 156 :469 , 2001
Abstract :
PubMedSearch : Miller_2001_Psychopharmacology.(Berl)_156_469
PubMedID: 11498725

Title : Contributory role for nornicotine in nicotine neuropharmacology: nornicotine-evoked [3H]dopamine overflow from rat nucleus accumbens slices - Green_2001_Biochem.Pharmacol_62_1597
Author(s) : Green TA , Crooks PA , Bardo MT , Dwoskin LP
Ref : Biochemical Pharmacology , 62 :1597 , 2001
Abstract :
PubMedSearch : Green_2001_Biochem.Pharmacol_62_1597
PubMedID: 11755112

Title : Lobeline inhibits nicotine-evoked [(3)H]dopamine overflow from rat striatal slices and nicotine-evoked (86)Rb(+) efflux from thalamic synaptosomes - Miller_2000_Neuropharmacol_39_2654
Author(s) : Miller DK , Crooks PA , Dwoskin LP
Ref : Neuropharmacology , 39 :2654 , 2000
Abstract :
PubMedSearch : Miller_2000_Neuropharmacol_39_2654
PubMedID: 11044735

Title : Nornicotine pretreatment decreases intravenous nicotine self-administration in rats - Green_2000_Psychopharmacology.(Berl)_152_289
Author(s) : Green TA , Phillips SB , Crooks PA , Dwoskin LP , Bardo MT
Ref : Psychopharmacology (Berl) , 152 :289 , 2000
Abstract :
PubMedSearch : Green_2000_Psychopharmacology.(Berl)_152_289
PubMedID: 11105939

Title : (S)-(-)-Cotinine, the major brain metabolite of nicotine, stimulates nicotinic receptors to evoke [3H]dopamine release from rat striatal slices in a calcium-dependent manner - Dwoskin_1999_J.Pharmacol.Exp.Ther_288_905
Author(s) : Dwoskin LP , Teng L , Buxton ST , Crooks PA
Ref : Journal of Pharmacology & Experimental Therapeutics , 288 :905 , 1999
Abstract :
PubMedSearch : Dwoskin_1999_J.Pharmacol.Exp.Ther_288_905
PubMedID: 10027825

Title : Acute and chronic effects of nornicotine on locomotor activity in rats: altered response to nicotine - Dwoskin_1999_Psychopharmacology.(Berl)_145_442
Author(s) : Dwoskin LP , Crooks PA , Teng L , Green TA , Bardo MT
Ref : Psychopharmacology (Berl) , 145 :442 , 1999
Abstract :
PubMedSearch : Dwoskin_1999_Psychopharmacology.(Berl)_145_442
PubMedID: 10460322

Title : Development of a novel class of subtype-selective nicotinic receptor antagonist: pyridine-N-substituted nicotine analogs -
Author(s) : Dwoskin LP , Wilkins LH , Pauly JR , Crooks PA
Ref : Annals of the New York Academy of Sciences , 868 :617 , 1999
PubMedID: 10414342

Title : Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2'-(14)C]nicotine - Ghosheh_1999_Drug.Metab.Dispos_27_1448
Author(s) : Ghosheh O , Dwoskin LP , Li WK , Crooks PA
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 27 :1448 , 1999
Abstract :
PubMedSearch : Ghosheh_1999_Drug.Metab.Dispos_27_1448
PubMedID: 10570026

Title : Pharmacological similarities between native brain and heterologously expressed alpha4beta2 nicotinic receptors - Shafaee_1999_Br.J.Pharmacol_128_1291
Author(s) : Shafaee N , Houng M , Truong A , Viseshakul N , Figl A , Sandhu S , Forsayeth JR , Dwoskin LP , Crooks PA , Cohen BN
Ref : British Journal of Pharmacology , 128 :1291 , 1999
Abstract :
PubMedSearch : Shafaee_1999_Br.J.Pharmacol_128_1291
PubMedID: 10578144

Title : Lobeline displaces [3H]dihydrotetrabenazine binding and releases [3H]dopamine from rat striatal synaptic vesicles: comparison with d-amphetamine - Teng_1998_J.Neurochem_71_258
Author(s) : Teng L , Crooks PA , Dwoskin LP
Ref : Journal of Neurochemistry , 71 :258 , 1998
Abstract :
PubMedSearch : Teng_1998_J.Neurochem_71_258
PubMedID: 9648873

Title : Nicotinic-receptor mediation of S(-)nornicotine-evoked -3H-overflow from rat striatal slices preloaded with -3H-dopamine - Teng_1997_J.Pharmacol.Exp.Ther_283_778
Author(s) : Teng L , Crooks PA , Buxton ST , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 283 :778 , 1997
Abstract :
PubMedSearch : Teng_1997_J.Pharmacol.Exp.Ther_283_778
PubMedID: 9353398

Title : Lobeline and nicotine evoke [3H]overflow from rat striatal slices preloaded with [3H]dopamine: differential inhibition of synaptosomal and vesicular [3H]dopamine uptake - Teng_1997_J.Pharmacol.Exp.Ther_280_1432
Author(s) : Teng L , Crooks PA , Sonsalla PK , Dwoskin LP
Ref : Journal of Pharmacology & Experimental Therapeutics , 280 :1432 , 1997
Abstract :
PubMedSearch : Teng_1997_J.Pharmacol.Exp.Ther_280_1432
PubMedID: 9067333

Title : Contribution of CNS nicotine metabolites to the neuropharmacological effects of nicotine and tobacco smoking - Crooks_1997_Biochem.Pharmacol_54_743
Author(s) : Crooks PA , Dwoskin LP
Ref : Biochemical Pharmacology , 54 :743 , 1997
Abstract :
PubMedSearch : Crooks_1997_Biochem.Pharmacol_54_743
PubMedID: 9353128

Title : (-)-Nornicotine partially substitutes for (+)-amphetamine in a drug discrimination paradigm in rats - Bardo_1997_Pharmacol.Biochem.Behav_58_1083
Author(s) : Bardo MT , Bevins RA , Klebaur JE , Crooks PA , Dwoskin LP
Ref : Pharmacol Biochem Behav , 58 :1083 , 1997
Abstract :
PubMedSearch : Bardo_1997_Pharmacol.Biochem.Behav_58_1083
PubMedID: 9408217