Title : Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13 - Aggarwal_2017_Cell_170_249 |
Author(s) : Aggarwal A , Parai MK , Shetty N , Wallis D , Woolhiser L , Hastings C , Dutta NK , Galaviz S , Dhakal RC , Shrestha R , Wakabayashi S , Walpole C , Matthews D , Floyd D , Scullion P , Riley J , Epemolu O , Norval S , Snavely T , Robertson GT , Rubin EJ , Ioerger TR , Sirgel FA , van der Merwe R , van Helden PD , Keller P , Bottger EC , Karakousis PC , Lenaerts AJ , Sacchettini JC |
Ref : Cell , 170 :249 , 2017 |
Abstract : |
PubMedSearch : Aggarwal_2017_Cell_170_249 |
PubMedID: 28669536 |
Gene_locus related to this paper: myctu-PKS13 |
Title : Screening a library of 1600 adamantyl ureas for anti-Mycobacterium tuberculosis activity in vitro and for better physical chemical properties for bioavailability - Scherman_2012_Bioorg.Med.Chem_20_3255 |
Author(s) : Scherman MS , North EJ , Jones V , Hess TN , Grzegorzewicz AE , Kasagami T , Kim IH , Merzlikin O , Lenaerts AJ , Lee RE , Jackson M , Morisseau C , McNeil MR |
Ref : Bioorganic & Medicinal Chemistry , 20 :3255 , 2012 |
Abstract : |
PubMedSearch : Scherman_2012_Bioorg.Med.Chem_20_3255 |
PubMedID: 22522007 |
Title : Inhibition of mycolic acid transport across the Mycobacterium tuberculosis plasma membrane - Grzegorzewicz_2012_Nat.Chem.Biol_8_334 |
Author(s) : Grzegorzewicz AE , Pham H , Gundi VA , Scherman MS , North EJ , Hess T , Jones V , Gruppo V , Born SE , Kordulakova J , Chavadi SS , Morisseau C , Lenaerts AJ , Lee RE , McNeil MR , Jackson M |
Ref : Nat Chemical Biology , 8 :334 , 2012 |
Abstract : |
PubMedSearch : Grzegorzewicz_2012_Nat.Chem.Biol_8_334 |
PubMedID: 22344175 |