Title : Synthetic Sansanmycin Analogues as Potent Mycobacterium tuberculosis Translocase I Inhibitors - Tran_2021_J.Med.Chem_64_17326 |
Author(s) : Tran W , Kusay AS , Hawkins PME , Cheung CY , Nagalingam G , Pujari V , Ford DJ , Stoye A , Ochoa JL , Audette RE , Hortle E , Oehlers SH , Charman SA , Linington RG , Rubin EJ , Dowson CG , Roper DI , Crick DC , Balle T , Cook GM , Britton WJ , Payne RJ |
Ref : Journal of Medicinal Chemistry , 64 :17326 , 2021 |
Abstract : |
PubMedSearch : Tran_2021_J.Med.Chem_64_17326 |
PubMedID: 34845906 |
Title : An Antibacterial beta-Lactone Kills Mycobacterium tuberculosis by Disrupting Mycolic Acid Biosynthesis - Lehmann_2018_Angew.Chem.Int.Ed.Engl_57_348 |
Author(s) : Lehmann J , Cheng TY , Aggarwal A , Park AS , Zeiler E , Raju RM , Akopian T , Kandror O , Sacchettini JC , Moody DB , Rubin EJ , Sieber SA |
Ref : Angew Chem Int Ed Engl , 57 :348 , 2018 |
Abstract : |
PubMedSearch : Lehmann_2018_Angew.Chem.Int.Ed.Engl_57_348 |
PubMedID: 29067779 |
Title : Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13 - Aggarwal_2017_Cell_170_249 |
Author(s) : Aggarwal A , Parai MK , Shetty N , Wallis D , Woolhiser L , Hastings C , Dutta NK , Galaviz S , Dhakal RC , Shrestha R , Wakabayashi S , Walpole C , Matthews D , Floyd D , Scullion P , Riley J , Epemolu O , Norval S , Snavely T , Robertson GT , Rubin EJ , Ioerger TR , Sirgel FA , van der Merwe R , van Helden PD , Keller P , Bottger EC , Karakousis PC , Lenaerts AJ , Sacchettini JC |
Ref : Cell , 170 :249 , 2017 |
Abstract : |
PubMedSearch : Aggarwal_2017_Cell_170_249 |
PubMedID: 28669536 |
Gene_locus related to this paper: myctu-PKS13 |
Title : Mycobacterium tuberculosis Rv2224c modulates innate immune responses - Rengarajan_2008_Proc.Natl.Acad.Sci.U.S.A_105_264 |
Author(s) : Rengarajan J , Murphy E , Park A , Krone CL , Hett EC , Bloom BR , Glimcher LH , Rubin EJ |
Ref : Proc Natl Acad Sci U S A , 105 :264 , 2008 |
Abstract : |
PubMedSearch : Rengarajan_2008_Proc.Natl.Acad.Sci.U.S.A_105_264 |
PubMedID: 18172199 |
Gene_locus related to this paper: myctu-ym24 |