Letchworth SR

General

Full name : Letchworth Sharon R

First name : Sharon

Mail : Targacept Inc., 200 E 1st St 300, Winston-Salem, NC 27101-4165

Zip Code :

City :

Country : USA

Email : Sharon.Letchworth@targacept.com

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References (13)

Title : Alpha4beta2 nicotinic receptors play a role in the nAChR-mediated decline in L-dopa-induced dyskinesias in parkinsonian rats - Quik_2013_Neuropharmacol_71_191
Author(s) : Quik M , Campos C , Bordia T , Strachan JP , Zhang J , McIntosh JM , Letchworth SR , Jordan K
Ref : Neuropharmacology , 71 :191 , 2013
Abstract :
PubMedSearch : Quik_2013_Neuropharmacol_71_191
PubMedID: 23583932

Title : Neuronal nicotinic receptor agonists ameliorate spontaneous motor asymmetries and motor discoordination in a unilateral mouse model of Parkinson's disease - Kucinski_2013_Pharmacol.Biochem.Behav_111_1
Author(s) : Kucinski A , Wersinger S , Stachowiak EK , Corso TD , Parry MJ , Zhang J , Jordan K , Letchworth SR , Bencherif M , Stachowiak MK
Ref : Pharmacol Biochem Behav , 111 :1 , 2013
Abstract :
PubMedSearch : Kucinski_2013_Pharmacol.Biochem.Behav_111_1
PubMedID: 23872135

Title : Nicotinic Receptor Agonists Reduce L-DOPA-Induced Dyskinesias in a Monkey Model of Parkinson's Disease - Zhang_2013_J.Pharmacol.Exp.Ther_347_225
Author(s) : Zhang D , Mallela A , Sohn D , Carroll FI , Bencherif M , Letchworth SR , Quik M
Ref : Journal of Pharmacology & Experimental Therapeutics , 347 :225 , 2013
Abstract :
PubMedSearch : Zhang_2013_J.Pharmacol.Exp.Ther_347_225
PubMedID: 23902940

Title : Analgesic effects mediated by neuronal nicotinic acetylcholine receptor agonists: correlation with desensitization of alpha4beta2* receptors - Zhang_2012_Eur.J.Pharm.Sci_47_813
Author(s) : Zhang J , Xiao YD , Jordan KG , Hammond PS , Van Dyke KM , Mazurov AA , Speake JD , Lippiello PM , James JW , Letchworth SR , Bencherif M , Hauser TA
Ref : Eur J Pharm Sci , 47 :813 , 2012
Abstract :
PubMedSearch : Zhang_2012_Eur.J.Pharm.Sci_47_813
PubMedID: 23036283

Title : Comparison of acetylcholine receptor interactions of the marine toxins, 13-desmethylspirolide C and gymnodimine - Hauser_2012_Neuropharmacol_62_2239
Author(s) : Hauser TA , Hepler CD , Kombo DC , Grinevich VP , Kiser MN , Hooker DN , Zhang J , Mountfort D , Selwood A , Akireddy SR , Letchworth SR , Yohannes D
Ref : Neuropharmacology , 62 :2239 , 2012
Abstract :
PubMedSearch : Hauser_2012_Neuropharmacol_62_2239
PubMedID: 22306792

Title : Poster: Construction of cell line heterologously expressing the alpha6\/3\/beta2\/beta3 nicotinic acetylcholine receptor (nAChR) subtype -
Author(s) : Whiteaker P , Lucero L , Lukas RJ , Hepler C , Strachan JP , Letchworth SR
Ref : Biochemical Pharmacology , 82 :1024 , 2011
PubMedID:

Title : Progress and challenges in the study of alpha6-containing nicotinic acetylcholine receptors - Letchworth_2011_Biochem.Pharmacol_82(8)_862
Author(s) : Letchworth SR , Whiteaker P
Ref : Biochemical Pharmacology , 82 :862 , 2011
Abstract :
PubMedSearch : Letchworth_2011_Biochem.Pharmacol_82(8)_862
PubMedID: 21736871

Title : Ispronicline: a novel alpha4beta2 nicotinic acetylcholine receptor-selective agonist with cognition-enhancing and neuroprotective properties - Lippiello_2006_J.Mol.Neurosci_30_19
Author(s) : Lippiello P , Letchworth SR , Gatto GJ , Traina VM , Bencherif M
Ref : Journal of Molecular Neuroscience , 30 :19 , 2006
Abstract :
PubMedSearch : Lippiello_2006_J.Mol.Neurosci_30_19
PubMedID: 17192610

Title : Long-lasting cognitive improvement with nicotinic receptor agonists: mechanisms of pharmacokinetic-pharmacodynamic discordance - Buccafusco_2005_Trends.Pharmacol.Sci_26_352
Author(s) : Buccafusco JJ , Letchworth SR , Bencherif M , Lippiello PM
Ref : Trends in Pharmacological Sciences , 26 :352 , 2005
Abstract :
PubMedSearch : Buccafusco_2005_Trends.Pharmacol.Sci_26_352
PubMedID: 15946748

Title : Heterologous expression of human {alpha}6{beta}4{beta}3{alpha}5 nicotinic acetylcholine receptors: binding properties consistent with their natural expression require quaternary subunit assembly including the {alpha}5 subunit - Grinevich_2005_J.Pharmacol.Exp.Ther_312_619
Author(s) : Grinevich VP , Letchworth SR , Lindenberger KA , Menager J , Mary V , Sadieva KA , Buhlman LM , Bohme GA , Pradier L , Benavides J , Lukas RJ , Bencherif M
Ref : Journal of Pharmacology & Experimental Therapeutics , 312 :619 , 2005
Abstract :
PubMedSearch : Grinevich_2005_J.Pharmacol.Exp.Ther_312_619
PubMedID: 15356217

Title : TC-1734: an orally active neuronal nicotinic acetylcholine receptor modulator with antidepressant, neuroprotective and long-lasting cognitive effects - Gatto_2004_CNS.Drug.Rev_10_147
Author(s) : Gatto GJ , Bohme GA , Caldwell WS , Letchworth SR , Traina VM , Obinu MC , Laville M , Reibaud M , Pradier L , Dunbar GC , Bencherif M
Ref : CNS Drug Rev , 10 :147 , 2004
Abstract :
PubMedSearch : Gatto_2004_CNS.Drug.Rev_10_147
PubMedID: 15179444

Title : Synthesis of a [2-pyridinyl-18F]-labelled fluoro derivative of (-)-cytisine as a candidate radioligand for brain nicotinic alpha4beta2 receptor imaging with PET - Roger_2003_Bioorg.Med.Chem_11_5333
Author(s) : Roger G , Lagnel B , Rouden J , Besret L , Valette H , Demphel S , Gopisetti J , Coulon C , Ottaviani M , Wrenn LA , Letchworth SR , Bohme GA , Benavides J , Lasne MC , Bottlaender M , Dolle F
Ref : Bioorganic & Medicinal Chemistry , 11 :5333 , 2003
Abstract :
PubMedSearch : Roger_2003_Bioorg.Med.Chem_11_5333
PubMedID: 14642577

Title : Functional and anatomical localization of mu opioid receptors in the striatum, amygdala, and extended amygdala of the nonhuman primate - Daunais_2001_J.Comp.Neurol_433_471
Author(s) : Daunais JB , Letchworth SR , Sim-Selley LJ , Smith HR , Childers SR , Porrino LJ
Ref : Journal of Comparative Neurology , 433 :471 , 2001
Abstract :
PubMedSearch : Daunais_2001_J.Comp.Neurol_433_471
PubMedID: 11304712