| Title : Butyrylcholinesterase-knockout reduces fibrillar beta-amyloid and conserves (18)FDG retention in 5XFAD mouse model of Alzheimer's disease - DeBay_2017_Brain.Res_1671_102 |
| Author(s) : DeBay DR , Reid GA , Macdonald IR , Mawko G , Burrell S , Martin E , Bowen CV , Darvesh S |
| Ref : Brain Research , 1671 :102 , 2017 |
| Abstract : |
| PubMedSearch : DeBay_2017_Brain.Res_1671_102 |
| PubMedID: 28729192 |
| Title : Targeting butyrylcholinesterase for preclinical single photon emission computed tomography (SPECT) imaging of Alzheimer's disease - DeBay_2017_Alzheimers.Dement.(N.Y)_3_166 |
| Author(s) : DeBay DR , Reid GA , Pottie IR , Martin E , Bowen CV , Darvesh S |
| Ref : Alzheimers Dement (N Y) , 3 :166 , 2017 |
| Abstract : |
| PubMedSearch : DeBay_2017_Alzheimers.Dement.(N.Y)_3_166 |
| PubMedID: 29067326 |
| Title : Synthesis and Preliminary Evaluation of Phenyl 4-123I-Iodophenylcarbamate for Visualization of Cholinesterases Associated with Alzheimer Disease Pathology - Macdonald_2016_J.Nucl.Med_57_297 |
| Author(s) : Macdonald IR , Reid GA , Pottie IR , Martin E , Darvesh S |
| Ref : J Nucl Med , 57 :297 , 2016 |
| Abstract : |
| PubMedSearch : Macdonald_2016_J.Nucl.Med_57_297 |
| PubMedID: 26541777 |
| Title : Development of acetophenone ligands as potential neuroimaging agents for cholinesterases - Jollymore-Hughes_2016_Bioorg.Med.Chem_24_5270 |
| Author(s) : Jollymore-Hughes CT , Pottie IR , Martin E , Rosenberry TL , Darvesh S |
| Ref : Bioorganic & Medicinal Chemistry , 24 :5270 , 2016 |
| Abstract : |
| PubMedSearch : Jollymore-Hughes_2016_Bioorg.Med.Chem_24_5270 |
| PubMedID: 27637382 |
| Title : Cholinesterase inhibition in Alzheimer's disease: is specificity the answer? - Macdonald_2014_J.Alzheimers.Dis_42_379 |
| Author(s) : Macdonald IR , Rockwood K , Martin E , Darvesh S |
| Ref : J Alzheimers Dis , 42 :379 , 2014 |
| Abstract : |
| PubMedSearch : Macdonald_2014_J.Alzheimers.Dis_42_379 |
| PubMedID: 24898642 |
| Title : Selectivity of phenothiazine cholinesterase inhibitors for neurotransmitter systems - Darvesh_2013_Bioorg.Med.Chem.Lett_23_3822 |
| Author(s) : Darvesh S , Macdonald IR , Martin E |
| Ref : Bioorganic & Medicinal Chemistry Lett , 23 :3822 , 2013 |
| Abstract : |
| PubMedSearch : Darvesh_2013_Bioorg.Med.Chem.Lett_23_3822 |
| PubMedID: 23707254 |
| Title : Thioesters for the in vitro evaluation of agents to image brain cholinesterases - Macdonald_2013_J.Enzyme.Inhib.Med.Chem_28_447 |
| Author(s) : Macdonald IR , Jollymore CT , Reid GA , Pottie IR , Martin E , Darvesh S |
| Ref : J Enzyme Inhib Med Chem , 28 :447 , 2013 |
| Abstract : |
| PubMedSearch : Macdonald_2013_J.Enzyme.Inhib.Med.Chem_28_447 |
| PubMedID: 22233541 |
| Title : Butyrylcholinesterase is associated with beta-amyloid plaques in the transgenic APPSWE\/PSEN1dE9 mouse model of Alzheimer disease - Darvesh_2012_J.Neuropathol.Exp.Neurol_71_2 |
| Author(s) : Darvesh S , Cash MK , Reid GA , Martin E , Mitnitski A , Geula C |
| Ref : J Neuropathol Experimental Neurology , 71 :2 , 2012 |
| Abstract : |
| PubMedSearch : Darvesh_2012_J.Neuropathol.Exp.Neurol_71_2 |
| PubMedID: 22157615 |
| Title : Probing the peripheral site of human butyrylcholinesterase - Macdonald_2012_Biochemistry_51_7046 |
| Author(s) : Macdonald IR , Martin E , Rosenberry TL , Darvesh S |
| Ref : Biochemistry , 51 :7046 , 2012 |
| Abstract : |
| PubMedSearch : Macdonald_2012_Biochemistry_51_7046 |
| PubMedID: 22901043 |
| Title : Synthesis and preliminary evaluation of piperidinyl and pyrrolidinyl iodobenzoates as imaging agents for butyrylcholinesterase - Macdonald_2011_Mol.Imaging.Biol_13_1250 |
| Author(s) : Macdonald IR , Reid GA , Joy EE , Pottie IR , Matte G , Burrell S , Mawko G , Martin E , Darvesh S |
| Ref : Mol Imaging Biol , 13 :1250 , 2011 |
| Abstract : |
| PubMedSearch : Macdonald_2011_Mol.Imaging.Biol_13_1250 |
| PubMedID: 20976626 |
| Title : Potentially procholinergic effects of medications commonly used in older adults - Rockwood_2011_Am.J.Geriatr.Pharmacother_9_80 |
| Author(s) : Rockwood K , Walsh R , Martin E , Darvesh S |
| Ref : Am J Geriatr Pharmacother , 9 :80 , 2011 |
| Abstract : |
| PubMedSearch : Rockwood_2011_Am.J.Geriatr.Pharmacother_9_80 |
| PubMedID: 21459311 |
| Title : Synergistic inhibition of butyrylcholinesterase by galantamine and citalopram - Walsh_2011_Biochim.Biophys.Acta_1810_1230 |
| Author(s) : Walsh R , Rockwood K , Martin E , Darvesh S |
| Ref : Biochimica & Biophysica Acta , 1810 :1230 , 2011 |
| Abstract : |
| PubMedSearch : Walsh_2011_Biochim.Biophys.Acta_1810_1230 |
| PubMedID: 21872646 |
| Title : Biochemical and histochemical comparison of cholinesterases in normal and Alzheimer brain tissues - Darvesh_2010_Curr.Alzheimer.Res_7_386 |
| Author(s) : Darvesh S , Reid GA , Martin E |
| Ref : Curr Alzheimer Res , 7 :386 , 2010 |
| Abstract : |
| PubMedSearch : Darvesh_2010_Curr.Alzheimer.Res_7_386 |
| PubMedID: 19939227 |
| Title : Differential binding of phenothiazine urea derivatives to wild-type human cholinesterases and butyrylcholinesterase mutants - Darvesh_2010_Bioorg.Med.Chem_18_2232 |
| Author(s) : Darvesh S , Pottie IR , Darvesh KV , McDonald RS , Walsh R , Conrad S , Penwell A , Mataija D , Martin E |
| Ref : Bioorganic & Medicinal Chemistry , 18 :2232 , 2010 |
| Abstract : |
| PubMedSearch : Darvesh_2010_Bioorg.Med.Chem_18_2232 |
| PubMedID: 20181484 |
| Title : Effects of physostigmine on microcirculatory alterations during experimental endotoxemia - Peter_2010_Shock_33_405 |
| Author(s) : Peter C , Schmidt K , Hofer S , Stephan M , Martin E , Weigand MA , Walther A |
| Ref : Shock , 33 :405 , 2010 |
| Abstract : |
| PubMedSearch : Peter_2010_Shock_33_405 |
| PubMedID: 20407407 |
| Title : Carbamates with differential mechanism of inhibition toward acetylcholinesterase and butyrylcholinesterase - Darvesh_2008_J.Med.Chem_51_4200 |
| Author(s) : Darvesh S , Darvesh KV , McDonald RS , Mataija D , Walsh R , Mothana S , Lockridge O , Martin E |
| Ref : Journal of Medicinal Chemistry , 51 :4200 , 2008 |
| Abstract : |
| PubMedSearch : Darvesh_2008_J.Med.Chem_51_4200 |
| PubMedID: 18570368 |
| Title : Pharmacologic cholinesterase inhibition improves survival in experimental sepsis - Hofer_2008_Crit.Care.Med_36_404 |
| Author(s) : Hofer S , Eisenbach C , Lukic IK , Schneider L , Bode K , Brueckmann M , Mautner S , Wente MN , Encke J , Werner J , Dalpke AH , Stremmel W , Nawroth PP , Martin E , Krammer PH , Bierhaus A , Weigand MA |
| Ref : Critical Care Medicine , 36 :404 , 2008 |
| Abstract : |
| PubMedSearch : Hofer_2008_Crit.Care.Med_36_404 |
| PubMedID: 18091537 |
| Title : Selective reversible inhibition of human butyrylcholinesterase by aryl amide derivatives of phenothiazine - Darvesh_2007_Bioorg.Med.Chem_15_6367 |
| Author(s) : Darvesh S , McDonald RS , Darvesh KV , Mataija D , Conrad S , Gomez G , Walsh R , Martin E |
| Ref : Bioorganic & Medicinal Chemistry , 15 :6367 , 2007 |
| Abstract : |
| PubMedSearch : Darvesh_2007_Bioorg.Med.Chem_15_6367 |
| PubMedID: 17681768 |
| Title : Homocysteine thiolactone and human cholinesterases - Darvesh_2007_Cell.Mol.Neurobiol_27_33 |
| Author(s) : Darvesh S , Walsh R , Martin E |
| Ref : Cellular Molecular Neurobiology , 27 :33 , 2007 |
| Abstract : |
| PubMedSearch : Darvesh_2007_Cell.Mol.Neurobiol_27_33 |
| PubMedID: 16955366 |
| Title : A versatile equation to describe reversible enzyme inhibition and activation kinetics: modeling beta-galactosidase and butyrylcholinesterase - Walsh_2007_Biochim.Biophys.Acta_1770_733 |
| Author(s) : Walsh R , Martin E , Darvesh S |
| Ref : Biochimica & Biophysica Acta , 1770 :733 , 2007 |
| Abstract : |
| PubMedSearch : Walsh_2007_Biochim.Biophys.Acta_1770_733 |
| PubMedID: 17307293 |
| Title : On the active site for hydrolysis of aryl amides and choline esters by human cholinesterases - Darvesh_2006_Bioorg.Med.Chem_14_4586 |
| Author(s) : Darvesh S , McDonald RS , Darvesh KV , Mataija D , Mothana S , Cook H , Carneiro KM , Richard N , Walsh R , Martin E |
| Ref : Bioorganic & Medicinal Chemistry , 14 :4586 , 2006 |
| Abstract : |
| PubMedSearch : Darvesh_2006_Bioorg.Med.Chem_14_4586 |
| PubMedID: 16504521 |
| Title : Structure-activity relationships for inhibition of human cholinesterases by alkyl amide phenothiazine derivatives - Darvesh_2005_Bioorg.Med.Chem_13_211 |
| Author(s) : Darvesh S , McDonald RS , Penwell A , Conrad S , Darvesh KV , Mataija D , Gomez G , Caines A , Walsh R , Martin E |
| Ref : Bioorganic & Medicinal Chemistry , 13 :211 , 2005 |
| Abstract : |
| PubMedSearch : Darvesh_2005_Bioorg.Med.Chem_13_211 |
| PubMedID: 15582466 |
| Title : Cholinesterase inhibitors modify the activity of intrinsic cardiac neurons - Darvesh_2004_Exp.Neurol_188_461 |
| Author(s) : Darvesh S , Arora RC , Martin E , Magee D , Hopkins DA , Armour JA |
| Ref : Experimental Neurology , 188 :461 , 2004 |
| Abstract : |
| PubMedSearch : Darvesh_2004_Exp.Neurol_188_461 |
| PubMedID: 15246845 |
| Title : Differential effects of lipid-lowering agents on human cholinesterases - Darvesh_2004_Clin.Biochem_37_42 |
| Author(s) : Darvesh S , Martin E , Walsh R , Rockwood K |
| Ref : Clinical Biochemistry , 37 :42 , 2004 |
| Abstract : |
| PubMedSearch : Darvesh_2004_Clin.Biochem_37_42 |
| PubMedID: 14675561 |
| Title : The stn-1 syntrophin gene of C.elegans is functionally related to dystrophin and dystrobrevin - Grisoni_2003_J.Mol.Biol_332_1037 |
| Author(s) : Grisoni K , Gieseler K , Mariol MC , Martin E , Carre-Pierrat M , Moulder G , Barstead R , Segalat L |
| Ref : Journal of Molecular Biology , 332 :1037 , 2003 |
| Abstract : |
| PubMedSearch : Grisoni_2003_J.Mol.Biol_332_1037 |
| PubMedID: 14499607 |
| Title : Inhibition of human cholinesterases by drugs used to treat Alzheimer disease - Darvesh_2003_Alzheimer.Dis.Assoc.Disord_17_117 |
| Author(s) : Darvesh S , Walsh R , Kumar R , Caines A , Roberts S , Magee D , Rockwood K , Martin E |
| Ref : Alzheimer Disease & Associated Disorders , 17 :117 , 2003 |
| Abstract : |
| PubMedSearch : Darvesh_2003_Alzheimer.Dis.Assoc.Disord_17_117 |
| PubMedID: 12794390 |
| Title : Enantiomer effects of huperzine A on the aryl acylamidase activity of human cholinesterases - Darvesh_2003_Cell.Mol.Neurobiol_23_93 |
| Author(s) : Darvesh S , Walsh R , Martin E |
| Ref : Cellular Molecular Neurobiology , 23 :93 , 2003 |
| Abstract : |
| PubMedSearch : Darvesh_2003_Cell.Mol.Neurobiol_23_93 |
| PubMedID: 12701885 |
| Title : Butyrylcholinesterase-Mediated enhancement of the enzymatic activity of trypsin - Darvesh_2001_Cell.Mol.Neurobiol_21_285 |
| Author(s) : Darvesh S , Kumar R , Roberts S , Walsh R , Martin E |
| Ref : Cellular Molecular Neurobiology , 21 :285 , 2001 |
| Abstract : |
| PubMedSearch : Darvesh_2001_Cell.Mol.Neurobiol_21_285 |
| PubMedID: 11569538 |
| Title : Cholinesterases in cardiac ganglia and modulation of canine intrinsic cardiac neuronal activity - Darvesh_1998_J.Auton.Nerv.Syst_71_75 |
| Author(s) : Darvesh S , MacDonald SE , Losier AM , Martin E , Hopkins DA , Armour JA |
| Ref : J Auton Nerv Syst , 71 :75 , 1998 |
| Abstract : |
| PubMedSearch : Darvesh_1998_J.Auton.Nerv.Syst_71_75 |
| PubMedID: 9760044 |
| Title : Dose-response, time-course of action and recovery of rocuronium bromide in children during halothane anaesthesia - Motsch_1995_Eur.J.Anaesthesiol.Supp_11_73 |
| Author(s) : Motsch J , Leuwer M , Bottiger BW , Bach A , Schonstedt R , Martin E |
| Ref : European Journal of Anaesthesiology Supplement , 11 :73 , 1995 |
| Abstract : |
| PubMedSearch : Motsch_1995_Eur.J.Anaesthesiol.Supp_11_73 |
| PubMedID: 8557011 |