| Title : Prolyl oligopeptidase inhibition reduces PolyQ aggregation and improves cell viability in cellular model of Huntington's disease - |
| Author(s) : Norrbacka S , Lindholm D , Myohanen TT |
| Ref : J Cell Mol Med , 23 :8511 , 2019 |
| PubMedID: 31565846 |
| Title : New tricks of prolyl oligopeptidase inhibitors - A common drug therapy for several neurodegenerative diseases - Svarcbahs_2019_Biochem.Pharmacol_161_113 |
| Author(s) : Svarcbahs R , Julku U , Kilpelainen T , Kyyro M , Jantti M , Myohanen TT |
| Ref : Biochemical Pharmacology , 161 :113 , 2019 |
| Abstract : |
| PubMedSearch : Svarcbahs_2019_Biochem.Pharmacol_161_113 |
| PubMedID: 30660495 |
| Title : Prolyl Oligopeptidase Regulates Dopamine Transporter Phosphorylation in the Nigrostriatal Pathway of Mouse - Julku_2018_Mol.Neurobiol_55_470 |
| Author(s) : Julku UH , Panhelainen AE , Tiilikainen SE , Svarcbahs R , Tammimaki AE , Piepponen TP , Savolainen MH , Myohanen TT |
| Ref : Molecular Neurobiology , 55 :470 , 2018 |
| Abstract : |
| PubMedSearch : Julku_2018_Mol.Neurobiol_55_470 |
| PubMedID: 27966077 |
| Title : Prolyl oligopeptidase inhibition attenuates the toxicity of a proteasomal inhibitor, lactacystin, in the alpha-synuclein overexpressing cell culture - Myohanen_2017_Neurosci.Lett_636_83 |
| Author(s) : Myohanen TT , Norrbacka S , Savolainen MH |
| Ref : Neuroscience Letters , 636 :83 , 2017 |
| Abstract : |
| PubMedSearch : Myohanen_2017_Neurosci.Lett_636_83 |
| PubMedID: 27818354 |
| Title : Prolyl Oligopeptidase Enhances alpha-Synuclein Dimerization via Direct Protein-Protein Interaction - Savolainen_2015_J.Biol.Chem_290_5117 |
| Author(s) : Savolainen MH , Yan X , Myohanen TT , Huttunen HJ |
| Ref : Journal of Biological Chemistry , 290 :5117 , 2015 |
| Abstract : |
| PubMedSearch : Savolainen_2015_J.Biol.Chem_290_5117 |
| PubMedID: 25555914 |
| Gene_locus related to this paper: human-PREP |
| Title : The beneficial effect of a prolyl oligopeptidase inhibitor, KYP-2047, on alpha-synuclein clearance and autophagy in A30P transgenic mouse - Savolainen_2014_Neurobiol.Dis_68_1 |
| Author(s) : Savolainen MH , Richie CT , Harvey BK , Mannisto PT , Maguire-Zeiss KA , Myohanen TT |
| Ref : Neurobiol Dis , 68 :1 , 2014 |
| Abstract : |
| PubMedSearch : Savolainen_2014_Neurobiol.Dis_68_1 |
| PubMedID: 24746855 |
| Title : Inhibition of prolyl oligopeptidase increases the survival of alpha-synuclein overexpressing cells after rotenone exposure by reducing alpha-synuclein oligomers - Dokleja_2014_Neurosci.Lett_583_37 |
| Author(s) : Dokleja L , Hannula MJ , Myohanen TT |
| Ref : Neuroscience Letters , 583 :37 , 2014 |
| Abstract : |
| PubMedSearch : Dokleja_2014_Neurosci.Lett_583_37 |
| PubMedID: 25240592 |
| Title : Distribution of prolyl oligopeptidase in human peripheral tissues and in ovarian and colorectal tumors - Myohanen_2012_J.Histochem.Cytochem_60_706 |
| Author(s) : Myohanen TT , Pyykko E , Mannisto PT , Carpen O |
| Ref : Journal of Histochemistry & Cytochemistry , 60 :706 , 2012 |
| Abstract : |
| PubMedSearch : Myohanen_2012_J.Histochem.Cytochem_60_706 |
| PubMedID: 22740343 |
| Title : A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease - Myohanen_2012_Br.J.Pharmacol_166_1097 |
| Author(s) : Myohanen TT , Hannula MJ , Van Elzen R , Gerard M , Van der Veken P , Garcia-Horsman JA , Baekelandt V , Mannisto PT , Lambeir AM |
| Ref : British Journal of Pharmacology , 166 :1097 , 2012 |
| Abstract : |
| PubMedSearch : Myohanen_2012_Br.J.Pharmacol_166_1097 |
| PubMedID: 22233220 |
| Title : Association of prolyl oligopeptidase with conventional neurotransmitters in the brain - Peltonen_2011_CNS.Neurol.Disord.Drug.Targets_10_311 |
| Author(s) : Peltonen I , Myohanen TT , Mannisto PT |
| Ref : CNS Neurol Disord Drug Targets , 10 :311 , 2011 |
| Abstract : |
| PubMedSearch : Peltonen_2011_CNS.Neurol.Disord.Drug.Targets_10_311 |
| PubMedID: 21222629 |
| Title : Prolyl oligopeptidase induces angiogenesis both in vitro and in vivo in a novel regulatory manner - Myohanen_2011_Br.J.Pharmacol_163_1666 |
| Author(s) : Myohanen TT , Tenorio-Laranga J , Jokinen B , Vazquez-Sanchez R , Moreno-Baylach MJ , Garcia-Horsman JA , Mannisto PT |
| Ref : British Journal of Pharmacology , 163 :1666 , 2011 |
| Abstract : |
| PubMedSearch : Myohanen_2011_Br.J.Pharmacol_163_1666 |
| PubMedID: 21133893 |