Title : A prolyl oligopeptidase inhibitor, KYP-2047, reduces alpha-synuclein protein levels and aggregates in cellular and animal models of Parkinson's disease - Myohanen_2012_Br.J.Pharmacol_166_1097 |
Author(s) : Myohanen TT , Hannula MJ , Van Elzen R , Gerard M , Van der Veken P , Garcia-Horsman JA , Baekelandt V , Mannisto PT , Lambeir AM |
Ref : British Journal of Pharmacology , 166 :1097 , 2012 |
Abstract : |
PubMedSearch : Myohanen_2012_Br.J.Pharmacol_166_1097 |
PubMedID: 22233220 |
Title : P2-substituted N-acylprolylpyrrolidine inhibitors of prolyl oligopeptidase: biochemical evaluation, binding mode determination, and assessment in a cellular model of synucleinopathy - Van der Veken_2012_J.Med.Chem_55_9856 |
Author(s) : Van der Veken P , Fulop V , Rea D , Gerard M , Van Elzen R , Joossens J , Cheng JD , Baekelandt V , De Meester I , Lambeir AM , Augustyns K |
Ref : Journal of Medicinal Chemistry , 55 :9856 , 2012 |
Abstract : |
PubMedSearch : Van der Veken_2012_J.Med.Chem_55_9856 |
PubMedID: 23121075 |
Gene_locus related to this paper: pig-ppce |
Title : Prolyl oligopeptidase stimulates the aggregation of alpha-synuclein - Brandt_2008_Peptides_29_1472 |
Author(s) : Brandt I , Gerard M , Sergeant K , Devreese B , Baekelandt V , Augustyns K , Scharpe S , Engelborghs Y , Lambeir AM |
Ref : Peptides , 29 :1472 , 2008 |
Abstract : |
PubMedSearch : Brandt_2008_Peptides_29_1472 |
PubMedID: 18571285 |