| Title : Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors - Butini_2008_J.Med.Chem_51_3154 |
| Author(s) : Butini S , Campiani G , Borriello M , Gemma S , Panico A , Persico M , Catalanotti B , Ros S , Brindisi M , Agnusdei M , Fiorini I , Nacci V , Novellino E , Belinskaya T , Saxena A , Fattorusso C |
| Ref : Journal of Medicinal Chemistry , 51 :3154 , 2008 |
| Abstract : |
| PubMedSearch : Butini_2008_J.Med.Chem_51_3154 |
| PubMedID: 18479118 |
| Title : Discovery of huperzine A-tacrine hybrids as potent inhibitors of human cholinesterases targeting their midgorge recognition sites - Gemma_2006_J.Med.Chem_49_3421 |
| Author(s) : Gemma S , Gabellieri E , Huleatt P , Fattorusso C , Borriello M , Catalanotti B , Butini S , De Angelis M , Novellino E , Nacci V , Belinskaya T , Saxena A , Campiani G |
| Ref : Journal of Medicinal Chemistry , 49 :3421 , 2006 |
| Abstract : |
| PubMedSearch : Gemma_2006_J.Med.Chem_49_3421 |
| PubMedID: 16722663 |
| Title : Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors - Campiani_2005_J.Med.Chem_48_1919 |
| Author(s) : Campiani G , Fattorusso C , Butini S , Gaeta A , Agnusdei M , Gemma S , Persico M , Catalanotti B , Savini L , Nacci V , Novellino E , Holloway HW , Greig NH , Belinskaya T , Fedorko JM , Saxena A |
| Ref : Journal of Medicinal Chemistry , 48 :1919 , 2005 |
| Abstract : |
| PubMedSearch : Campiani_2005_J.Med.Chem_48_1919 |
| PubMedID: 15771436 |
| Title : Synthesis and anticholinesterase activity of huperzine A analogues containing phenol and catechol replacements for the pyridone ring - Campiani_1998_Bioorg.Med.Chem.Lett_8_1413 |
| Author(s) : Campiani G , Kozikowski AP , Wang S , Ming L , Nacci V , Saxena A , Doctor BP |
| Ref : Bioorganic & Medicinal Chemistry Lett , 8 :1413 , 1998 |
| Abstract : |
| PubMedSearch : Campiani_1998_Bioorg.Med.Chem.Lett_8_1413 |
| PubMedID: 9871776 |