Title : Multitarget drugs as potential therapeutic agents for alzheimer's disease. A new family of 5-substituted indazole derivatives as cholinergic and BACE1 inhibitors - Gonzalez-Naranjo_2022_J.Enzyme.Inhib.Med.Chem_37_2348 |
Author(s) : Gonzalez-Naranjo P , Perez C , Gonzalez-Sanchez M , Gironda-Martinez A , Ulzurrun E , Bartolome F , Rubio-Fernandez M , Martin-Requero A , Campillo NE , Paez JA |
Ref : J Enzyme Inhib Med Chem , 37 :2348 , 2022 |
Abstract : |
PubMedSearch : Gonzalez-Naranjo_2022_J.Enzyme.Inhib.Med.Chem_37_2348 |
PubMedID: 36050834 |
Title : Targeting Cannabinoid Receptor Activation and BACE-1 Activity Counteracts TgAPP Mice Memory Impairment and Alzheimer's Disease Lymphoblast Alterations - Nunez-Borque_2020_Mol.Neurobiol__ |
Author(s) : Nunez-Borque E , Gonzalez-Naranjo P , Bartolome F , Alquezar C , Reinares-Sebastian A , Perez C , Ceballos ML , Paez JA , Campillo NE , Martin-Requero A |
Ref : Molecular Neurobiology , : , 2020 |
Abstract : |
PubMedSearch : Nunez-Borque_2020_Mol.Neurobiol__ |
PubMedID: 31898159 |
Title : Indazolylketones as new multitarget cannabinoid drugs - Gonzalez-Naranjo_2019_Eur.J.Med.Chem_166_90 |
Author(s) : Gonzalez-Naranjo P , Perez-Macias N , Perez C , Roca C , Vaca G , Giron R , Sanchez-Robles E , Martin-Fontelles MI , de Ceballos ML , Martin-Requero A , Campillo NE , Paez JA |
Ref : Eur Journal of Medicinal Chemistry , 166 :90 , 2019 |
Abstract : |
PubMedSearch : Gonzalez-Naranjo_2019_Eur.J.Med.Chem_166_90 |
PubMedID: 30685536 |
Title : Activation of the Cannabinoid Type 2 Receptor by a Novel Indazole Derivative Normalizes the Survival Pattern of Lymphoblasts from Patients with Late-Onset Alzheimer's Disease - Del Cerro_2018_CNS.Drugs_32_579 |
Author(s) : Del Cerro P , Alquezar C , Bartolome F , Gonzalez-Naranjo P , Perez C , Carro E , Paez JA , Campillo NE , Martin-Requero A |
Ref : CNS Drugs , 32 :579 , 2018 |
Abstract : |
PubMedSearch : Del Cerro_2018_CNS.Drugs_32_579 |
PubMedID: 29736745 |
Title : Cannabinoid agonists showing BuChE inhibition as potential therapeutic agents for Alzheimer's disease - Gonzalez-Naranjo_2014_Eur.J.Med.Chem_73_56 |
Author(s) : Gonzalez-Naranjo P , Perez-Macias N , Campillo NE , Perez C , Aran VJ , Giron R , Sanchez-Robles E , Martin MI , Gomez-Canas M , Garcia-Arencibia M , Fernandez-Ruiz J , Paez JA |
Ref : Eur Journal of Medicinal Chemistry , 73 :56 , 2014 |
Abstract : |
PubMedSearch : Gonzalez-Naranjo_2014_Eur.J.Med.Chem_73_56 |
PubMedID: 24378710 |
Title : Multitarget cannabinoids as novel strategy for Alzheimer disease - Gonzalez-Naranjo_2013_Curr.Alzheimer.Res_10_229 |
Author(s) : Gonzalez-Naranjo P , Campillo NE , Perez C , Paez JA |
Ref : Curr Alzheimer Res , 10 :229 , 2013 |
Abstract : |
PubMedSearch : Gonzalez-Naranjo_2013_Curr.Alzheimer.Res_10_229 |
PubMedID: 23369066 |
Title : Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties - Fernandez-Bachiller_2009_ChemMedChem_4_828 |
Author(s) : Fernandez-Bachiller MI , Perez C , Campillo NE , Paez JA , Gonzalez-Munoz GC , Usan P , Garcia-Palomero E , Lopez MG , Villarroya M , Garcia AG , Martinez A , Rodriguez-Franco MI |
Ref : ChemMedChem , 4 :828 , 2009 |
Abstract : |
PubMedSearch : Fernandez-Bachiller_2009_ChemMedChem_4_828 |
PubMedID: 19308922 |