Garcia AG

References (31)

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Author(s) : de Diego AM , Lorrio S , Calvo-Gallardo E , Garcia AG
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PubMedSearch : de Diego_2012_Biochem.Biophys.Res.Commun_428_482
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Title : Effects of novel tacripyrines ITH12117 and ITH12118 on rat vas deferens contractions, calcium transients and cholinesterase activity - Pereira_2011_Eur.J.Pharmacol_660_411
Author(s) : Pereira JD , Caricati-Neto A , Miranda-Ferreira R , Smaili SS , Godinho RO , de los Rios C , Leon R , Villaroya M , Samadi A , Marco-Contelles J , Jurkiewicz NH , Garcia AG , Jurkiewicz A
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PubMedSearch : Pereira_2011_Eur.J.Pharmacol_660_411
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Title : N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease - Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224
Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Romero A , Del Barrio L , Martin-de-Saavedra MD , Egea J , Leon R , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI
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Title : Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties - Fernandez-Bachiller_2010_J.Med.Chem_53_4927
Author(s) : Fernandez-Bachiller MI , Perez C , Gonzalez-Munoz GC , Conde S , Lopez MG , Villarroya M , Garcia AG , Rodriguez-Franco MI
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Title : Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells - Romero_2010_J.Pineal.Res_49_141
Author(s) : Romero A , Egea J , Garcia AG , Lopez MG
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Title : Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases - Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152
Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI
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Title : Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles - Samadi_2010_Bioorg.Med.Chem_18_5861
Author(s) : Samadi A , Marco-Contelles J , Soriano E , Alvarez-Perez M , Chioua M , Romero A , Gonzalez-Lafuente L , Gandia L , Roda JM , Lopez MG , Villarroya M , Garcia AG , Rios Cde L
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Title : Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives - de Los Rios_2010_J.Med.Chem_53_5129
Author(s) : de los Rios C , Egea J , Marco-Contelles J , Leon R , Samadi A , Iriepa I , Moraleda I , Galvez E , Garcia AG , Lopez MG , Villarroya M , Romero A
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Title : Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils - Lorrio_2009_Brain.Res_1254_128
Author(s) : Lorrio S , Negredo P , Roda JM , Garcia AG , Lopez MG
Ref : Brain Research , 1254 :128 , 2009
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Title : Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease - Arce_2009_J.Med.Chem_52_7249
Author(s) : Arce MP , Rodriguez-Franco MI , Gonzalez-Munoz GC , Perez C , Lopez B , Villarroya M , Lopez MG , Garcia AG , Conde S
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Title : Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties - Fernandez-Bachiller_2009_ChemMedChem_4_828
Author(s) : Fernandez-Bachiller MI , Perez C , Campillo NE , Paez JA , Gonzalez-Munoz GC , Usan P , Garcia-Palomero E , Lopez MG , Villarroya M , Garcia AG , Martinez A , Rodriguez-Franco MI
Ref : ChemMedChem , 4 :828 , 2009
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PubMedSearch : Fernandez-Bachiller_2009_ChemMedChem_4_828
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Title : New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties - Leon_2008_Bioorg.Med.Chem_16_7759
Author(s) : Leon R , de los Rios C , Marco-Contelles J , Huertas O , Barril X , Luque FJ , Lopez MG , Garcia AG , Villarroya M
Ref : Bioorganic & Medicinal Chemistry , 16 :7759 , 2008
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PubMedSearch : Leon_2008_Bioorg.Med.Chem_16_7759
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Title : An update on the pharmacology of galantamine - Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987
Author(s) : Villarroya M , Garcia AG , Marco-Contelles J , Lopez MG
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PubMedSearch : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987
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Title : Desensitized nicotinic receptors that, however, afford cytoprotection in bovine chromaffin cells - Egea_2006_J.Mol.Neurosci_30_59
Author(s) : Egea J , Hernandez-Guijo JM , Olivares R , Lopez MG , Garcia AG
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Title : Can cholinesterase inhibitors provide additional effects to cholinergic neurotransmission enhancement? - Lopez_2006_J.Mol.Neurosci_30_141
Author(s) : Lopez MG , Arias E , Sobrado M , Lorrio S , Roda JM , Garcia AG
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Title : A comparison between acetylcholine-like action potentials and square depolarizing pulses in triggering calcium entry and exocytosis in bovine chromaffin cells - Garcia_2006_J.Mol.Neurosci_30_57
Author(s) : Garcia de Diego AM , Arnaiz JJ , Gandia L , Hernandez-Guijo JM , Garcia AG
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PubMedSearch : Garcia_2006_J.Mol.Neurosci_30_57
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Title : Neuroprotection by nicotine in hippocampal slices subjected to oxygen-glucose deprivation: involvement of the alpha7 nAChR subtype - Rosa_2006_J.Mol.Neurosci_30_61
Author(s) : Rosa AO , Egea J , Gandia L , Lopez MG , Garcia AG
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Title : Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease - Marco-Contelles_2006_J.Med.Chem_49_7607
Author(s) : Marco-Contelles J , Leon R , de los Rios C , Guglietta A , Terencio J , Lopez MG , Garcia AG , Villarroya M
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PubMedSearch : Marco-Contelles_2006_J.Med.Chem_49_7607
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Title : Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals - Marco-Contelles_2006_Eur.J.Med.Chem_41_1464
Author(s) : Marco-Contelles J , Leon R , Lopez MG , Garcia AG , Villarroya M
Ref : Eur Journal of Medicinal Chemistry , 41 :1464 , 2006
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Title : Blockade of Ca2+ -activated K+ channels by galantamine can also contribute to the potentiation of catecholamine secretion from chromaffin cells - Ales_2006_Eur.J.Pharmacol_548_45
Author(s) : Ales E , Gullo F , Arias E , Olivares R , Garcia AG , Wanke E , Lopez MG
Ref : European Journal of Pharmacology , 548 :45 , 2006
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PubMedSearch : Ales_2006_Eur.J.Pharmacol_548_45
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Title : Enhancement of secretion by threshold nicotinic stimulation in bovine chromaffin cells - Tapia_2006_J.Mol.Neurosci_30_81
Author(s) : Tapia L , Eguiagaray JG , Egea J , Garcia AG , Gandia L
Ref : Journal of Molecular Neuroscience , 30 :81 , 2006
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PubMedSearch : Tapia_2006_J.Mol.Neurosci_30_81
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Title : Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors - Arias_2005_J.Pharmacol.Exp.Ther_315_1346
Author(s) : Arias E , Gallego-Sandin S , Villarroya M , Garcia AG , Lopez MG
Ref : Journal of Pharmacology & Experimental Therapeutics , 315 :1346 , 2005
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PubMedSearch : Arias_2005_J.Pharmacol.Exp.Ther_315_1346
PubMedID: 16144975

Title : Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues - Leon_2005_Bioorg.Med.Chem_13_1167
Author(s) : Leon R , Marco-Contelles J , Garcia AG , Villarroya M
Ref : Bioorganic & Medicinal Chemistry , 13 :1167 , 2005
Abstract :
PubMedSearch : Leon_2005_Bioorg.Med.Chem_13_1167
PubMedID: 15670925

Title : Synthesis, biological evaluation and molecular modelling of diversely functionalized heterocyclic derivatives as inhibitors of acetylcholinesterase\/butyrylcholinesterase and modulators of Ca2+ channels and nicotinic receptors - Marco_2004_Bioorg.Med.Chem_12_2199
Author(s) : Marco JL , de los Rios C , Garcia AG , Villarroya M , Carreiras MC , Martins C , Eleuterio A , Morreale A , Orozco M , Luque FJ
Ref : Bioorganic & Medicinal Chemistry , 12 :2199 , 2004
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PubMedSearch : Marco_2004_Bioorg.Med.Chem_12_2199
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Title : Enhancement of purinergic neurotransmission by galantamine and other acetylcholinesterase inhibitors in the rat vas deferens - Caricati-Neto_2004_Eur.J.Pharmacol_503_191
Author(s) : Caricati-Neto A , D'Angelo L C , Reuter H , Hyppolito Jurkiewicz N , Garcia AG , Jurkiewicz A
Ref : European Journal of Pharmacology , 503 :191 , 2004
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PubMedSearch : Caricati-Neto_2004_Eur.J.Pharmacol_503_191
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Title : Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation - Sobrado_2004_Neurosci.Lett_365_132
Author(s) : Sobrado M , Roda JM , Lopez MG , Egea J , Garcia AG
Ref : Neuroscience Letters , 365 :132 , 2004
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PubMedSearch : Sobrado_2004_Neurosci.Lett_365_132
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Title : Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors - Arias_2004_Neuropharmacol_46_103
Author(s) : Arias E , Ales E , Gabilan NH , Cano-Abad MF , Villarroya M , Garcia AG , Lopez MG
Ref : Neuropharmacology , 46 :103 , 2004
Abstract :
PubMedSearch : Arias_2004_Neuropharmacol_46_103
PubMedID: 14654102

Title : New classes of AChE inhibitors with additional pharmacological effects of interest for the treatment of Alzheimer's disease - Villarroya_2004_Curr.Pharm.Des_10_3177
Author(s) : Villarroya M , Garcia AG , Marco JL
Ref : Curr Pharm Des , 10 :3177 , 2004
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PubMedSearch : Villarroya_2004_Curr.Pharm.Des_10_3177
PubMedID: 15544507

Title : ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylat e), a novel acetylcholinesterase inhibitor with calcium promotor and neuroprotective properties - Orozco_2004_J.Pharmacol.Exp.Ther_310_987
Author(s) : Orozco C , de los Rios C , Arias E , Leon R , Garcia AG , Marco JL , Villarroya M , Lopez MG
Ref : Journal of Pharmacology & Experimental Therapeutics , 310 :987 , 2004
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PubMedSearch : Orozco_2004_J.Pharmacol.Exp.Ther_310_987
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Title : Novel tacrine derivatives that block neuronal calcium channels - de los Rios_2002_Bioorg.Med.Chem_10_2077
Author(s) : de los Rios C , Marco JL , Carreiras MD , Chinchon PM , Garcia AG , Villarroya M
Ref : Bioorganic & Medicinal Chemistry , 10 :2077 , 2002
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PubMedSearch : de los Rios_2002_Bioorg.Med.Chem_10_2077
PubMedID: 11937366

Title : [Treatment of mild cognitive impairment: value of citicoline] - Abad_2002_Rev.Neurol_35_675
Author(s) : Abad Santos F , Novalbos J , Gallego Sandin S , Garcia AG
Ref : Rev Neurol , 35 :675 , 2002
Abstract :
PubMedSearch : Abad_2002_Rev.Neurol_35_675
PubMedID: 12389156