Lopez MG

References (36)

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Author(s) : Michalska P , Mayo P , Fernandez-Mendivil C , Tenti G , Duarte P , Buendia I , Ramos MT , Lopez MG , Menendez JC , Leon R
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Abstract : Michalska_2020_Antioxidants.(Basel)_9_
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Title : Neuroprotective activity of isoquinoline alkaloids from of Chilean Amaryllidaceae plants against oxidative stress-induced cytotoxicity on human neuroblastoma SH-SY5Y cells and mouse hippocampal slice culture - Trujillo-Chacon_2019_Food.Chem.Toxicol_132_110665
Author(s) : Trujillo-Chacon LM , Alarcon-Enos JE , Cespedes-Acuna CL , Bustamante L , Baeza M , Lopez MG , Fernandez-Mendivil C , Cabezas F , Pastene-Navarrete ER
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Title : Enzymatic and solid-phase synthesis of new donepezil-based L- and d-glutamic acid derivatives and their pharmacological evaluation in models related to Alzheimer's disease and cerebral ischemia - Monjas_2017_Eur.J.Med.Chem_130_60
Author(s) : Monjas L , Arce MP , Leon R , Egea J , Perez C , Villarroya M , Lopez MG , Gil C , Conde S , Rodriguez-Franco MI
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Abstract : Monjas_2017_Eur.J.Med.Chem_130_60
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Title : Subthreshold Concentrations of Melatonin and Galantamine Improves Pathological AD-Hallmarks in Hippocampal Organotypic Cultures - Buendia_2016_Mol.Neurobiol_53_3338
Author(s) : Buendia I , Parada E , Navarro E , Leon R , Negredo P , Egea J , Lopez MG
Ref : Molecular Neurobiology , 53 :3338 , 2016
Abstract : Buendia_2016_Mol.Neurobiol_53_3338
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Title : Anti-inflammatory role of microglial alpha7 nAChRs and its role in neuroprotection - Egea_2015_Biochem.Pharmacol_97(4)_463
Author(s) : Egea J , Buendia I , Parada E , Navarro E , Leon R , Lopez MG
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Abstract : Egea_2015_Biochem.Pharmacol_97(4)_463
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Title : Alpha7 nicotinic receptor activation protects against oxidative stress via heme-oxygenase I induction - Navarro_2015_Biochem.Pharmacol_97(4)_473
Author(s) : Navarro E , Buendia I , Parada E , Leon R , Jansen-Duerr P , Pircher H , Egea J , Lopez MG
Ref : Biochemical Pharmacology , 97 :473 , 2015
Abstract : Navarro_2015_Biochem.Pharmacol_97(4)_473
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PubMedSearch : Navarro_2015_Biochem.Pharmacol_97(4)_473
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Title : Poster: Importance of microglial alpha7 nicotinic receptors in neuroprotection: The central cholinergic anti-inflammatory pathway -
Author(s) : Lopez MG , Parada E , Egea J
Ref : Biochemical Pharmacology , 97 :625 , 2015
PubMedID:

Title : Novel tacrine-grafted ugi adducts as multipotent anti-Alzheimer drugs: a synthetic renewal in tacrine-ferulic Acid hybrids - Benchekroun_2015_ChemMedChem_10_523
Author(s) : Benchekroun M , Bartolini M , Egea J , Romero A , Soriano E , Pudlo M , Luzet V , Andrisano V , Jimeno ML , Lopez MG , Wehle S , Gharbi T , Refouvelet B , de Andres L , Herrera-Arozamena C , Monti B , Bolognesi ML , Rodriguez-Franco MI , Decker M , Marco-Contelles J , Ismaili L
Ref : ChemMedChem , 10 :523 , 2015
Abstract : Benchekroun_2015_ChemMedChem_10_523
ESTHER : Benchekroun_2015_ChemMedChem_10_523
PubMedSearch : Benchekroun_2015_ChemMedChem_10_523
PubMedID: 25537267

Title : Chalcones as positive allosteric modulators of alpha7 nicotinic acetylcholine receptors: a new target for a privileged structure - Balsera_2014_Eur.J.Med.Chem_86_724
Author(s) : Balsera B , Mulet J , Fernandez-Carvajal A , de la Torre-Martinez R , Ferrer-Montiel A , Hernandez-Jimenez JG , Estevez-Herrera J , Borges R , Freitas AE , Lopez MG , Garcia-Lopez MT , Gonzalez-Muniz R , Perez de Vega MJ , Valor LM , Svobodova L , Sala S , Sala F , Criado M
Ref : Eur Journal of Medicinal Chemistry , 86 :724 , 2014
Abstract : Balsera_2014_Eur.J.Med.Chem_86_724
ESTHER : Balsera_2014_Eur.J.Med.Chem_86_724
PubMedSearch : Balsera_2014_Eur.J.Med.Chem_86_724
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Title : New melatonin-N,N-dibenzyl(N-methyl)amine hybrids: potent neurogenic agents with antioxidant, cholinergic, and neuroprotective properties as innovative drugs for Alzheimer's disease - Lopez-Iglesias_2014_J.Med.Chem_57_3773
Author(s) : Lopez-Iglesias B , Perez C , Morales-Garcia JA , Alonso-Gil S , Perez-Castillo A , Romero A , Lopez MG , Villarroya M , Conde S , Rodriguez-Franco MI
Ref : Journal of Medicinal Chemistry , 57 :3773 , 2014
Abstract : Lopez-Iglesias_2014_J.Med.Chem_57_3773
ESTHER : Lopez-Iglesias_2014_J.Med.Chem_57_3773
PubMedSearch : Lopez-Iglesias_2014_J.Med.Chem_57_3773
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Title : Isoxazolotacrines as non-toxic and selective butyrylcholinesterase inhibitors for Alzheimer's disease - Cherif_2014_Future.Med.Chem_6_1883
Author(s) : Cherif O , Allouche F , Chabchoub F , Chioua M , Soriano E , Yanez M , Cacabelos R , Romero A , Lopez MG , Marco-Contelles J
Ref : Future Med Chem , 6 :1883 , 2014
Abstract : Cherif_2014_Future.Med.Chem_6_1883
ESTHER : Cherif_2014_Future.Med.Chem_6_1883
PubMedSearch : Cherif_2014_Future.Med.Chem_6_1883
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Title : PP2A ligand ITH12246 protects against memory impairment and focal cerebral ischemia in mice - Lorrio_2013_ACS.Chem.Neurosci_4_1267
Author(s) : Lorrio S , Romero A , Gonzalez-Lafuente L , Lajarin-Cuesta R , Martinez-Sanz FJ , Estrada M , Samadi A , Marco-Contelles J , Rodriguez-Franco MI , Villarroya M , Lopez MG , de los Rios C
Ref : ACS Chem Neurosci , 4 :1267 , 2013
Abstract : Lorrio_2013_ACS.Chem.Neurosci_4_1267
ESTHER : Lorrio_2013_ACS.Chem.Neurosci_4_1267
PubMedSearch : Lorrio_2013_ACS.Chem.Neurosci_4_1267
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Title : N-acylaminophenothiazines: neuroprotective agents displaying multifunctional activities for a potential treatment of Alzheimer's disease - Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224
Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Romero A , Del Barrio L , Martin-de-Saavedra MD , Egea J , Leon R , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI
Ref : Eur Journal of Medicinal Chemistry , 46 :2224 , 2011
Abstract : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224
ESTHER : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224
PubMedSearch : Gonzalez-Munoz_2011_Eur.J.Med.Chem_46_2224
PubMedID: 21420206

Title : Neurotoxicity induced by okadaic acid in the human neuroblastoma SH-SY5Y line can be differentially prevented by alpha7 and beta2* nicotinic stimulation - Del Barrio_2011_Toxicol.Sci_123_193
Author(s) : Del Barrio L , Martin-de-Saavedra MD , Romero A , Parada E , Egea J , Avila J , McIntosh JM , Wonnacott S , Lopez MG
Ref : Toxicol Sci , 123 :193 , 2011
Abstract : Del Barrio_2011_Toxicol.Sci_123_193
ESTHER : Del Barrio_2011_Toxicol.Sci_123_193
PubMedSearch : Del Barrio_2011_Toxicol.Sci_123_193
PubMedID: 21715663

Title : Synthesis and pharmacological assessment of diversely substituted pyrazolo[3,4-b]quinoline, and benzo[b]pyrazolo[4,3-g][1,8]naphthyridine derivatives - Silva_2011_Eur.J.Med.Chem_46_4676
Author(s) : Silva D , Chioua M , Samadi A , Carmo Carreiras M , Jimeno ML , Mendes E , Rios Cde L , Romero A , Villarroya M , Lopez MG , Marco-Contelles J
Ref : Eur Journal of Medicinal Chemistry , 46 :4676 , 2011
Abstract : Silva_2011_Eur.J.Med.Chem_46_4676
ESTHER : Silva_2011_Eur.J.Med.Chem_46_4676
PubMedSearch : Silva_2011_Eur.J.Med.Chem_46_4676
PubMedID: 21715067

Title : Old phenothiazine and dibenzothiadiazepine derivatives for tomorrow's neuroprotective therapies against neurodegenerative diseases - Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152
Author(s) : Gonzalez-Munoz GC , Arce MP , Lopez B , Perez C , Villarroya M , Lopez MG , Garcia AG , Conde S , Rodriguez-Franco MI
Ref : Eur Journal of Medicinal Chemistry , 45 :6152 , 2010
Abstract : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152
ESTHER : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152
PubMedSearch : Gonzalez-Munoz_2010_Eur.J.Med.Chem_45_6152
PubMedID: 20926162

Title : Multipotent drugs with cholinergic and neuroprotective properties for the treatment of Alzheimer and neuronal vascular diseases. I. Synthesis, biological assessment, and molecular modeling of simple and readily available 2-aminopyridine-, and 2-chloropyridine-3,5-dicarbonitriles - Samadi_2010_Bioorg.Med.Chem_18_5861
Author(s) : Samadi A , Marco-Contelles J , Soriano E , Alvarez-Perez M , Chioua M , Romero A , Gonzalez-Lafuente L , Gandia L , Roda JM , Lopez MG , Villarroya M , Garcia AG , Rios Cde L
Ref : Bioorganic & Medicinal Chemistry , 18 :5861 , 2010
Abstract : Samadi_2010_Bioorg.Med.Chem_18_5861
ESTHER : Samadi_2010_Bioorg.Med.Chem_18_5861
PubMedSearch : Samadi_2010_Bioorg.Med.Chem_18_5861
PubMedID: 20656495

Title : Synthesis, inhibitory activity of cholinesterases, and neuroprotective profile of novel 1,8-naphthyridine derivatives - de Los Rios_2010_J.Med.Chem_53_5129
Author(s) : de los Rios C , Egea J , Marco-Contelles J , Leon R , Samadi A , Iriepa I , Moraleda I , Galvez E , Garcia AG , Lopez MG , Villarroya M , Romero A
Ref : Journal of Medicinal Chemistry , 53 :5129 , 2010
Abstract : de Los Rios_2010_J.Med.Chem_53_5129
ESTHER : de Los Rios_2010_J.Med.Chem_53_5129
PubMedSearch : de Los Rios_2010_J.Med.Chem_53_5129
PubMedID: 20575555

Title : Novel tacrine-8-hydroxyquinoline hybrids as multifunctional agents for the treatment of Alzheimer's disease, with neuroprotective, cholinergic, antioxidant, and copper-complexing properties - Fernandez-Bachiller_2010_J.Med.Chem_53_4927
Author(s) : Fernandez-Bachiller MI , Perez C , Gonzalez-Munoz GC , Conde S , Lopez MG , Villarroya M , Garcia AG , Rodriguez-Franco MI
Ref : Journal of Medicinal Chemistry , 53 :4927 , 2010
Abstract : Fernandez-Bachiller_2010_J.Med.Chem_53_4927
ESTHER : Fernandez-Bachiller_2010_J.Med.Chem_53_4927
PubMedSearch : Fernandez-Bachiller_2010_J.Med.Chem_53_4927
PubMedID: 20545360

Title : Synergistic neuroprotective effect of combined low concentrations of galantamine and melatonin against oxidative stress in SH-SY5Y neuroblastoma cells - Romero_2010_J.Pineal.Res_49_141
Author(s) : Romero A , Egea J , Garcia AG , Lopez MG
Ref : J Pineal Res , 49 :141 , 2010
Abstract : Romero_2010_J.Pineal.Res_49_141
ESTHER : Romero_2010_J.Pineal.Res_49_141
PubMedSearch : Romero_2010_J.Pineal.Res_49_141
PubMedID: 20536682

Title : Tacrine-melatonin hybrids as multifunctional agents for Alzheimer's disease, with cholinergic, antioxidant, and neuroprotective properties - Fernandez-Bachiller_2009_ChemMedChem_4_828
Author(s) : Fernandez-Bachiller MI , Perez C , Campillo NE , Paez JA , Gonzalez-Munoz GC , Usan P , Garcia-Palomero E , Lopez MG , Villarroya M , Garcia AG , Martinez A , Rodriguez-Franco MI
Ref : ChemMedChem , 4 :828 , 2009
Abstract : Fernandez-Bachiller_2009_ChemMedChem_4_828
ESTHER : Fernandez-Bachiller_2009_ChemMedChem_4_828
PubMedSearch : Fernandez-Bachiller_2009_ChemMedChem_4_828
PubMedID: 19308922

Title : Effects of memantine and galantamine given separately or in association, on memory and hippocampal neuronal loss after transient global cerebral ischemia in gerbils - Lorrio_2009_Brain.Res_1254_128
Author(s) : Lorrio S , Negredo P , Roda JM , Garcia AG , Lopez MG
Ref : Brain Research , 1254 :128 , 2009
Abstract : Lorrio_2009_Brain.Res_1254_128
ESTHER : Lorrio_2009_Brain.Res_1254_128
PubMedSearch : Lorrio_2009_Brain.Res_1254_128
PubMedID: 19103181

Title : Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease - Arce_2009_J.Med.Chem_52_7249
Author(s) : Arce MP , Rodriguez-Franco MI , Gonzalez-Munoz GC , Perez C , Lopez B , Villarroya M , Lopez MG , Garcia AG , Conde S
Ref : Journal of Medicinal Chemistry , 52 :7249 , 2009
Abstract : Arce_2009_J.Med.Chem_52_7249
ESTHER : Arce_2009_J.Med.Chem_52_7249
PubMedSearch : Arce_2009_J.Med.Chem_52_7249
PubMedID: 19856923

Title : New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties - Leon_2008_Bioorg.Med.Chem_16_7759
Author(s) : Leon R , de los Rios C , Marco-Contelles J , Huertas O , Barril X , Luque FJ , Lopez MG , Garcia AG , Villarroya M
Ref : Bioorganic & Medicinal Chemistry , 16 :7759 , 2008
Abstract : Leon_2008_Bioorg.Med.Chem_16_7759
ESTHER : Leon_2008_Bioorg.Med.Chem_16_7759
PubMedSearch : Leon_2008_Bioorg.Med.Chem_16_7759
PubMedID: 18640842

Title : An update on the pharmacology of galantamine - Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987
Author(s) : Villarroya M , Garcia AG , Marco-Contelles J , Lopez MG
Ref : Expert Opin Investig Drugs , 16 :1987 , 2007
Abstract : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987
ESTHER : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987
PubMedSearch : Villarroya_2007_Expert.Opin.Investig.Drugs_16_1987
PubMedID: 18042006

Title : Desensitized nicotinic receptors that, however, afford cytoprotection in bovine chromaffin cells - Egea_2006_J.Mol.Neurosci_30_59
Author(s) : Egea J , Hernandez-Guijo JM , Olivares R , Lopez MG , Garcia AG
Ref : Journal of Molecular Neuroscience , 30 :59 , 2006
Abstract : Egea_2006_J.Mol.Neurosci_30_59
ESTHER : Egea_2006_J.Mol.Neurosci_30_59
PubMedSearch : Egea_2006_J.Mol.Neurosci_30_59
PubMedID: 17192627

Title : Can cholinesterase inhibitors provide additional effects to cholinergic neurotransmission enhancement? - Lopez_2006_J.Mol.Neurosci_30_141
Author(s) : Lopez MG , Arias E , Sobrado M , Lorrio S , Roda JM , Garcia AG
Ref : Journal of Molecular Neuroscience , 30 :141 , 2006
Abstract : Lopez_2006_J.Mol.Neurosci_30_141
ESTHER : Lopez_2006_J.Mol.Neurosci_30_141
PubMedSearch : Lopez_2006_J.Mol.Neurosci_30_141
PubMedID: 17192661

Title : Novel multipotent tacrine-dihydropyridine hybrids with improved acetylcholinesterase inhibitory and neuroprotective activities as potential drugs for the treatment of Alzheimer's disease - Marco-Contelles_2006_J.Med.Chem_49_7607
Author(s) : Marco-Contelles J , Leon R , de los Rios C , Guglietta A , Terencio J , Lopez MG , Garcia AG , Villarroya M
Ref : Journal of Medicinal Chemistry , 49 :7607 , 2006
Abstract : Marco-Contelles_2006_J.Med.Chem_49_7607
ESTHER : Marco-Contelles_2006_J.Med.Chem_49_7607
PubMedSearch : Marco-Contelles_2006_J.Med.Chem_49_7607
PubMedID: 17181144

Title : Neuroprotection by nicotine in hippocampal slices subjected to oxygen-glucose deprivation: involvement of the alpha7 nAChR subtype - Rosa_2006_J.Mol.Neurosci_30_61
Author(s) : Rosa AO , Egea J , Gandia L , Lopez MG , Garcia AG
Ref : Journal of Molecular Neuroscience , 30 :61 , 2006
Abstract : Rosa_2006_J.Mol.Neurosci_30_61
ESTHER : Rosa_2006_J.Mol.Neurosci_30_61
PubMedSearch : Rosa_2006_J.Mol.Neurosci_30_61
PubMedID: 17192628

Title : Synthesis and biological evaluation of new 4H-pyrano[2,3-b]quinoline derivatives that block acetylcholinesterase and cell calcium signals, and cause neuroprotection against calcium overload and free radicals - Marco-Contelles_2006_Eur.J.Med.Chem_41_1464
Author(s) : Marco-Contelles J , Leon R , Lopez MG , Garcia AG , Villarroya M
Ref : Eur Journal of Medicinal Chemistry , 41 :1464 , 2006
Abstract : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464
ESTHER : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464
PubMedSearch : Marco-Contelles_2006_Eur.J.Med.Chem_41_1464
PubMedID: 17030484

Title : Blockade of Ca2+ -activated K+ channels by galantamine can also contribute to the potentiation of catecholamine secretion from chromaffin cells - Ales_2006_Eur.J.Pharmacol_548_45
Author(s) : Ales E , Gullo F , Arias E , Olivares R , Garcia AG , Wanke E , Lopez MG
Ref : European Journal of Pharmacology , 548 :45 , 2006
Abstract : Ales_2006_Eur.J.Pharmacol_548_45
ESTHER : Ales_2006_Eur.J.Pharmacol_548_45
PubMedSearch : Ales_2006_Eur.J.Pharmacol_548_45
PubMedID: 16949070

Title : Unequal neuroprotection afforded by the acetylcholinesterase inhibitors galantamine, donepezil, and rivastigmine in SH-SY5Y neuroblastoma cells: role of nicotinic receptors - Arias_2005_J.Pharmacol.Exp.Ther_315_1346
Author(s) : Arias E , Gallego-Sandin S , Villarroya M , Garcia AG , Lopez MG
Ref : Journal of Pharmacology & Experimental Therapeutics , 315 :1346 , 2005
Abstract : Arias_2005_J.Pharmacol.Exp.Ther_315_1346
ESTHER : Arias_2005_J.Pharmacol.Exp.Ther_315_1346
PubMedSearch : Arias_2005_J.Pharmacol.Exp.Ther_315_1346
PubMedID: 16144975

Title : Galantamine prevents apoptosis induced by beta-amyloid and thapsigargin: involvement of nicotinic acetylcholine receptors - Arias_2004_Neuropharmacol_46_103
Author(s) : Arias E , Ales E , Gabilan NH , Cano-Abad MF , Villarroya M , Garcia AG , Lopez MG
Ref : Neuropharmacology , 46 :103 , 2004
Abstract : Arias_2004_Neuropharmacol_46_103
ESTHER : Arias_2004_Neuropharmacol_46_103
PubMedSearch : Arias_2004_Neuropharmacol_46_103
PubMedID: 14654102

Title : ITH4012 (ethyl 5-amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylat e), a novel acetylcholinesterase inhibitor with calcium promotor and neuroprotective properties - Orozco_2004_J.Pharmacol.Exp.Ther_310_987
Author(s) : Orozco C , de los Rios C , Arias E , Leon R , Garcia AG , Marco JL , Villarroya M , Lopez MG
Ref : Journal of Pharmacology & Experimental Therapeutics , 310 :987 , 2004
Abstract : Orozco_2004_J.Pharmacol.Exp.Ther_310_987
ESTHER : Orozco_2004_J.Pharmacol.Exp.Ther_310_987
PubMedSearch : Orozco_2004_J.Pharmacol.Exp.Ther_310_987
PubMedID: 15111641

Title : Galantamine and memantine produce different degrees of neuroprotection in rat hippocampal slices subjected to oxygen-glucose deprivation - Sobrado_2004_Neurosci.Lett_365_132
Author(s) : Sobrado M , Roda JM , Lopez MG , Egea J , Garcia AG
Ref : Neuroscience Letters , 365 :132 , 2004
Abstract : Sobrado_2004_Neurosci.Lett_365_132
ESTHER : Sobrado_2004_Neurosci.Lett_365_132
PubMedSearch : Sobrado_2004_Neurosci.Lett_365_132
PubMedID: 15245794