Title : Identification and optimization of soluble epoxide hydrolase inhibitors with dual potency towards fatty acid amide hydrolase - Kodani_2018_Bioorg.Med.Chem.Lett_28_762 |
Author(s) : Kodani SD , Bhakta S , Hwang SH , Pakhomova S , Newcomer ME , Morisseau C , Hammock BD |
Ref : Bioorganic & Medicinal Chemistry Lett , 28 :762 , 2018 |
Abstract : |
PubMedSearch : Kodani_2018_Bioorg.Med.Chem.Lett_28_762 |
PubMedID: 29366648 |
Gene_locus related to this paper: human-EPHX2 |
Title : Optimized inhibitors of soluble epoxide hydrolase improve in vitro target residence time and in vivo efficacy - Lee_2014_J.Med.Chem_57_7016 |
Author(s) : Lee KS , Liu JY , Wagner KM , Pakhomova S , Dong H , Morisseau C , Fu SH , Yang J , Wang P , Ulu A , Mate CA , Nguyen LV , Hwang SH , Edin ML , Mara AA , Wulff H , Newcomer ME , Zeldin DC , Hammock BD |
Ref : Journal of Medicinal Chemistry , 57 :7016 , 2014 |
Abstract : |
PubMedSearch : Lee_2014_J.Med.Chem_57_7016 |
PubMedID: 25079952 |
Gene_locus related to this paper: human-EPHX2 |
Title : Inhibition of soluble epoxide hydrolase by fulvestrant and sulfoxides - Morisseau_2013_Bioorg.Med.Chem.Lett_23_3818 |
Author(s) : Morisseau C , Pakhomova S , Hwang SH , Newcomer ME , Hammock BD |
Ref : Bioorganic & Medicinal Chemistry Lett , 23 :3818 , 2013 |
Abstract : |
PubMedSearch : Morisseau_2013_Bioorg.Med.Chem.Lett_23_3818 |
PubMedID: 23684894 |
Gene_locus related to this paper: human-EPHX2 |
Title : Synthesis and structure-activity relationship of piperidine-derived non-urea soluble epoxide hydrolase inhibitors - Pecic_2013_Bioorg.Med.Chem.Lett_23_417 |
Author(s) : Pecic S , Pakhomova S , Newcomer ME , Morisseau C , Hammock BD , Zhu Z , Rinderspacher A , Deng SX |
Ref : Bioorganic & Medicinal Chemistry Lett , 23 :417 , 2013 |
Abstract : |
PubMedSearch : Pecic_2013_Bioorg.Med.Chem.Lett_23_417 |
PubMedID: 23237835 |
Gene_locus related to this paper: human-EPHX2 |