Pool WF

References (10)

Title : Metabolic disposition of the cognition activator tacrine in rats, dogs, and humans. Species comparisons - Pool_1997_Drug.Metab.Dispos_25_590
Author(s) : Pool WF , Reily MD , Bjorge SM , Woolf TF
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 25 :590 , 1997
Abstract :
PubMedSearch : Pool_1997_Drug.Metab.Dispos_25_590
PubMedID: 9152598

Title : Identification of a 3-hydroxylated tacrine metabolite in rat and man: metabolic profiling implications and pharmacology - Pool_1996_J.Med.Chem_39_3014
Author(s) : Pool WF , Woolf TF , Reily MD , Caprathe BW , Emmerling MR , Jaen JC
Ref : Journal of Medicinal Chemistry , 39 :3014 , 1996
Abstract :
PubMedSearch : Pool_1996_J.Med.Chem_39_3014
PubMedID: 8709135

Title : The effect of cytochromes P4501A induction and inhibition on the disposition of the cognition activator tacrine in rat hepatic preparations - Bezek_1996_Xenobiotica_26_935
Author(s) : Bezek S , Kukan M , Pool WF , Woolf TF
Ref : Xenobiotica , 26 :935 , 1996
Abstract :
PubMedSearch : Bezek_1996_Xenobiotica_26_935
PubMedID: 8893040

Title : Distribution of tacrine and metabolites in rat brain and plasma after single- and multiple-dose regimens. Evidence for accumulation of tacrine in brain tissue - McNally_1996_Drug.Metab.Dispos_24_628
Author(s) : McNally WP , Pool WF , Sinz MW , Dehart P , Ortwine DF , Huang CC , Chang T , Woolf TF
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 24 :628 , 1996
Abstract :
PubMedSearch : McNally_1996_Drug.Metab.Dispos_24_628
PubMedID: 8781777

Title : Species variation in the bioactivation of tacrine by hepatic microsomes - Madden_1995_Xenobiotica_25_103
Author(s) : Madden S , Spaldin V , Hayes RN , Woolf TF , Pool WF , Park BK
Ref : Xenobiotica , 25 :103 , 1995
Abstract :
PubMedSearch : Madden_1995_Xenobiotica_25_103
PubMedID: 7604602

Title : Stereoselective hydroxylation of tacrine in rats and humans - Hooper_1994_Drug.Metab.Dispos_22_719
Author(s) : Hooper WD , Pool WF , Woolf TF , Gal J
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 22 :719 , 1994
Abstract :
PubMedSearch : Hooper_1994_Drug.Metab.Dispos_22_719
PubMedID: 7835223

Title : The effect of enzyme inhibition on the metabolism and activation of tacrine by human liver microsomes - Spaldin_1994_Br.J.Clin.Pharmacol_38_15
Author(s) : Spaldin V , Madden S , Pool WF , Woolf TF , Park BK
Ref : British Journal of Clinical Pharmacology , 38 :15 , 1994
Abstract :
PubMedSearch : Spaldin_1994_Br.J.Clin.Pharmacol_38_15
PubMedID: 7946932

Title : Metabolic disposition of tacrine in primary suspensions of rat hepatocyte and in single-pass perfused liver: in vitro\/in vivo comparisons - Kukan_1994_Xenobiotica_24_1107
Author(s) : Kukan M , Bezek S , Pool WF , Woolf TF
Ref : Xenobiotica , 24 :1107 , 1994
Abstract :
PubMedSearch : Kukan_1994_Xenobiotica_24_1107
PubMedID: 7701852

Title : An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro. Studies with human and rat liver microsomes - Madden_1993_Biochem.Pharmacol_46_13
Author(s) : Madden S , Woolf TF , Pool WF , Park BK
Ref : Biochemical Pharmacology , 46 :13 , 1993
Abstract :
PubMedSearch : Madden_1993_Biochem.Pharmacol_46_13
PubMedID: 8347124

Title : Bioactivation and irreversible binding of the cognition activator tacrine using human and rat liver microsomal preparations. Species difference - Woolf_1993_Drug.Metab.Dispos_21_874
Author(s) : Woolf TF , Pool WF , Bjorge SM , Chang T , Goel OP , Purchase CF, 2nd , Schroeder MC , Kunze KL , Trager WF
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 21 :874 , 1993
Abstract :
PubMedSearch : Woolf_1993_Drug.Metab.Dispos_21_874
PubMedID: 7902251