Title : Caffeine based measures of CYP1A2 activity correlate with oral clearance of tacrine in patients with Alzheimer's disease - Fontana_1998_Br.J.Clin.Pharmacol_46_221 |
Author(s) : Fontana RJ , deVries TM , Woolf TF , Knapp MJ , Brown AS , Kaminsky LS , Tang BK , Foster NL , Brown RR , Watkins PB |
Ref : British Journal of Clinical Pharmacology , 46 :221 , 1998 |
PubMedID: 9764962 |
Title : Metabolic disposition of the cognition activator tacrine in rats, dogs, and humans. Species comparisons - Pool_1997_Drug.Metab.Dispos_25_590 |
Author(s) : Pool WF , Reily MD , Bjorge SM , Woolf TF |
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 25 :590 , 1997 |
PubMedID: 9152598 |
Title : Characterization of the induction of rat microsomal cytochrome P450 by tacrine - Sinz_1997_Biochem.Pharmacol_54_425 |
Author(s) : Sinz MW , Woolf TF |
Ref : Biochemical Pharmacology , 54 :425 , 1997 |
PubMedID: 9278102 |
Title : The caffeine breath test does not identify patients susceptible to tacrine hepatotoxicity - Fontana_1996_Hepatology_23_1429 |
Author(s) : Fontana RJ , Turgeon DK , Woolf TF , Knapp MJ , Foster NL , Watkins PB |
Ref : Hepatology , 23 :1429 , 1996 |
PubMedID: 8675160 |
Title : Identification of a 3-hydroxylated tacrine metabolite in rat and man: metabolic profiling implications and pharmacology - Pool_1996_J.Med.Chem_39_3014 |
Author(s) : Pool WF , Woolf TF , Reily MD , Caprathe BW , Emmerling MR , Jaen JC |
Ref : Journal of Medicinal Chemistry , 39 :3014 , 1996 |
PubMedID: 8709135 |
Title : Distribution of tacrine and metabolites in rat brain and plasma after single- and multiple-dose regimens. Evidence for accumulation of tacrine in brain tissue - McNally_1996_Drug.Metab.Dispos_24_628 |
Author(s) : McNally WP , Pool WF , Sinz MW , Dehart P , Ortwine DF , Huang CC , Chang T , Woolf TF |
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 24 :628 , 1996 |
PubMedID: 8781777 |
Title : An investigation into the formation of stable, protein-reactive and cytotoxic metabolites from tacrine in vitro. Studies with human and rat liver microsomes - Madden_1993_Biochem.Pharmacol_46_13 |
Author(s) : Madden S , Woolf TF , Pool WF , Park BK |
Ref : Biochemical Pharmacology , 46 :13 , 1993 |
PubMedID: 8347124 |
Title : Bioactivation and irreversible binding of the cognition activator tacrine using human and rat liver microsomal preparations. Species difference - Woolf_1993_Drug.Metab.Dispos_21_874 |
Author(s) : Woolf TF , Pool WF , Bjorge SM , Chang T , Goel OP , Purchase CF, 2nd , Schroeder MC , Kunze KL , Trager WF |
Ref : Drug Metabolism & Disposition: The Biological Fate of Chemicals , 21 :874 , 1993 |
PubMedID: 7902251 |