Title : The synthesis and structure-activity relationship of substituted N-phenyl anthranilic acid analogs as amyloid aggregation inhibitors - Simons_2009_Bioorg.Med.Chem.Lett_19_654 |
Author(s) : Simons LJ , Caprathe BW , Callahan M , Graham JM , Kimura T , Lai Y , LeVine H, 3rd , Lipinski W , Sakkab AT , Tasaki Y , Walker LC , Yasunaga T , Ye Y , Zhuang N , Augelli-Szafran CE |
Ref : Bioorganic & Medicinal Chemistry Lett , 19 :654 , 2009 |
Abstract : |
PubMedSearch : Simons_2009_Bioorg.Med.Chem.Lett_19_654 |
PubMedID: 19121939 |
Title : CI-1017, a functionally M1-selective muscarinic agonist: design, synthesis, and preclinical pharmacology - Tecle_2000_Pharm.Acta.Helv_74_141 |
Author(s) : Tecle H , Schwarz RD , Barrett SD , Callahan MJ , Caprathe BW , Davis RE , Doyle P , Emmerling M , Lauffer DJ , Mirzadegan T , Moreland DW , Lipiniski W , Nelson C , Raby C , Spencer C , Spiegel K , Thomas AJ , Jaen JC |
Ref : Pharm Acta Helv , 74 :141 , 2000 |
Abstract : |
PubMedSearch : Tecle_2000_Pharm.Acta.Helv_74_141 |
PubMedID: 10812951 |
Title : Design and synthesis of m1-selective muscarinic agonists: (R)-(-)-(Z)-1-Azabicyclo[2.2.1]heptan-3-one, O-(3-(3'-methoxyphenyl)-2-propynyl)oxime maleate (CI-1017), a functionally m1-selective muscarinic agonist - Tecle_1998_J.Med.Chem_41_2524 |
Author(s) : Tecle H , Barrett SD , Lauffer DJ , Augelli-Szafran C , Brann MR , Callahan MJ , Caprathe BW , Davis RE , Doyle PD , Eubanks D , Lipiniski W , Mirzadegan T , Moos WH , Moreland DW , Nelson CB , Pavia MR , Raby C , Schwarz RD , Spencer CJ , Thomas AJ , Jaen JC |
Ref : Journal of Medicinal Chemistry , 41 :2524 , 1998 |
Abstract : |
PubMedSearch : Tecle_1998_J.Med.Chem_41_2524 |
PubMedID: 9651157 |
Title : Identification of a 3-hydroxylated tacrine metabolite in rat and man: metabolic profiling implications and pharmacology - Pool_1996_J.Med.Chem_39_3014 |
Author(s) : Pool WF , Woolf TF , Reily MD , Caprathe BW , Emmerling MR , Jaen JC |
Ref : Journal of Medicinal Chemistry , 39 :3014 , 1996 |
Abstract : |
PubMedSearch : Pool_1996_J.Med.Chem_39_3014 |
PubMedID: 8709135 |