Full name : Saccone Nancy L
First name : Nancy L
Mail : Department of Genetics, Washington University School of Medicine, St. Louis, MO
Zip Code :
City :
Country : USA
Email : nlims@wustl.edu
Phone :
Fax :
Website : \/\/dbbs.wustl.edu\/faculty\/Pages\/faculty_bio.aspx?SID=5824
Directory :
Comment
Title : Rare, low frequency and common coding variants in CHRNA5 and their contribution to nicotine dependence in European and African Americans - Olfson_2016_Mol.Psychiatry_21_601 |
Author(s) : Olfson E , Saccone NL , Johnson EO , Chen LS , Culverhouse R , Doheny K , Foltz SM , Fox L , Gogarten SM , Hartz S , Hetrick K , Laurie CC , Marosy B , Amin N , Arnett D , Barr RG , Bartz TM , Bertelsen S , Borecki IB , Brown MR , Chasman DI , van Duijn CM , Feitosa MF , Fox ER , Franceschini N , Franco OH , Grove ML , Guo X , Hofman A , Kardia SL , Morrison AC , Musani SK , Psaty BM , Rao DC , Reiner AP , Rice K , Ridker PM , Rose LM , Schick UM , Schwander K , Uitterlinden AG , Vojinovic D , Wang JC , Ware EB , Wilson G , Yao J , Zhao W , Breslau N , Hatsukami D , Stitzel JA , Rice J , Goate A , Bierut LJ |
Ref : Mol Psychiatry , 21 :601 , 2016 |
Abstract : |
PubMedSearch : Olfson_2016_Mol.Psychiatry_21_601 |
PubMedID: 26239294 |
Title : Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence - Hancock_2015_Transl.Psychiatry_5_e651 |
Author(s) : Hancock DB , Reginsson GW , Gaddis NC , Chen X , Saccone NL , Lutz SM , Qaiser B , Sherva R , Steinberg S , Zink F , Stacey SN , Glasheen C , Chen J , Gu F , Frederiksen BN , Loukola A , Gudbjartsson DF , Bruske I , Landi MT , Bickeboller H , Madden P , Farrer L , Kaprio J , Kranzler HR , Gelernter J , Baker TB , Kraft P , Amos CI , Caporaso NE , Hokanson JE , Bierut LJ , Thorgeirsson TE , Johnson EO , Stefansson K |
Ref : Transl Psychiatry , 5 :e651 , 2015 |
Abstract : |
PubMedSearch : Hancock_2015_Transl.Psychiatry_5_e651 |
PubMedID: 26440539 |
Title : A multiancestry study identifies novel genetic associations with CHRNA5 methylation in human brain and risk of nicotine dependence - Hancock_2015_Hum.Mol.Genet_24_5940 |
Author(s) : Hancock DB , Wang JC , Gaddis NC , Levy JL , Saccone NL , Stitzel JA , Goate A , Bierut LJ , Johnson EO |
Ref : Hum Mol Genet , 24 :5940 , 2015 |
Abstract : |
PubMedSearch : Hancock_2015_Hum.Mol.Genet_24_5940 |
PubMedID: 26220977 |
Title : Multiple distinct CHRNB3-CHRNA6 variants are genetic risk factors for nicotine dependence in African Americans and European Americans - Culverhouse_2014_Addiction_109_814 |
Author(s) : Culverhouse RC , Johnson EO , Breslau N , Hatsukami DK , Sadler B , Brooks AI , Hesselbrock VM , Schuckit MA , Tischfield JA , Goate AM , Saccone NL , Bierut LJ |
Ref : Addiction , 109 :814 , 2014 |
Abstract : |
PubMedSearch : Culverhouse_2014_Addiction_109_814 |
PubMedID: 24401102 |
Title : Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence - Haller_2014_Hum.Mol.Genet_23_810 |
Author(s) : Haller G , Kapoor M , Budde J , Xuei X , Edenberg H , Nurnberger J , Kramer J , Brooks A , Tischfield J , Almasy L , Agrawal A , Bucholz K , Rice J , Saccone NL , Bierut L , Goate A |
Ref : Hum Mol Genet , 23 :810 , 2014 |
Abstract : |
PubMedSearch : Haller_2014_Hum.Mol.Genet_23_810 |
PubMedID: 24057674 |
Title : A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks - Kapoor_2013_Hum.Genet_132_1141 |
Author(s) : Kapoor M , Wang JC , Wetherill L , Le N , Bertelsen S , Hinrichs AL , Budde J , Agrawal A , Bucholz K , Dick D , Harari O , Hesselbrock V , Kramer J , Nurnberger JI, Jr. , Rice J , Saccone NL , Schuckit M , Tischfield J , Porjesz B , Edenberg HJ , Bierut L , Foroud T , Goate A |
Ref : Hum Genet , 132 :1141 , 2013 |
Abstract : |
PubMedSearch : Kapoor_2013_Hum.Genet_132_1141 |
PubMedID: 23743675 |
Title : Dissection of the phenotypic and genotypic associations with nicotinic dependence - Chen_2012_Nicotine.Tob.Res_14_425 |
Author(s) : Chen LS , Baker TB , Grucza R , Wang JC , Johnson EO , Breslau N , Hatsukami D , Smith SS , Saccone NL , Saccone S , Rice JP , Goate AM , Bierut LJ |
Ref : Nicotine Tob Res , 14 :425 , 2012 |
Abstract : |
PubMedSearch : Chen_2012_Nicotine.Tob.Res_14_425 |
PubMedID: 22102629 |
Title : Interplay of genetic risk factors (CHRNA5-CHRNA3-CHRNB4) and cessation treatments in smoking cessation success - Chen_2012_Am.J.Psychiatry_169_735 |
Author(s) : Chen LS , Baker TB , Piper ME , Breslau N , Cannon DS , Doheny KF , Gogarten SM , Johnson EO , Saccone NL , Wang JC , Weiss RB , Goate AM , Bierut LJ |
Ref : Am J Psychiatry , 169 :735 , 2012 |
Abstract : |
PubMedSearch : Chen_2012_Am.J.Psychiatry_169_735 |
PubMedID: 22648373 |
Title : Nicotine dependence and comorbid psychiatric disorders: examination of specific genetic variants in the CHRNA5-A3-B4 nicotinic receptor genes - Chen_2012_Drug.Alcohol.Depend_123 Suppl 1_S42 |
Author(s) : Chen LS , Xian H , Grucza RA , Saccone NL , Wang JC , Johnson EO , Breslau N , Hatsukami D , Bierut LJ |
Ref : Drug Alcohol Depend , 123 Suppl 1 :S42 , 2012 |
Abstract : |
PubMedSearch : Chen_2012_Drug.Alcohol.Depend_123 Suppl 1_S42 |
PubMedID: 22336398 |
Title : CHRNB3 is more strongly associated with Fagerstrom test for cigarette dependence-based nicotine dependence than cigarettes per day: phenotype definition changes genome-wide association studies results - Rice_2012_Addiction_107_2019 |
Author(s) : Rice JP , Hartz SM , Agrawal A , Almasy L , Bennett S , Breslau N , Bucholz KK , Doheny KF , Edenberg HJ , Goate AM , Hesselbrock V , Howells WB , Johnson EO , Kramer J , Krueger RF , Kuperman S , Laurie C , Manolio TA , Neuman RJ , Nurnberger JI , Porjesz B , Pugh E , Ramos EM , Saccone NL , Saccone S , Schuckit M , Bierut LJ |
Ref : Addiction , 107 :2019 , 2012 |
Abstract : |
PubMedSearch : Rice_2012_Addiction_107_2019 |
PubMedID: 22524403 |
Title : Incorporating age at onset of smoking into genetic models for nicotine dependence: evidence for interaction with multiple genes - Grucza_2010_Addict.Biol_15_346 |
Author(s) : Grucza RA , Johnson EO , Krueger RF , Breslau N , Saccone NL , Chen LS , Derringer J , Agrawal A , Lynskey M , Bierut LJ |
Ref : Addict Biol , 15 :346 , 2010 |
Abstract : |
PubMedSearch : Grucza_2010_Addict.Biol_15_346 |
PubMedID: 20624154 |
Title : Association of CHRN genes with dizziness to tobacco - Ehringer_2010_Am.J.Med.Genet.B.Neuropsychiatr.Genet_153B_600 |
Author(s) : Ehringer MA , McQueen MB , Hoft NR , Saccone NL , Stitzel JA , Wang JC , Bierut LJ |
Ref : American Journal of Medicine Genet B Neuropsychiatr Genet , 153B :600 , 2010 |
Abstract : |
PubMedSearch : Ehringer_2010_Am.J.Med.Genet.B.Neuropsychiatr.Genet_153B_600 |
PubMedID: 19760673 |
Title : Peer smoking and the nicotinic receptor genes: an examination of genetic and environmental risks for nicotine dependence - Johnson_2010_Addiction_105_2014 |
Author(s) : Johnson EO , Chen LS , Breslau N , Hatsukami D , Robbins T , Saccone NL , Grucza RA , Bierut LJ |
Ref : Addiction , 105 :2014 , 2010 |
Abstract : |
PubMedSearch : Johnson_2010_Addiction_105_2014 |
PubMedID: 20840187 |
Title : Multiple cholinergic nicotinic receptor genes affect nicotine dependence risk in African and European Americans - Saccone_2010_Genes.Brain.Behav_9_741 |
Author(s) : Saccone NL , Schwantes-An TH , Wang JC , Grucza RA , Breslau N , Hatsukami D , Johnson EO , Rice JP , Goate AM , Bierut LJ |
Ref : Genes Brain Behav , 9 :741 , 2010 |
Abstract : |
PubMedSearch : Saccone_2010_Genes.Brain.Behav_9_741 |
PubMedID: 20584212 |
Title : Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5 - Wang_2009_Hum.Mol.Genet_18_3125 |
Author(s) : Wang JC , Cruchaga C , Saccone NL , Bertelsen S , Liu P , Budde JP , Duan W , Fox L , Grucza RA , Kern J , Mayo K , Reyes O , Rice J , Saccone SF , Spiegel N , Steinbach JH , Stitzel JA , Anderson MW , You M , Stevens VL , Bierut LJ , Goate AM |
Ref : Hum Mol Genet , 18 :3125 , 2009 |
Abstract : |
PubMedSearch : Wang_2009_Hum.Mol.Genet_18_3125 |
PubMedID: 19443489 |
Title : Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence - Wang_2009_Mol.Psychiatry_14_501 |
Author(s) : Wang JC , Grucza R , Cruchaga C , Hinrichs AL , Bertelsen S , Budde JP , Fox L , Goldstein E , Reyes O , Saccone NL , Saccone S , Xuei X , Bucholz K , Kuperman S , Nurnberger J, Jr. , Rice JP , Schuckit M , Tischfield J , Hesselbrock V , Porjesz B , Edenberg HJ , Bierut LJ , Goate AM |
Ref : Mol Psychiatry , 14 :501 , 2009 |
Abstract : |
PubMedSearch : Wang_2009_Mol.Psychiatry_14_501 |
PubMedID: 18414406 |
Title : Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerstrom Test for Nicotine Dependence - Agrawal_2009_Addiction_104_471 |
Author(s) : Agrawal A , Pergadia ML , Balasubramanian S , Saccone SF , Hinrichs AL , Saccone NL , Breslau N , Johnson EO , Hatsukami D , Martin NG , Montgomery GW , Goate AM , Rice JP , Bierut LJ , Madden PA |
Ref : Addiction , 104 :471 , 2009 |
Abstract : |
PubMedSearch : Agrawal_2009_Addiction_104_471 |
PubMedID: 19207358 |
Title : A testable prognostic model of nicotine dependence - Ramoni_2009_J.Neurogenet_23_283 |
Author(s) : Ramoni RB , Saccone NL , Hatsukami DK , Bierut LJ , Ramoni MF |
Ref : J Neurogenet , 23 :283 , 2009 |
Abstract : |
PubMedSearch : Ramoni_2009_J.Neurogenet_23_283 |
PubMedID: 19184766 |
Title : Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes - Saccone_2009_Am.J.Med.Genet.B.Neuropsychiatr.Genet_150B_453 |
Author(s) : Saccone NL , Saccone SF , Hinrichs AL , Stitzel JA , Duan W , Pergadia ML , Agrawal A , Breslau N , Grucza RA , Hatsukami D , Johnson EO , Madden PA , Swan GE , Wang JC , Goate AM , Rice JP , Bierut LJ |
Ref : American Journal of Medicine Genet B Neuropsychiatr Genet , 150B :453 , 2009 |
Abstract : |
PubMedSearch : Saccone_2009_Am.J.Med.Genet.B.Neuropsychiatr.Genet_150B_453 |
PubMedID: 19259974 |
Title : The CHRNA5-CHRNA3-CHRNB4 nicotinic receptor subunit gene cluster affects risk for nicotine dependence in African-Americans and in European-Americans - Saccone_2009_Cancer.Res_69_6848 |
Author(s) : Saccone NL , Wang JC , Breslau N , Johnson EO , Hatsukami D , Saccone SF , Grucza RA , Sun L , Duan W , Budde J , Culverhouse RC , Fox L , Hinrichs AL , Steinbach JH , Wu M , Rice JP , Goate AM , Bierut LJ |
Ref : Cancer Research , 69 :6848 , 2009 |
Abstract : |
PubMedSearch : Saccone_2009_Cancer.Res_69_6848 |
PubMedID: 19706762 |
Title : A risk allele for nicotine dependence in CHRNA5 is a protective allele for cocaine dependence - Grucza_2008_Biol.Psychiatry_64_922 |
Author(s) : Grucza RA , Wang JC , Stitzel JA , Hinrichs AL , Saccone SF , Saccone NL , Bucholz KK , Cloninger CR , Neuman RJ , Budde JP , Fox L , Bertelsen S , Kramer J , Hesselbrock V , Tischfield J , Nurnberger JI, Jr. , Almasy L , Porjesz B , Kuperman S , Schuckit MA , Edenberg HJ , Rice JP , Goate AM , Bierut LJ |
Ref : Biological Psychiatry , 64 :922 , 2008 |
Abstract : |
PubMedSearch : Grucza_2008_Biol.Psychiatry_64_922 |
PubMedID: 18519132 |
Title : Variants in nicotinic receptors and risk for nicotine dependence - Bierut_2008_Am.J.Psychiatry_165_1163 |
Author(s) : Bierut LJ , Stitzel JA , Wang JC , Hinrichs AL , Grucza RA , Xuei X , Saccone NL , Saccone SF , Bertelsen S , Fox L , Horton WJ , Breslau N , Budde J , Cloninger CR , Dick DM , Foroud T , Hatsukami D , Hesselbrock V , Johnson EO , Kramer J , Kuperman S , Madden PA , Mayo K , Nurnberger J, Jr. , Pomerleau O , Porjesz B , Reyes O , Schuckit M , Swan G , Tischfield JA , Edenberg HJ , Rice JP , Goate AM |
Ref : Am J Psychiatry , 165 :1163 , 2008 |
Abstract : |
PubMedSearch : Bierut_2008_Am.J.Psychiatry_165_1163 |
PubMedID: 18519524 |
Title : Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence - Saccone_2008_Bioinformatics_24_1805 |
Author(s) : Saccone SF , Saccone NL , Swan GE , Madden PA , Goate AM , Rice JP , Bierut LJ |
Ref : Bioinformatics , 24 :1805 , 2008 |
Abstract : |
PubMedSearch : Saccone_2008_Bioinformatics_24_1805 |
PubMedID: 18565990 |
Title : Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs - Saccone_2007_Hum.Mol.Genet_16_36 |
Author(s) : Saccone SF , Hinrichs AL , Saccone NL , Chase GA , Konvicka K , Madden PA , Breslau N , Johnson EO , Hatsukami D , Pomerleau O , Swan GE , Goate AM , Rutter J , Bertelsen S , Fox L , Fugman D , Martin NG , Montgomery GW , Wang JC , Ballinger DG , Rice JP , Bierut LJ |
Ref : Hum Mol Genet , 16 :36 , 2007 |
Abstract : |
PubMedSearch : Saccone_2007_Hum.Mol.Genet_16_36 |
PubMedID: 17135278 |