| Title : Development of a photoactivatable allosteric ligand for the m1 muscarinic acetylcholine receptor - Davie_2014_ACS.Chem.Neurosci_5_902 |
| Author(s) : Davie BJ , Sexton PM , Capuano B , Christopoulos A , Scammells PJ |
| Ref : ACS Chem Neurosci , 5 :902 , 2014 |
| Abstract : |
| PubMedSearch : Davie_2014_ACS.Chem.Neurosci_5_902 |
| PubMedID: 25188871 |
| Title : Synthesis and pharmacological profiling of analogues of benzyl quinolone carboxylic acid (BQCA) as allosteric modulators of the M1 muscarinic receptor - Mistry_2013_J.Med.Chem_56_5151 |
| Author(s) : Mistry SN , Valant C , Sexton PM , Capuano B , Christopoulos A , Scammells PJ |
| Ref : Journal of Medicinal Chemistry , 56 :5151 , 2013 |
| Abstract : |
| PubMedSearch : Mistry_2013_J.Med.Chem_56_5151 |
| PubMedID: 23718562 |
| Title : Development of M1 mAChR allosteric and bitopic ligands: prospective therapeutics for the treatment of cognitive deficits - Davie_2013_ACS.Chem.Neurosci_4_1026 |
| Author(s) : Davie BJ , Christopoulos A , Scammells PJ |
| Ref : ACS Chem Neurosci , 4 :1026 , 2013 |
| Abstract : |
| PubMedSearch : Davie_2013_ACS.Chem.Neurosci_4_1026 |
| PubMedID: 23659787 |
| Title : Reverse engineering of the selective agonist TBPB unveils both orthosteric and allosteric modes of action at the M(1) muscarinic acetylcholine receptor - Keov_2013_Mol.Pharmacol_84_425 |
| Author(s) : Keov P , Valant C , Devine SM , Lane JR , Scammells PJ , Sexton PM , Christopoulos A |
| Ref : Molecular Pharmacology , 84 :425 , 2013 |
| Abstract : |
| PubMedSearch : Keov_2013_Mol.Pharmacol_84_425 |
| PubMedID: 23798605 |
| Title : A Monod-Wyman-Changeux mechanism can explain G protein-coupled receptor (GPCR) allosteric modulation - Canals_2012_J.Biol.Chem_287_650 |
| Author(s) : Canals M , Lane JR , Wen A , Scammells PJ , Sexton PM , Christopoulos A |
| Ref : Journal of Biological Chemistry , 287 :650 , 2012 |
| Abstract : |
| PubMedSearch : Canals_2012_J.Biol.Chem_287_650 |
| PubMedID: 22086918 |
| Title : Determination of adenosine A1 receptor agonist and antagonist pharmacology using Saccharomyces cerevisiae: implications for ligand screening and functional selectivity - Stewart_2009_J.Pharmacol.Exp.Ther_331_277 |
| Author(s) : Stewart GD , Valant C , Dowell SJ , Mijaljica D , Devenish RJ , Scammells PJ , Sexton PM , Christopoulos A |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 331 :277 , 2009 |
| Abstract : |
| PubMedSearch : Stewart_2009_J.Pharmacol.Exp.Ther_331_277 |
| PubMedID: 19641164 |
| Title : A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric\/allosteric ligand - Valant_2008_J.Biol.Chem_283_29312 |
| Author(s) : Valant C , Gregory KJ , Hall NE , Scammells PJ , Lew MJ , Sexton PM , Christopoulos A |
| Ref : Journal of Biological Chemistry , 283 :29312 , 2008 |
| Abstract : |
| PubMedSearch : Valant_2008_J.Biol.Chem_283_29312 |
| PubMedID: 18723515 |