Schacherer J

References (2)

Title : Genome Sequence of the Yeast Cyberlindnera fabianii (Hansenula fabianii) - Freel_2014_Genome.Announc_2_e00638
Author(s) : Freel KC , Sarilar V , Neuveglise C , Devillers H , Friedrich A , Schacherer J
Ref : Genome Announc , 2 : , 2014
Abstract : The yeast Cyberlindnera fabianii is used in wastewater treatment, fermentation of alcoholic beverages, and has caused blood infections. To assist in the accurate identification of this species, and to determine the genetic basis for properties involved in fermentation and water treatment, we sequenced and annotated the genome of C. fabianii (YJS4271).
ESTHER : Freel_2014_Genome.Announc_2_e00638
PubMedSearch : Freel_2014_Genome.Announc_2_e00638
PubMedID: 25103752
Gene_locus related to this paper: cybfa-a0a061b0q2 , cybfa-a0a061ayy2 , cybfa-a0a061b6j0

Title : Pichia sorbitophila, an Interspecies Yeast Hybrid, Reveals Early Steps of Genome Resolution After Polyploidization - Louis_2012_G3.(Bethesda)_2_299
Author(s) : Louis VL , Despons L , Friedrich A , Martin T , Durrens P , Casaregola S , Neuveglise C , Fairhead C , Marck C , Cruz JA , Straub ML , Kugler V , Sacerdot C , Uzunov Z , Thierry A , Weiss S , Bleykasten C , De Montigny J , Jacques N , Jung P , Lemaire M , Mallet S , Morel G , Richard GF , Sarkar A , Savel G , Schacherer J , Seret ML , Talla E , Samson G , Jubin C , Poulain J , Vacherie B , Barbe V , Pelletier E , Sherman DJ , Westhof E , Weissenbach J , Baret PV , Wincker P , Gaillardin C , Dujon B , Souciet JL
Ref : G3 (Bethesda) , 2 :299 , 2012
Abstract : Polyploidization is an important process in the evolution of eukaryotic genomes, but ensuing molecular mechanisms remain to be clarified. Autopolyploidization or whole-genome duplication events frequently are resolved in resulting lineages by the loss of single genes from most duplicated pairs, causing transient gene dosage imbalance and accelerating speciation through meiotic infertility. Allopolyploidization or formation of interspecies hybrids raises the problem of genetic incompatibility (Bateson-Dobzhansky-Muller effect) and may be resolved by the accumulation of mutational changes in resulting lineages. In this article, we show that an osmotolerant yeast species, Pichia sorbitophila, recently isolated in a concentrated sorbitol solution in industry, illustrates this last situation. Its genome is a mosaic of homologous and homeologous chromosomes, or parts thereof, that corresponds to a recently formed hybrid in the process of evolution. The respective parental contributions to this genome were characterized using existing variations in GC content. The genomic changes that occurred during the short period since hybrid formation were identified (e.g., loss of heterozygosity, unilateral loss of rDNA, reciprocal exchange) and distinguished from those undergone by the two parental genomes after separation from their common ancestor (i.e., NUMT (NUclear sequences of MiTochondrial origin) insertions, gene acquisitions, gene location movements, reciprocal translocation). We found that the physiological characteristics of this new yeast species are determined by specific but unequal contributions of its two parents, one of which could be identified as very closely related to an extant Pichia farinosa strain.
ESTHER : Louis_2012_G3.(Bethesda)_2_299
PubMedSearch : Louis_2012_G3.(Bethesda)_2_299
PubMedID: 22384408
Gene_locus related to this paper: picso-g8ycc9 , picso-g8yet0 , picso-g8yb96 , picso-g8ym39 , erecy-g8jrp5 , picso-g8y652