Title : Synthesis and biological evaluation of deferiprone-resveratrol hybrids as antioxidants, Abeta(1-42) aggregation inhibitors and metal-chelating agents for Alzheimer's disease - Xu_2017_Eur.J.Med.Chem_127_174 |
Author(s) : Xu P , Zhang M , Sheng R , Ma Y |
Ref : Eur Journal of Medicinal Chemistry , 127 :174 , 2017 |
PubMedID: 28061347 |
Title : Design, synthesis and evaluation of rivastigmine and curcumin hybrids as site-activated multitarget-directed ligands for Alzheimer's disease therapy - Li_2014_Bioorg.Med.Chem_22_4717 |
Author(s) : Li Y , Peng P , Tang L , Hu Y , Sheng R |
Ref : Bioorganic & Medicinal Chemistry , 22 :4717 , 2014 |
PubMedID: 25082512 |
Title : Evaluation of blood-brain barrier and blood-cerebrospinal fluid barrier permeability of 2-phenoxy-indan-1-one derivatives using in vitro cell models - Hu_2013_Int.J.Pharm_460_101 |
Author(s) : Hu HH , Bian YC , Liu Y , Sheng R , Jiang HD , Yu LS , Hu YZ , Zeng S |
Ref : Int J Pharm , 460 :101 , 2013 |
PubMedID: 24262988 |
Title : Searching for the Multi-Target-Directed Ligands against Alzheimer's disease: discovery of quinoxaline-based hybrid compounds with AChE, H(3)R and BACE 1 inhibitory activities - Huang_2011_Bioorg.Med.Chem_19_7158 |
Author(s) : Huang W , Tang L , Shi Y , Huang S , Xu L , Sheng R , Wu P , Li J , Zhou N , Hu Y |
Ref : Bioorganic & Medicinal Chemistry , 19 :7158 , 2011 |
PubMedID: 22019465 |
Title : Synthesis and biological evaluation of novel flavonoid derivatives as dual binding acetylcholinesterase inhibitors - Shen_2009_J.Enzyme.Inhib.Med.Chem_24_372 |
Author(s) : Shen Y , Zhang J , Sheng R , Dong X , He Q , Yang B , Hu Y |
Ref : J Enzyme Inhib Med Chem , 24 :372 , 2009 |
PubMedID: 18830885 |
Title : BZYX, a novel acetylcholinesterase inhibitor, significantly improved chemicals-induced learning and memory impairments on rodents and protected PC12 cells from apoptosis induced by hydrogen peroxide - Zhang_2009_Eur.J.Pharmacol_613_1 |
Author(s) : Zhang J , Zhu D , Sheng R , Wu H , Hu Y , Wang F , Cai T , Yang B , He Q |
Ref : European Journal of Pharmacology , 613 :1 , 2009 |
PubMedID: 19345205 |
Title : 2-Phenoxy-indan-1-one derivatives as acetylcholinesterase inhibitors: a study on the importance of modifications at the side chain on the activity - Shen_2008_Bioorg.Med.Chem_16_7646 |
Author(s) : Shen Y , Sheng R , Zhang J , He Q , Yang B , Hu Y |
Ref : Bioorganic & Medicinal Chemistry , 16 :7646 , 2008 |
PubMedID: 18662884 |