| Title : Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT(4) receptors with potential interest in the treatment of Alzheimer's disease - Rochais_2024_Eur.J.Med.Chem_280_116975 |
| Author(s) : Rochais C , Lecoutey C , Lalut J , Davis A , Duval E , Gaven F , Largilliere S , Nee G , Corvaisier S , Sopkova de Oliveira Santos J , Since M , Freret T , Legrand R , Callizot N , Claeysen S , Boulouard M , Dallemagne P |
| Ref : Eur Journal of Medicinal Chemistry , 280 :116975 , 2024 |
| Abstract : |
| PubMedSearch : Rochais_2024_Eur.J.Med.Chem_280_116975 |
| PubMedID: 39454222 |
| Title : Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT(6) receptor antagonist with therapeutic interest in Alzheimer's disease - Toublet_2020_Eur.J.Med.Chem_210_113059 |
| Author(s) : Toublet FX , Lalut J , Hatat B , Lecoutey C , Davis A , Since M , Corvaisier S , Freret T , Sopkova-de Oliveira Santos J , Claeysen S , Boulouard M , Dallemagne P , Rochais C |
| Ref : Eur Journal of Medicinal Chemistry , 210 :113059 , 2020 |
| Abstract : |
| PubMedSearch : Toublet_2020_Eur.J.Med.Chem_210_113059 |
| PubMedID: 33310288 |
| Title : Pharmacotechnical Development of a Nasal Drug Delivery Composite Nanosystem Intended for Alzheimer's Disease Treatment - Adnet_2020_Pharmaceutics_12_ |
| Author(s) : Adnet T , Groo AC , Picard C , Davis A , Corvaisier S , Since M , Bounoure F , Rochais C , Pluart LL , Dallemagne P , Malzert-Freon A |
| Ref : Pharmaceutics , 12 : , 2020 |
| Abstract : |
| PubMedSearch : Adnet_2020_Pharmaceutics_12_ |
| PubMedID: 32168767 |
| Title : Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease - Toublet_2019_Molecules_24_ |
| Author(s) : Toublet FX , Lecoutey C , Lalut J , Hatat B , Davis A , Since M , Corvaisier S , Freret T , Sopkova de Oliveira Santos J , Claeysen S , Boulouard M , Dallemagne P , Rochais C |
| Ref : Molecules , 24 : , 2019 |
| Abstract : |
| PubMedSearch : Toublet_2019_Molecules_24_ |
| PubMedID: 31370232 |
| Title : Benzylphenylpyrrolizinones with Anti-amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment - Jourdan_2017_ChemMedChem_12_913 |
| Author(s) : Jourdan JP , Since M , El Kihel L , Lecoutey C , Corvaisier S , Legay R , Sopkova-de Oliveira Santos J , Cresteil T , Malzert-Freon A , Rochais C , Dallemagne P |
| Ref : ChemMedChem , 12 :913 , 2017 |
| Abstract : |
| PubMedSearch : Jourdan_2017_ChemMedChem_12_913 |
| PubMedID: 28342294 |
| Title : Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment - Jourdan_2016_Eur.J.Med.Chem_114_365 |
| Author(s) : Jourdan JP , Since M , El Kihel L , Lecoutey C , Corvaisier S , Legay R , Sopkova-de Oliveira Santos J , Cresteil T , Malzert-Freon A , Rochais C , Dallemagne P |
| Ref : Eur Journal of Medicinal Chemistry , 114 :365 , 2016 |
| Abstract : |
| PubMedSearch : Jourdan_2016_Eur.J.Med.Chem_114_365 |
| PubMedID: 27046230 |
| Title : Synthesis and evaluation of novel serotonin 4 receptor radiotracers for single photon emission computed tomography - Lalut_2016_Eur.J.Med.Chem_116_90 |
| Author(s) : Lalut J , Tournier BB , Cailly T , Lecoutey C , Corvaisier S , Davis A , Ballandonne C , Since M , Millet P , Fabis F , Dallemagne P , Rochais C |
| Ref : Eur Journal of Medicinal Chemistry , 116 :90 , 2016 |
| Abstract : |
| PubMedSearch : Lalut_2016_Eur.J.Med.Chem_116_90 |
| PubMedID: 27060761 |
| Title : Design of donecopride, a dual serotonin subtype 4 receptor agonist\/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment - Lecoutey_2014_Proc.Natl.Acad.Sci.U.S.A_111_E3825 |
| Author(s) : Lecoutey C , Hedou D , Freret T , Giannoni P , Gaven F , Since M , Bouet V , Ballandonne C , Corvaisier S , Malzert Freon A , Mignani S , Cresteil T , Boulouard M , Claeysen S , Rochais C , Dallemagne P |
| Ref : Proc Natl Acad Sci U S A , 111 :E3825 , 2014 |
| Abstract : |
| PubMedSearch : Lecoutey_2014_Proc.Natl.Acad.Sci.U.S.A_111_E3825 |
| PubMedID: 25157130 |