| Title : Combining beta(2)-AR agonism with butyrylcholinesterase inhibition, a synergistic neuroprotective action against Alzheimer's disease - Wang_2026_RSC.Med.Chem__ |
| Author(s) : Wang A , Curel T , Claeysen S , Travers-Lesage V , Cadot M , Davis A , Sopkova-de Oliveira Santos J , Modeste F , Brazzolotto X , Nachon F , Dallemagne P , Since M , Rochais C |
| Ref : RSC Med Chem , : , 2026 |
| Abstract : |
| PubMedSearch : Wang_2026_RSC.Med.Chem__ |
| PubMedID: 42416270 |
| Gene_locus related to this paper: human-BCHE |
| Title : Rational Design and Evaluation of Rivastigmine-Based Pleiotropic Prodrugs for the Treatment of Alzheimer's Disease - Travers-Lesage_2026_ACS.Chem.Neurosci__ |
| Author(s) : Travers-Lesage V , Since M , Wang A , Davis A , Fayolle D , Bernay B , Modeste F , Nachon F , Brazzalotto X , Crouzier L , Sopkova-de Oliveira Santos J , Maurice T , Dallemagne P , Rochais C |
| Ref : ACS Chem Neurosci , : , 2026 |
| Abstract : |
| PubMedSearch : Travers-Lesage_2026_ACS.Chem.Neurosci__ |
| PubMedID: 41972598 |
| Title : Design, synthesis and preliminary biological evaluation of rivastigmine-INDY hybrids as multitarget ligands against Alzheimer's disease by targeting butyrylcholinesterase and DYRK1A\/CLK1 kinases - Tintas_2024_RSC.Med.Chem_15_963 |
| Author(s) : Tintas ML , Peauger L , Barre A , Papamical C , Besson T , Sopkova-de Oliveira Santos J , Gembus V , Levacher V |
| Ref : RSC Med Chem , 15 :963 , 2024 |
| Abstract : |
| PubMedSearch : Tintas_2024_RSC.Med.Chem_15_963 |
| PubMedID: 38516603 |
| Title : Development of Novel Potential Pleiotropic Compounds of Interest in Alzheimer's Disease Treatment through Rigidification Strategy - Lecoutey_2021_Molecules_26_ |
| Author(s) : Lecoutey C , Legay R , Davis A , Sopkova-de Oliveira Santos J , Dallemagne P , Rochais C |
| Ref : Molecules , 26 : , 2021 |
| Abstract : |
| PubMedSearch : Lecoutey_2021_Molecules_26_ |
| PubMedID: 33926141 |
| Title : Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT(6) receptor antagonist with therapeutic interest in Alzheimer's disease - Toublet_2021_Eur.J.Med.Chem_210_113059 |
| Author(s) : Toublet FX , Lalut J , Hatat B , Lecoutey C , Davis A , Since M , Corvaisier S , Freret T , Sopkova-de Oliveira Santos J , Claeysen S , Boulouard M , Dallemagne P , Rochais C |
| Ref : Eur Journal of Medicinal Chemistry , 210 :113059 , 2021 |
| Abstract : |
| PubMedSearch : Toublet_2021_Eur.J.Med.Chem_210_113059 |
| PubMedID: 33310288 |
| Title : Rational design of novel benzisoxazole derivatives with acetylcholinesterase inhibitory and serotoninergic 5-HT4 receptors activities for the treatment of Alzheimer's disease - Lalut_2020_Sci.Rep_10_3014 |
| Author(s) : Lalut J , Payan H , Davis A , Lecoutey C , Legay R , Sopkova-de Oliveira Santos J , Claeysen S , Dallemagne P , Rochais C |
| Ref : Sci Rep , 10 :3014 , 2020 |
| Abstract : |
| PubMedSearch : Lalut_2020_Sci.Rep_10_3014 |
| PubMedID: 32080261 |
| Title : In silico chemical library screening and experimental validation of novel compounds with potential varroacide activities - Riva_2019_Pestic.Biochem.Physiol_160_11 |
| Author(s) : Riva C , Suzanne P , Charpentier G , Dulin F , Halm-Lemeille MP , Sopkova-de Oliveira Santos J |
| Ref : Pestic Biochem Physiol , 160 :11 , 2019 |
| Abstract : |
| PubMedSearch : Riva_2019_Pestic.Biochem.Physiol_160_11 |
| PubMedID: 31519244 |
| Title : Benzylphenylpyrrolizinones with Anti-amyloid and Radical Scavenging Effects, Potentially Useful in Alzheimer's Disease Treatment - Jourdan_2017_ChemMedChem_12_913 |
| Author(s) : Jourdan JP , Since M , El Kihel L , Lecoutey C , Corvaisier S , Legay R , Sopkova-de Oliveira Santos J , Cresteil T , Malzert-Freon A , Rochais C , Dallemagne P |
| Ref : ChemMedChem , 12 :913 , 2017 |
| Abstract : |
| PubMedSearch : Jourdan_2017_ChemMedChem_12_913 |
| PubMedID: 28342294 |
| Title : Donepezil-Based Central Acetylcholinesterase Inhibitors by Means of a Bio-Oxidizable Prodrug Strategy: Design, Synthesis, and in Vitro Biological Evaluation - Peauger_2017_J.Med.Chem_60_5909 |
| Author(s) : Peauger L , Azzouz R , Gembus V , Tintas ML , Sopkova-de Oliveira Santos J , Bohn P , Papamicael C , Levacher V |
| Ref : Journal of Medicinal Chemistry , 60 :5909 , 2017 |
| Abstract : |
| PubMedSearch : Peauger_2017_J.Med.Chem_60_5909 |
| PubMedID: 28613859 |
| Title : Novel benzylidenephenylpyrrolizinones with pleiotropic activities potentially useful in Alzheimer's disease treatment - Jourdan_2016_Eur.J.Med.Chem_114_365 |
| Author(s) : Jourdan JP , Since M , El Kihel L , Lecoutey C , Corvaisier S , Legay R , Sopkova-de Oliveira Santos J , Cresteil T , Malzert-Freon A , Rochais C , Dallemagne P |
| Ref : Eur Journal of Medicinal Chemistry , 114 :365 , 2016 |
| Abstract : |
| PubMedSearch : Jourdan_2016_Eur.J.Med.Chem_114_365 |
| PubMedID: 27046230 |
| Title : Virtual screening discovery of new acetylcholinesterase inhibitors issued from CERMN chemical library - Sopkova-de_2010_J.Chem.Inf.Model_50_422 |
| Author(s) : Sopkova-de Oliveira Santos J , Lesnard A , Agondanou JH , Dupont N , Godard AM , Stiebing S , Rochais C , Fabis F , Dallemagne P , Bureau R , Rault S |
| Ref : J Chem Inf Model , 50 :422 , 2010 |
| Abstract : |
| PubMedSearch : Sopkova-de_2010_J.Chem.Inf.Model_50_422 |
| PubMedID: 20196555 |