| Title : Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT(4) receptors with potential interest in the treatment of Alzheimer's disease - Rochais_2024_Eur.J.Med.Chem_280_116975 |
| Author(s) : Rochais C , Lecoutey C , Lalut J , Davis A , Duval E , Gaven F , Largilliere S , Nee G , Corvaisier S , Sopkova de Oliveira Santos J , Since M , Freret T , Legrand R , Callizot N , Claeysen S , Boulouard M , Dallemagne P |
| Ref : Eur Journal of Medicinal Chemistry , 280 :116975 , 2024 |
| Abstract : |
| PubMedSearch : Rochais_2024_Eur.J.Med.Chem_280_116975 |
| PubMedID: 39454222 |
| Title : First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease - Guieu_2020_Molecules_26_ |
| Author(s) : Guieu B , Lecoutey C , Legay R , Davis A , Sopkova de Oliveira Santos J , Altomare CD , Catto M , Rochais C , Dallemagne P |
| Ref : Molecules , 26 : , 2020 |
| Abstract : |
| PubMedSearch : Guieu_2020_Molecules_26_ |
| PubMedID: 33375412 |
| Title : Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease - Toublet_2019_Molecules_24_ |
| Author(s) : Toublet FX , Lecoutey C , Lalut J , Hatat B , Davis A , Since M , Corvaisier S , Freret T , Sopkova de Oliveira Santos J , Claeysen S , Boulouard M , Dallemagne P , Rochais C |
| Ref : Molecules , 24 : , 2019 |
| Abstract : |
| PubMedSearch : Toublet_2019_Molecules_24_ |
| PubMedID: 31370232 |
| Title : Novel multitarget-directed ligands (MTDLs) with acetylcholinesterase (AChE) inhibitory and serotonergic subtype 4 receptor (5-HT4R) agonist activities as potential agents against Alzheimer's disease: the design of donecopride - Rochais_2015_J.Med.Chem_58_3172 |
| Author(s) : Rochais C , Lecoutey C , Gaven F , Giannoni P , Hamidouche K , Hedou D , Dubost E , Genest D , Yahiaoui S , Freret T , Bouet V , Dauphin F , Sopkova de Oliveira Santos J , Ballandonne C , Corvaisier S , Malzert-Freon A , Legay R , Boulouard M , Claeysen S , Dallemagne P |
| Ref : Journal of Medicinal Chemistry , 58 :3172 , 2015 |
| Abstract : |
| PubMedSearch : Rochais_2015_J.Med.Chem_58_3172 |
| PubMedID: 25793650 |