| Title : Design of potent dipeptidyl peptidase IV (DPP-4) inhibitors by employing a strategy to form a salt bridge with Lys554 - Maezaki_2017_Bioorg.Med.Chem.Lett_27_3565 |
| Author(s) : Maezaki H , Tawada M , Yamashita T , Banno Y , Miyamoto Y , Yamamoto Y , Ikedo K , Kosaka T , Tsubotani S , Tani A , Asakawa T , Suzuki N , Oi S |
| Ref : Bioorganic & Medicinal Chemistry Lett , 27 :3565 , 2017 |
| Abstract : |
| PubMedSearch : Maezaki_2017_Bioorg.Med.Chem.Lett_27_3565 |
| PubMedID: 28579121 |
| Title : Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism - Grimshaw_2016_PLoS.One_11_e0157509 |
| Author(s) : Grimshaw CE , Jennings A , Kamran R , Ueno H , Nishigaki N , Kosaka T , Tani A , Sano H , Kinugawa Y , Koumura E , Shi L , Takeuchi K |
| Ref : PLoS ONE , 11 :e0157509 , 2016 |
| Abstract : |
| PubMedSearch : Grimshaw_2016_PLoS.One_11_e0157509 |
| PubMedID: 27328054 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor - Miyamoto_2011_J.Med.Chem_54_831 |
| Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Yashiro H , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Sasaki M , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Journal of Medicinal Chemistry , 54 :831 , 2011 |
| Abstract : |
| PubMedSearch : Miyamoto_2011_J.Med.Chem_54_831 |
| PubMedID: 21218817 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125 - Miyamoto_2011_Bioorg.Med.Chem_19_172 |
| Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Bioorganic & Medicinal Chemistry , 19 :172 , 2011 |
| Abstract : |
| PubMedSearch : Miyamoto_2011_Bioorg.Med.Chem_19_172 |
| PubMedID: 21163664 |
| Title : Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554 - Banno_2011_Bioorg.Med.Chem_19_4953 |
| Author(s) : Banno Y , Miyamoto Y , Sasaki M , Oi S , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Tawada M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4953 , 2011 |
| Abstract : |
| PubMedSearch : Banno_2011_Bioorg.Med.Chem_19_4953 |
| PubMedID: 21764322 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554 - Maezaki_2011_Bioorg.Med.Chem_19_4482 |
| Author(s) : Maezaki H , Banno Y , Miyamoto Y , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Sasaki M , Tsubotani S , Tani A , Funami M , Yamamoto Y , Tawada M , Aertgeerts K , Yano J , Oi S |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4482 , 2011 |
| Abstract : |
| PubMedSearch : Maezaki_2011_Bioorg.Med.Chem_19_4482 |
| PubMedID: 21741847 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Biochemical and molecular characterization of a periplasmic hydrolase for oxidized polyvinyl alcohol from Sphingomonas sp. strain 113P3 - Klomklang_2005_Microbiology_151_1255 |
| Author(s) : Klomklang W , Tani A , Kimbara K , Mamoto R , Ueda T , Shimao M , Kawai F |
| Ref : Microbiology , 151 :1255 , 2005 |
| Abstract : |
| PubMedSearch : Klomklang_2005_Microbiology_151_1255 |
| PubMedID: 15817792 |
| Gene_locus related to this paper: sphs1-OPH |