| Title : Design of potent dipeptidyl peptidase IV (DPP-4) inhibitors by employing a strategy to form a salt bridge with Lys554 - Maezaki_2017_Bioorg.Med.Chem.Lett_27_3565 |
| Author(s) : Maezaki H , Tawada M , Yamashita T , Banno Y , Miyamoto Y , Yamamoto Y , Ikedo K , Kosaka T , Tsubotani S , Tani A , Asakawa T , Suzuki N , Oi S |
| Ref : Bioorganic & Medicinal Chemistry Lett , 27 :3565 , 2017 |
| Abstract : |
| PubMedSearch : Maezaki_2017_Bioorg.Med.Chem.Lett_27_3565 |
| PubMedID: 28579121 |
| Title : Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism - Grimshaw_2016_PLoS.One_11_e0157509 |
| Author(s) : Grimshaw CE , Jennings A , Kamran R , Ueno H , Nishigaki N , Kosaka T , Tani A , Sano H , Kinugawa Y , Koumura E , Shi L , Takeuchi K |
| Ref : PLoS ONE , 11 :e0157509 , 2016 |
| Abstract : |
| PubMedSearch : Grimshaw_2016_PLoS.One_11_e0157509 |
| PubMedID: 27328054 |
| Gene_locus related to this paper: human-DPP4 |
| Title : [Clinical Analysis of Esophageal Bypass Surgery with Nutritional Assessment in Patients with Unresectable Esophageal Cancer] - Funaki_2015_Gan.To.Kagaku.Ryoho_42_1543 |
| Author(s) : Funaki H , Fujii Y , Fujita J , Morioka E , Kaida D , Ohonishi T , Tomita Y , Noguchi M , Fujita H , Kinami S , Nakano Y , Ueda N , Kosaka T |
| Ref : Japanese Journal of Cancer & Chemotherapy , 42 :1543 , 2015 |
| Abstract : |
| PubMedSearch : Funaki_2015_Gan.To.Kagaku.Ryoho_42_1543 |
| PubMedID: 26805090 |
| Title : Genetic basis of the highly efficient yeast Kluyveromyces marxianus: complete genome sequence and transcriptome analyses - Lertwattanasakul_2015_Biotechnol.Biofuels_8_47 |
| Author(s) : Lertwattanasakul N , Kosaka T , Hosoyama A , Suzuki Y , Rodrussamee N , Matsutani M , Murata M , Fujimoto N , Suprayogi , Tsuchikane K , Limtong S , Fujita N , Yamada M |
| Ref : Biotechnol Biofuels , 8 :47 , 2015 |
| Abstract : |
| PubMedSearch : Lertwattanasakul_2015_Biotechnol.Biofuels_8_47 |
| PubMedID: 25834639 |
| Gene_locus related to this paper: klumd-w0tha9 |
| Title : Complete Genome Sequence of a Thermophilic Hydrogenotrophic Methanogen, Methanothermobacter sp. Strain CaT2 - Kosaka_2013_Genome.Announc_1_ |
| Author(s) : Kosaka T , Toh H , Toyoda A |
| Ref : Genome Announc , 1 : , 2013 |
| Abstract : |
| PubMedSearch : Kosaka_2013_Genome.Announc_1_ |
| PubMedID: 23990577 |
| Gene_locus related to this paper: 9eury-t2gj08 |
| Title : Identification of 3-aminomethyl-1,2-dihydro-4-phenyl-1-isoquinolones: a new class of potent, selective, and orally active non-peptide dipeptidyl peptidase IV inhibitors that form a unique interaction with Lys554 - Banno_2011_Bioorg.Med.Chem_19_4953 |
| Author(s) : Banno Y , Miyamoto Y , Sasaki M , Oi S , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Tawada M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4953 , 2011 |
| Abstract : |
| PubMedSearch : Banno_2011_Bioorg.Med.Chem_19_4953 |
| PubMedID: 21764322 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Discovery of potent, selective, and orally bioavailable quinoline-based dipeptidyl peptidase IV inhibitors targeting Lys554 - Maezaki_2011_Bioorg.Med.Chem_19_4482 |
| Author(s) : Maezaki H , Banno Y , Miyamoto Y , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Sasaki M , Tsubotani S , Tani A , Funami M , Yamamoto Y , Tawada M , Aertgeerts K , Yano J , Oi S |
| Ref : Bioorganic & Medicinal Chemistry , 19 :4482 , 2011 |
| Abstract : |
| PubMedSearch : Maezaki_2011_Bioorg.Med.Chem_19_4482 |
| PubMedID: 21741847 |
| Gene_locus related to this paper: human-DPP4 |
| Title : Design and synthesis of 3-pyridylacetamide derivatives as dipeptidyl peptidase IV (DPP-4) inhibitors targeting a bidentate interaction with Arg125 - Miyamoto_2011_Bioorg.Med.Chem_19_172 |
| Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Bioorganic & Medicinal Chemistry , 19 :172 , 2011 |
| Abstract : |
| PubMedSearch : Miyamoto_2011_Bioorg.Med.Chem_19_172 |
| PubMedID: 21163664 |
| Title : Discovery of a 3-pyridylacetic acid derivative (TAK-100) as a potent, selective and orally active dipeptidyl peptidase IV (DPP-4) inhibitor - Miyamoto_2011_J.Med.Chem_54_831 |
| Author(s) : Miyamoto Y , Banno Y , Yamashita T , Fujimoto T , Oi S , Moritoh Y , Asakawa T , Kataoka O , Yashiro H , Takeuchi K , Suzuki N , Ikedo K , Kosaka T , Tsubotani S , Tani A , Sasaki M , Funami M , Amano M , Yamamoto Y , Aertgeerts K , Yano J , Maezaki H |
| Ref : Journal of Medicinal Chemistry , 54 :831 , 2011 |
| Abstract : |
| PubMedSearch : Miyamoto_2011_J.Med.Chem_54_831 |
| PubMedID: 21218817 |
| Gene_locus related to this paper: human-DPP4 |
| Title : The genome of Pelotomaculum thermopropionicum reveals niche-associated evolution in anaerobic microbiota - Kosaka_2008_Genome.Res_18_442 |
| Author(s) : Kosaka T , Kato S , Shimoyama T , Ishii S , Abe T , Watanabe K |
| Ref : Genome Res , 18 :442 , 2008 |
| Abstract : |
| PubMedSearch : Kosaka_2008_Genome.Res_18_442 |
| PubMedID: 18218977 |
| Gene_locus related to this paper: pelts-a5d5p1 |
| Title : Reconstruction and regulation of the central catabolic pathway in the thermophilic propionate-oxidizing syntroph Pelotomaculum thermopropionicum - Kosaka_2006_J.Bacteriol_188_202 |
| Author(s) : Kosaka T , Uchiyama T , Ishii S , Enoki M , Imachi H , Kamagata Y , Ohashi A , Harada H , Ikenaga H , Watanabe K |
| Ref : Journal of Bacteriology , 188 :202 , 2006 |
| Abstract : |
| PubMedSearch : Kosaka_2006_J.Bacteriol_188_202 |
| PubMedID: 16352836 |
| Gene_locus related to this paper: pelts-a5czq3 |
| Title : Investigation of the relationship between atherosclerosis and paraoxonase or homocysteine thiolactonase activity in patients with type 2 diabetes mellitus using a commercially available assay - Kosaka_2005_Clin.Chim.Acta_359_156 |
| Author(s) : Kosaka T , Yamaguchi M , Motomura T , Mizuno K |
| Ref : Clinica Chimica Acta , 359 :156 , 2005 |
| Abstract : |
| PubMedSearch : Kosaka_2005_Clin.Chim.Acta_359_156 |
| PubMedID: 15927175 |
| Title : Distribution of the calcium binding proteins, calbindin D-28K and parvalbumin, in the subicular complex of the adult mouse - Fujise_1995_Neurosci.Research_22_89 |
| Author(s) : Fujise N , Hunziker W , Heizmann CW , Kosaka T |
| Ref : Neuroscience Research , 22 :89 , 1995 |
| Abstract : |
| PubMedSearch : Fujise_1995_Neurosci.Research_22_89 |
| PubMedID: 7792085 |
| Title : Variations of collateral branching in the motor nerve fibers in the skeletal muscle of adult rats - Kawabuchi_1993_Acta.Histochem_94_173 |
| Author(s) : Kawabuchi M , Kosaka T |
| Ref : Acta Histochemica , 94 :173 , 1993 |
| Abstract : |
| PubMedSearch : Kawabuchi_1993_Acta.Histochem_94_173 |
| PubMedID: 8351978 |