Title : 2-(Alkylthio)pyrimidin-4-ones as novel, reversible inhibitors of lipoprotein-associated phospholipase A2 - Boyd_2000_Bioorg.Med.Chem.Lett_10_395 |
Author(s) : Boyd HF , Flynn ST , Hickey DM , Ife RJ , Jones M , Leach CA , Macphee CH , Milliner KJ , Rawlings DA , Slingsby BP , Smith SA , Stansfield IG , Tew DG , Theobald CJ |
Ref : Bioorganic & Medicinal Chemistry Lett , 10 :395 , 2000 |
Abstract : |
PubMedSearch : Boyd_2000_Bioorg.Med.Chem.Lett_10_395 |
PubMedID: 10714508 |
Title : Lipoprotein-associated phospholipase A2, platelet-activating factor acetylhydrolase, generates two bioactive products during the oxidation of low-density lipoprotein: use of a novel inhibitor - MacPhee_1999_Biochem.J_338 ( Pt 2)_479 |
Author(s) : Macphee CH , Moores KE , Boyd HF , Dhanak D , Ife RJ , Leach CA , Leake DS , Milliner KJ , Patterson RA , Suckling KE , Tew DG , Hickey DM |
Ref : Biochemical Journal , 338 ( Pt 2) :479 , 1999 |
Abstract : |
PubMedSearch : MacPhee_1999_Biochem.J_338 ( Pt 2)_479 |
PubMedID: 10024526 |
Title : Expression, purification and characterization of a human serine-dependent phospholipase A2 with high specificity for oxidized phospholipids and platelet activating factor - Rice_1998_Biochem.J_330 ( Pt 3)_1309 |
Author(s) : Rice SQ , Southan C , Boyd HF , Terrett JA , Macphee CH , Moores K , Gloger IS , Tew DG |
Ref : Biochemical Journal , 330 ( Pt 3) :1309 , 1998 |
Abstract : |
PubMedSearch : Rice_1998_Biochem.J_330 ( Pt 3)_1309 |
PubMedID: 9494101 |
Gene_locus related to this paper: human-PAFAH2 |
Title : Mechanism of inhibition of LDL phospholipase A2 by monocyclic-beta-lactams. Burst kinetics and the effect of stereochemistry - Tew_1998_Biochemistry_37_10087 |
Author(s) : Tew DG , Boyd HF , Ashman S , Theobald C , Leach CA |
Ref : Biochemistry , 37 :10087 , 1998 |
Abstract : |
PubMedSearch : Tew_1998_Biochemistry_37_10087 |
PubMedID: 9665713 |
Title : Purification, properties, sequencing, and cloning of a lipoprotein-associated, serine-dependent phospholipase involved in the oxidative modification of low-density lipoproteins - Tew_1996_Arterioscler.Thromb.Vasc.Biol_16_591 |
Author(s) : Tew DG , Southan C , Rice SQ , Lawrence MP , Li H , Boyd HF , Moores K , Gloger IS , Macphee CH |
Ref : Arterioscler Thromb Vasc Biol , 16 :591 , 1996 |
Abstract : |
PubMedSearch : Tew_1996_Arterioscler.Thromb.Vasc.Biol_16_591 |
PubMedID: 8624782 |
Gene_locus related to this paper: human-PLA2G7 |