| Title : The discovery of azetidine-piperazine di-amides as potent, selective and reversible monoacylglycerol lipase (MAGL) inhibitors - Zhu_2020_Bioorg.Med.Chem.Lett_30_127243 |
| Author(s) : Zhu B , Connolly PJ , Zhang YM , McDonnell ME , Bian H , Lin SC , Liu L , Zhang SP , Chevalier KM , Brandt MR , Milligan CM , Flores CM , Macielag MJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 30 :127243 , 2020 |
| Abstract : |
| PubMedSearch : Zhu_2020_Bioorg.Med.Chem.Lett_30_127243 |
| PubMedID: 32527545 |
| Gene_locus related to this paper: human-MGLL |
| Title : Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor - Wyatt_2020_J.Pharmacol.Exp.Ther_372_339 |
| Author(s) : Wyatt RM , Fraser I , Welty N , Lord B , Wennerholm M , Sutton S , Ameriks MK , Dugovic C , Yun S , White A , Nguyen L , Koudriakova T , Tian G , Suarez J , Szewczuk L , Bonnette W , Ahn K , Ghosh B , Flores CM , Connolly PJ , Zhu B , Macielag MJ , Brandt MR , Chevalier K , Zhang SP , Lovenberg T , Bonaventure P |
| Ref : Journal of Pharmacology & Experimental Therapeutics , 372 :339 , 2020 |
| Abstract : |
| PubMedSearch : Wyatt_2020_J.Pharmacol.Exp.Ther_372_339 |
| PubMedID: 31818916 |
| Title : The discovery of diazetidinyl diamides as potent and reversible inhibitors of monoacylglycerol lipase (MAGL) - Zhu_2020_Bioorg.Med.Chem.Lett_30_127198 |
| Author(s) : Zhu B , Connolly PJ , Zhang SP , Chevalier KM , Milligan CM , Flores CM , Macielag MJ |
| Ref : Bioorganic & Medicinal Chemistry Lett , 30 :127198 , 2020 |
| Abstract : |
| PubMedSearch : Zhu_2020_Bioorg.Med.Chem.Lett_30_127198 |
| PubMedID: 32334914 |
| Title : Screening and characterization of human monoglyceride lipase active site inhibitors using orthogonal binding and functional assays - Clemente_2012_J.Biomol.Screen_17_629 |
| Author(s) : Clemente JC , Nulton E , Nelen M , Todd MJ , Maguire D , Schalk-Hihi C , Kuo LC , Zhang SP , Flores CM , Kranz JK |
| Ref : J Biomol Screen , 17 :629 , 2012 |
| Abstract : |
| PubMedSearch : Clemente_2012_J.Biomol.Screen_17_629 |
| PubMedID: 22496098 |
| Title : Cloning, expression and characterization of a lipase gene from the Candida antarctica ZJB09193 and its application in biosynthesis of vitamin A esters - Liu_2012_Microbiol.Res_167_452 |
| Author(s) : Liu ZQ , Zheng XB , Zhang SP , Zheng YG |
| Ref : Microbiol Res , 167 :452 , 2012 |
| Abstract : |
| PubMedSearch : Liu_2012_Microbiol.Res_167_452 |
| PubMedID: 22281522 |