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Title : FASN inhibition targets multiple drivers of NASH by reducing steatosis, inflammation and fibrosis in preclinical models - O'Farrell_2022_Sci.Rep_12_15661 |
Author(s) : O'Farrell M , Duke G , Crowley R , Buckley D , Martins EB , Bhattacharya D , Friedman SL , Kemble G |
Ref : Sci Rep , 12 :15661 , 2022 |
Abstract : O'Farrell_2022_Sci.Rep_12_15661 |
ESTHER : O'Farrell_2022_Sci.Rep_12_15661 |
PubMedSearch : O'Farrell_2022_Sci.Rep_12_15661 |
PubMedID: 36123383 |
Title : FASN Inhibition and Taxane Treatment Combine to Enhance Anti-tumor Efficacy in Diverse Xenograft Tumor Models through Disruption of Tubulin Palmitoylation and Microtubule Organization and FASN Inhibition-Mediated Effects on Oncogenic Signaling and Gene Expression - Heuer_2017_EBioMedicine_16_51 |
Author(s) : Heuer TS , Ventura R , Mordec K , Lai J , Fridlib M , Buckley D , Kemble G |
Ref : EBioMedicine , 16 :51 , 2017 |
Abstract : Heuer_2017_EBioMedicine_16_51 |
ESTHER : Heuer_2017_EBioMedicine_16_51 |
PubMedSearch : Heuer_2017_EBioMedicine_16_51 |
PubMedID: 28159572 |
Title : Inhibition of de novo Palmitate Synthesis by Fatty Acid Synthase Induces Apoptosis in Tumor Cells by Remodeling Cell Membranes, Inhibiting Signaling Pathways, and Reprogramming Gene Expression - Ventura_2015_EBioMedicine_2_808 |
Author(s) : Ventura R , Mordec K , Waszczuk J , Wang Z , Lai J , Fridlib M , Buckley D , Kemble G , Heuer TS |
Ref : EBioMedicine , 2 :808 , 2015 |
Abstract : Ventura_2015_EBioMedicine_2_808 |
ESTHER : Ventura_2015_EBioMedicine_2_808 |
PubMedSearch : Ventura_2015_EBioMedicine_2_808 |
PubMedID: 26425687 |
Title : Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains - Rohmer_2007_Genome.Biol_8_R102 |
Author(s) : Rohmer L , Fong C , Abmayr S , Wasnick M , Larson Freeman TJ , Radey M , Guina T , Svensson K , Hayden HS , Jacobs M , Gallagher LA , Manoil C , Ernst RK , Drees B , Buckley D , Haugen E , Bovee D , Zhou Y , Chang J , Levy R , Lim R , Gillett W , Guenthener D , Kang A , Shaffer SA , Taylor G , Chen J , Gallis B , D'Argenio DA , Forsman M , Olson MV , Goodlett DR , Kaul R , Miller SI , Brittnacher MJ |
Ref : Genome Biol , 8 :R102 , 2007 |
Abstract : Rohmer_2007_Genome.Biol_8_R102 |
ESTHER : Rohmer_2007_Genome.Biol_8_R102 |
PubMedSearch : Rohmer_2007_Genome.Biol_8_R102 |
PubMedID: 17550600 |
Gene_locus related to this paper: fratn-a0q8l8 , fratt-q5ngu5 |