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Title : Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia - Chan_2008_Proc.Natl.Acad.Sci.U.S.A_105_10978 |
Author(s) : Chan WY , McKinzie DL , Bose S , Mitchell SN , Witkin JM , Thompson RC , Christopoulos A , Lazareno S , Birdsall NJ , Bymaster FP , Felder CC |
Ref : Proc Natl Acad Sci U S A , 105 :10978 , 2008 |
Abstract : Chan_2008_Proc.Natl.Acad.Sci.U.S.A_105_10978 |
ESTHER : Chan_2008_Proc.Natl.Acad.Sci.U.S.A_105_10978 |
PubMedSearch : Chan_2008_Proc.Natl.Acad.Sci.U.S.A_105_10978 |
PubMedID: 18678919 |
Title : Progress toward a high-affinity allosteric enhancer at muscarinic M1 receptors - Lazareno_2003_J.Mol.Neurosci_20_363 |
Author(s) : Lazareno S , Popham A , Birdsall NJ |
Ref : Journal of Molecular Neuroscience , 20 :363 , 2003 |
Abstract : Lazareno_2003_J.Mol.Neurosci_20_363 |
ESTHER : Lazareno_2003_J.Mol.Neurosci_20_363 |
PubMedSearch : Lazareno_2003_J.Mol.Neurosci_20_363 |
PubMedID: 14501021 |
Title : Interactions of orthosteric and allosteric ligands with [3H]dimethyl-W84 at the common allosteric site of muscarinic M2 receptors - Trankle_2003_Mol.Pharmacol_64_180 |
Author(s) : Trankle C , Weyand O , Voigtlander U , Mynett A , Lazareno S , Birdsall NJ , Mohr K |
Ref : Molecular Pharmacology , 64 :180 , 2003 |
Abstract : Trankle_2003_Mol.Pharmacol_64_180 |
ESTHER : Trankle_2003_Mol.Pharmacol_64_180 |
PubMedSearch : Trankle_2003_Mol.Pharmacol_64_180 |
PubMedID: 12815174 |
Title : Towards a high-affinity allosteric enhancer at muscarinic M1 receptors - Lazareno_2002_J.Mol.Neurosci_19_123 |
Author(s) : Lazareno S , Popham A , Birdsall NJ |
Ref : Journal of Molecular Neuroscience , 19 :123 , 2002 |
Abstract : Lazareno_2002_J.Mol.Neurosci_19_123 |
ESTHER : Lazareno_2002_J.Mol.Neurosci_19_123 |
PubMedSearch : Lazareno_2002_J.Mol.Neurosci_19_123 |
PubMedID: 12212769 |
Title : Multiple allosteric sites on muscarinic receptors - Birdsall_2001_Life.Sci_68(22-23)_2517 |
Author(s) : Birdsall NJ , Lazareno S , Popham A , Saldanha J |
Ref : Life Sciences , 68 :2517 , 2001 |
Abstract : Birdsall_2001_Life.Sci_68(22-23)_2517 |
ESTHER : Birdsall_2001_Life.Sci_68(22-23)_2517 |
PubMedSearch : Birdsall_2001_Life.Sci_68(22-23)_2517 |
PubMedID: 11392621 |
Title : Poster: Binding of the radiolabelled allosteric ligand [3H]dimethyl-W84 to M4 muscarinic receptors - |
Author(s) : Trankle C , Weyand O , Lazareno S , Birdsall NJ , Mohr K |
Ref : Life Sciences , 68 :2619 , 2001 |
PubMedID: |
Title : Poster: Effects of atypical allosteric agents on the binding of [3H]dimethyl-w84 to M2 receptors - |
Author(s) : Weyand O , Lazareno S , Birdsall NJ , Mohr K , Trankle C |
Ref : Life Sciences , 68 :2621 , 2001 |
PubMedID: |
Title : Allosteric effects of four stereoisomers of a fused indole ring system with 3H-N-methylscopolamine and acetylcholine at M1-M4 muscarinic receptors - Lazareno_1999_Life.Sci_64(6-7)_519 |
Author(s) : Lazareno S , Birdsall B , Fukazawa T , Gharagozloo P , Hashimoto T , Kuwano H , Popham A , Sugimoto M , Birdsall NJ |
Ref : Life Sciences , 64 :519 , 1999 |
Abstract : Lazareno_1999_Life.Sci_64(6-7)_519 |
ESTHER : Lazareno_1999_Life.Sci_64(6-7)_519 |
PubMedSearch : Lazareno_1999_Life.Sci_64(6-7)_519 |
PubMedID: 10069518 |
Title : Poster: Synthesis of novel pentacyclic carbazoles as muscarinic allosteric agents - |
Author(s) : Gharagozloo P , Lazareno S , Miyauchi M , Popham A , Birdsall NJ |
Ref : Life Sciences , 60 :1169 , 1997 |
PubMedID: |
Title : Poster: Allosteric actions of brucine analogs at muscarinic receptor subtypes - |
Author(s) : Lazareno S , Farries T , Gharagozloo P , Kuonen D , Popham A , Sugimoto M , Birdsall NJ |
Ref : Life Sciences , 60 :1169 , 1997 |
PubMedID: |
Title : Selective allosteric enhancement of the binding and actions of acetylcholine at muscarinic receptor subtypes - Birdsall_1997_Life.Sci_60(13-14)_1047 |
Author(s) : Birdsall NJ , Farries T , Gharagozloo P , Kobayashi S , Kuonen D , Lazareno S , Popham A , Sugimoto M |
Ref : Life Sciences , 60 :1047 , 1997 |
Abstract : Birdsall_1997_Life.Sci_60(13-14)_1047 |
ESTHER : Birdsall_1997_Life.Sci_60(13-14)_1047 |
PubMedSearch : Birdsall_1997_Life.Sci_60(13-14)_1047 |
PubMedID: 9121346 |
Title : Stereoselective recognition of the enantiomers of phenglutarimide and of six related compounds by four muscarinic receptor subtypes - Waelbroeck_1996_Br.J.Pharmacol_119_1319 |
Author(s) : Waelbroeck M , Lazareno S , Pfaff O , Friebe T , Tastenoy M , Mutschler E , Lambrecht G |
Ref : British Journal of Pharmacology , 119 :1319 , 1996 |
Abstract : Waelbroeck_1996_Br.J.Pharmacol_119_1319 |
ESTHER : Waelbroeck_1996_Br.J.Pharmacol_119_1319 |
PubMedSearch : Waelbroeck_1996_Br.J.Pharmacol_119_1319 |
PubMedID: 8968538 |
Title : Allosteric regulation of muscarinic receptors - |
Author(s) : Birdsall NJ , Lazareno S , Matsui H |
Ref : Prog Brain Res , 109 :147 , 1996 |
PubMedID: 9009701 |
Title : Poster: Application of site-directed mutagenesis to the location of the gallamine binding site on muscarinic receptors - |
Author(s) : Matsui H , Lazareno S , Birdsall NJ |
Ref : Life Sciences , 56(11-12) :1011 , 1995 |
PubMedID: |
Title : Pharmacological characterization of acetylcholine-stimulated [35S]-GTP gamma S binding mediated by human muscarinic m1-m4 receptors: antagonist studies - Lazareno_1993_Br.J.Pharmacol_109_1120 |
Author(s) : Lazareno S , Birdsall NJ |
Ref : British Journal of Pharmacology , 109 :1120 , 1993 |
Abstract : Lazareno_1993_Br.J.Pharmacol_109_1120 |
ESTHER : Lazareno_1993_Br.J.Pharmacol_109_1120 |
PubMedSearch : Lazareno_1993_Br.J.Pharmacol_109_1120 |
PubMedID: 8401923 |
Title : Pharmacological characterization of guanine nucleotide exchange reactions in membranes from CHO cells stably transfected with human muscarinic receptors m1-m4 - Lazareno_1993_Life.Sci_52(5-6)_449 |
Author(s) : Lazareno S , Farries T , Birdsall NJ |
Ref : Life Sciences , 52 :449 , 1993 |
Abstract : Lazareno_1993_Life.Sci_52(5-6)_449 |
ESTHER : Lazareno_1993_Life.Sci_52(5-6)_449 |
PubMedSearch : Lazareno_1993_Life.Sci_52(5-6)_449 |
PubMedID: 8441327 |
Title : Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells - Lazareno_1990_Mol.Pharmacol_38_805 |
Author(s) : Lazareno S , Buckley NJ , Roberts FF |
Ref : Molecular Pharmacology , 38 :805 , 1990 |
Abstract : Lazareno_1990_Mol.Pharmacol_38_805 |
ESTHER : Lazareno_1990_Mol.Pharmacol_38_805 |
PubMedSearch : Lazareno_1990_Mol.Pharmacol_38_805 |
PubMedID: 2250662 |
Title : Functional and binding studies with muscarinic M2-subtype selective antagonists - Lazareno_1989_Br.J.Pharmacol_98_309 |
Author(s) : Lazareno S , Roberts FF |
Ref : British Journal of Pharmacology , 98 :309 , 1989 |
Abstract : Lazareno_1989_Br.J.Pharmacol_98_309 |
ESTHER : Lazareno_1989_Br.J.Pharmacol_98_309 |
PubMedSearch : Lazareno_1989_Br.J.Pharmacol_98_309 |
PubMedID: 2804551 |
Title : Poster: Muscarinic binding sites in chicken heart and rabbit peripheral lung - |
Author(s) : Lazareno S , Roberts FF |
Ref : Trends in Pharmacological Sciences , Suppl :108 , 1989 |
PubMedID: |