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Title : Discovery and preclinical profile of teneligliptin (3-[(2S,4S)-4-[4-(3-methyl-1-phenyl-1H-pyrazol-5-yl)piperazin-1-yl]pyrrolidin-2-y lcarbonyl]thiazolidine): a highly potent, selective, long-lasting and orally active dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes - Yoshida_2012_Bioorg.Med.Chem_20_5705 |
Author(s) : Yoshida T , Akahoshi F , Sakashita H , Kitajima H , Nakamura M , Sonda S , Takeuchi M , Tanaka Y , Ueda N , Sekiguchi S , Ishige T , Shima K , Nabeno M , Abe Y , Anabuki J , Soejima A , Yoshida K , Takashina Y , Ishii S , Kiuchi S , Fukuda S , Tsutsumiuchi R , Kosaka K , Murozono T , Nakamaru Y , Utsumi H , Masutomi N , Kishida H , Miyaguchi I , Hayashi Y |
Ref : Bioorganic & Medicinal Chemistry , 20 :5705 , 2012 |
Abstract : Yoshida_2012_Bioorg.Med.Chem_20_5705 |
ESTHER : Yoshida_2012_Bioorg.Med.Chem_20_5705 |
PubMedSearch : Yoshida_2012_Bioorg.Med.Chem_20_5705 |
PubMedID: 22959556 |
Gene_locus related to this paper: human-DPP4 |