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| Title : 4-Amidophenol Quinone Methide Precursors: Effective and Broad-Scope Nonoxime Reactivators of Organophosphorus-Inhibited Cholinesterases and Resurrectors of Organophosphorus-Aged Acetylcholinesterase - Lovins_2024_ACS.Chem.Neurosci__ |
| Author(s) : Lovins AR , Miller KA , Buck AK , Ensey DS , Homoelle RK , Murtha MC , Ward NA , Shanahan LA , Gutti G , Shriwas P , McElroy CA , Callam CS , Hadad CM |
| Ref : ACS Chem Neurosci , : , 2024 |
| Abstract : Lovins_2024_ACS.Chem.Neurosci__ |
| ESTHER : Lovins_2024_ACS.Chem.Neurosci__ |
| PubMedSearch : Lovins_2024_ACS.Chem.Neurosci__ |
| PubMedID: 38621296 |
| Title : Treatment of Organophosphorus Poisoning with 6-Alkoxypyridin-3-ol Quinone Methide Precursors: Resurrection of Methylphosphonate-Aged Acetylcholinesterase - Clay_2024_Chem.Res.Toxicol__ |
| Author(s) : Clay WK , Buck AK , He Y , Hernandez Sanchez DN , Ward NA , Lear JM , Nguyen KQ , Clark BH , Sapia RJ , Lalisse RF , Sriraman A , Cadieux CL , McElroy CA , Callam CS , Hadad CM |
| Ref : Chemical Research in Toxicology , : , 2024 |
| Abstract : Clay_2024_Chem.Res.Toxicol__ |
| ESTHER : Clay_2024_Chem.Res.Toxicol__ |
| PubMedSearch : Clay_2024_Chem.Res.Toxicol__ |
| PubMedID: 38556765 |
| Title : Targeted Metabolomics of Organophosphate Pesticides and Chemical Warfare Nerve Agent Simulants Using High- and Low-Dose Exposure in Human Liver Microsomes - Agarwal_2023_Metabolites_13_ |
| Author(s) : Agarwal G , Tichenor H , Roo S , Lane TR , Ekins S , McElroy CA |
| Ref : Metabolites , 13 : , 2023 |
| Abstract : Agarwal_2023_Metabolites_13_ |
| ESTHER : Agarwal_2023_Metabolites_13_ |
| PubMedSearch : Agarwal_2023_Metabolites_13_ |
| PubMedID: 37110155 |
| Title : A Novel, Modified Human Butyrylcholinesterase Catalytically Degrades the Chemical Warfare Nerve Agent, Sarin - McGarry_2020_Toxicol.Sci_174_133 |
| Author(s) : McGarry KG , Lalisse RF , Moyer RA , Johnson KM , Tallan AM , Winters TP , Taris JE , McElroy CA , Lemmon EE , Shafaat HS , Fan Y , Deal A , Marguet SC , Harvilchuck JA , Hadad CM , Wood DW |
| Ref : Toxicol Sci , 174 :133 , 2020 |
| Abstract : McGarry_2020_Toxicol.Sci_174_133 |
| ESTHER : McGarry_2020_Toxicol.Sci_174_133 |
| PubMedSearch : McGarry_2020_Toxicol.Sci_174_133 |
| PubMedID: 31879758 |
| Title : Demonstration of In Vitro Resurrection of Aged Acetylcholinesterase after Exposure to Organophosphorus Chemical Nerve Agents - Zhuang_2018_J.Med.Chem_61_7034 |
| Author(s) : Zhuang Q , Franjesevic AJ , Corrigan TS , Coldren WH , Dicken R , Sillart S , DeYong A , Yoshino N , Smith J , Fabry S , Fitzpatrick K , Blanton TG , Joseph J , Yoder RJ , McElroy CA , Ekici OD , Callam CS , Hadad CM |
| Ref : Journal of Medicinal Chemistry , 61 :7034 , 2018 |
| Abstract : Zhuang_2018_J.Med.Chem_61_7034 |
| ESTHER : Zhuang_2018_J.Med.Chem_61_7034 |
| PubMedSearch : Zhuang_2018_J.Med.Chem_61_7034 |
| PubMedID: 29870665 |
| Title : Study of para-Quinone Methide Precursors toward the Realkylation of Aged Acetylcholinesterase - Yoder_2017_ACS.Med.Chem.Lett_8_622 |
| Author(s) : Yoder RJ , Zhuang Q , Beck JM , Franjesevic AJ , Blanton TG , Sillart S , Secor T , Guerra L , Brown JD , Reid C , McElroy CA , Dogan Ekici O , Callam CS , Hadad CM |
| Ref : ACS Med Chem Lett , 8 :622 , 2017 |
| Abstract : Yoder_2017_ACS.Med.Chem.Lett_8_622 |
| ESTHER : Yoder_2017_ACS.Med.Chem.Lett_8_622 |
| PubMedSearch : Yoder_2017_ACS.Med.Chem.Lett_8_622 |
| PubMedID: 28626522 |
| Title : Efforts toward treatments against aging of organophosphorus-inhibited acetylcholinesterase - Zhuang_2016_Ann.N.Y.Acad.Sci_1374_94 |
| Author(s) : Zhuang Q , Young A , Callam CS , McElroy CA , Ekici OD , Yoder RJ , Hadad CM |
| Ref : Annals of the New York Academy of Sciences , 1374 :94 , 2016 |
| Abstract : Zhuang_2016_Ann.N.Y.Acad.Sci_1374_94 |
| ESTHER : Zhuang_2016_Ann.N.Y.Acad.Sci_1374_94 |
| PubMedSearch : Zhuang_2016_Ann.N.Y.Acad.Sci_1374_94 |
| PubMedID: 27327269 |
| Title : High-Throughput Screening for Positive Allosteric Modulators Identified Potential Therapeutics against Acetylcholinesterase Inhibition - Chapleau_2015_J.Biomol.Screen_20_1142 |
| Author(s) : Chapleau RR , McElroy CA , Ruark CD , Fleming EJ , Ghering AB , Schlager JJ , Poeppelman LD , Gearhart JM |
| Ref : J Biomol Screen , 20 :1142 , 2015 |
| Abstract : Chapleau_2015_J.Biomol.Screen_20_1142 |
| ESTHER : Chapleau_2015_J.Biomol.Screen_20_1142 |
| PubMedSearch : Chapleau_2015_J.Biomol.Screen_20_1142 |
| PubMedID: 26078409 |