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| Title : Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012 - Melancon_2012_Bioorg.Med.Chem.Lett_22_1044 |
| Author(s) : Melancon BJ , Lamers AP , Bridges TM , Sulikowski GA , Utley TJ , Sheffler DJ , Noetzel MJ , Morrison RD , Daniels JS , Niswender CM , Jones CK , Conn PJ , Lindsley CW , Wood MR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :1044 , 2012 |
| Abstract : Melancon_2012_Bioorg.Med.Chem.Lett_22_1044 |
| ESTHER : Melancon_2012_Bioorg.Med.Chem.Lett_22_1044 |
| PubMedSearch : Melancon_2012_Bioorg.Med.Chem.Lett_22_1044 |
| PubMedID: 22197142 |
| Title : Muscarinic receptor pharmacology and circuitry for the modulation of cognition - Bubser_2012_Handb.Exp.Pharmacol_208_121 |
| Author(s) : Bubser M , Byun N , Wood MR , Jones CK |
| Ref : Handbook of Experimental Pharmacology , :121 , 2012 |
| Abstract : Bubser_2012_Handb.Exp.Pharmacol_208_121 |
| ESTHER : Bubser_2012_Handb.Exp.Pharmacol_208_121 |
| PubMedSearch : Bubser_2012_Handb.Exp.Pharmacol_208_121 |
| PubMedID: 22222698 |
| Title : Discovery of N-(4-methoxy-7-methylbenzo[d]thiazol-2-yl)isonicatinamide, ML293, as a novel, selective and brain penetrant positive allosteric modulator of the muscarinic 4 (M4) receptor - Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| Author(s) : Salovich JM , Vinson PN , Sheffler DJ , Lamsal A , Utley TJ , Blobaum AL , Bridges TM , Le U , Jones CK , Wood MR , Daniels JS , Conn PJ , Niswender CM , Lindsley CW , Hopkins CR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 22 :5084 , 2012 |
| Abstract : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| ESTHER : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| PubMedSearch : Salovich_2012_Bioorg.Med.Chem.Lett_22_5084 |
| PubMedID: 22738637 |
| Title : Allosteric modulation of seven transmembrane spanning receptors: theory, practice, and opportunities for central nervous system drug discovery - |
| Author(s) : Melancon BJ , Hopkins CR , Wood MR , Emmitte KA , Niswender CM , Christopoulos A , Conn PJ , Lindsley CW |
| Ref : Journal of Medicinal Chemistry , 55 :1445 , 2012 |
| PubMedID: 22148748 |
| Title : Discovery and optimization of a novel, selective and brain penetrant M1 positive allosteric modulator (PAM): the development of ML169, an MLPCN probe - Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
| Author(s) : Reid PR , Bridges TM , Sheffler DJ , Cho HP , Lewis LM , Days E , Daniels JS , Jones CK , Niswender CM , Weaver CD , Conn PJ , Lindsley CW , Wood MR |
| Ref : Bioorganic & Medicinal Chemistry Lett , 21 :2697 , 2011 |
| Abstract : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
| ESTHER : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
| PubMedSearch : Reid_2011_Bioorg.Med.Chem.Lett_21_2697 |
| PubMedID: 21194936 |
| Title : The antipsychotic potential of muscarinic allosteric modulation - Bridges_2010_Drug.News.Perspect_23_229 |
| Author(s) : Bridges TM , LeBois EP , Hopkins CR , Wood MR , Jones CK , Conn PJ , Lindsley CW |
| Ref : Drug News Perspect , 23 :229 , 2010 |
| Abstract : Bridges_2010_Drug.News.Perspect_23_229 |
| ESTHER : Bridges_2010_Drug.News.Perspect_23_229 |
| PubMedSearch : Bridges_2010_Drug.News.Perspect_23_229 |
| PubMedID: 20520852 |
| Title : Novel CGRP receptor antagonists through a design strategy of target simplification with addition of molecular flexibility - Wood_2009_Bioorg.Med.Chem.Lett_19_5787 |
| Author(s) : Wood MR , Schirripa KM , Kim JJ , Quigley AG , Stump CA , Bell IM , Bednar RA , Fay JF , Bruno JG , Moore EL , Mosser SD , Roller S , Salvatore CA , Kane SA , Vacca JP , Selnick HG |
| Ref : Bioorganic & Medicinal Chemistry Lett , 19 :5787 , 2009 |
| Abstract : Wood_2009_Bioorg.Med.Chem.Lett_19_5787 |
| ESTHER : Wood_2009_Bioorg.Med.Chem.Lett_19_5787 |
| PubMedSearch : Wood_2009_Bioorg.Med.Chem.Lett_19_5787 |
| PubMedID: 19703767 |