Thiohydrolase

Relationship

Family: Thiohydrolase

Block: X

Parent Family: Peptidase_S15

Comment

Under construction: extracted from Xaa-Pro-like_dom. Penicillium sp. Chain-fusing Polyketide Gregatin A GrgF belongs to this family. Thioesterase DcsB: A polyketide cyclase that forms medium-ring Lactones. The nucleophile can be Ser as in beab2-j4wat9 (Beauveria bassiana (White muscardine disease fungus) thioesterase DcsB) or Cys as in pensq-GrgF (Penicillium sp. Chain-fusing Polyketide Gregatin A GrgF). The C115S mutant functions as a thioesterase, while losing the ability to perform chain fusion.

Database

Interpro : IPR051411 Polyketide transferase af380 Polyketide_trans_af380

PIRSF : No PIRSF

Pdoc : No Pdoc

Pfam : No Pfam

Prints : No Print

EC Number : No EC Number

Sequences

Peptide in Fasta
Nucleotide in Fasta
Alignment with Multalin Text only
Seed alignment with MAFFT No colour / coloured with Mview
Alignment with MAFFT No colour / coloured with Mview
Dendrogram The dnd file

Structure Name Proteins
6LZH Structure of GrgF chain-fusing Polyketide Gregatin A pensq-GrgF
7D78 The structure of thioesterase DcsB. A polyketide cyclase that forms medium-ring lactones beab2-j4wat9
7D79 The structure of thioesterase DcsB. A polyketide cyclase that forms medium-ring lactones with its substrate analogue beab2-j4wat9

Gene_locus Name Species
9euro-a0a0u5cnn8 Aspergillus calidoustus. AB hydrolase-1 domain-containing protein Aspergillus calidoustus
9euro-a0a0u5fnb7 Aspergillus calidoustus. Hydrolase_4 domain-containing protein Aspergillus calidoustus
9euro-a0a101mju4 Penicillium freii. AB hydrolase-1 domain-containing protein Penicillium freii
9euro-a0a1q5t232 Penicillium subrubescens. Peptidase_S15 domain-containing protein Penicillium subrubescens
9euro-a0a1v6rmr7 Penicillium vulpinum. Hydrolase_4 domain-containing protein Penicillium vulpinum
9euro-a0a1v6rn82 Penicillium vulpinum. Hydrolase_4 domain-containing protein Penicillium vulpinum
9euro-a0a1v6rzv4 Penicillium vulpinum. AB hydrolase-1 domain-containing protein Penicillium vulpinum
9euro-a0a1v6twy6 Penicillium flavigenum. Hydrolase_4 domain-containing protein Penicillium flavigenum
9euro-a0a1v6u8q7 Penicillium coprophilum. AB hydrolase-1 domain-containing protein Penicillium coprophilum
9euro-a0a1v6uc89 Penicillium coprophilum. AB hydrolase-1 domain-containing protein Penicillium coprophilum
9euro-a0a225arg9 Talaromyces atroroseus. DLH domain-containing protein Talaromyces atroroseus
9euro-a0a225b3q6 Talaromyces atroroseus. Hydrolase_4 domain-containing protein Talaromyces atroroseus
9euro-a0a2b7xp46 Helicocarpus griseus UAMH5409. Hydrolase_4 domain-containing protein Helicocarpus griseus UAMH5409
9euro-a0a2i2g4i4 Aspergillus steynii IBT 23096. Alpha\/beta-hydrolase Aspergillus steynii IBT 23096
9euro-a0a318zb88 Aspergillus saccharolyticus JOP 1030-1. Alpha\/beta-hydrolase Aspergillus saccharolyticus JOP 1030-1
9euro-a0a319cft9 Aspergillus uvarum CBS 121591. DltD N-terminal domain protein Aspergillus uvarum CBS 121591
9euro-a0a319dq76 Aspergillus ellipticus CBS 707.79. Alpha\/beta-hydrolase Aspergillus ellipticus CBS 707.79
9euro-a0a364kr31 Talaromyces amestolkiae. Hydrolase_4 domain-containing protein Talaromyces amestolkiae
9euro-a0a395ha60 Aspergillus ibericus CBS 121593. Alpha\/beta-hydrolase Aspergillus ibericus CBS 121593
9euro-a0a397g056 Aspergillus thermomutatus. Hydrolase_4 domain-containing protein Aspergillus thermomutatus
9euro-a0a397gbs5 Aspergillus thermomutatus. Uncharacterized protein Aspergillus thermomutatus
9euro-a0a3d8rk78 Aspergillus mulundensis. AB hydrolase-1 domain-containing protein Aspergillus mulundensis
9euro-a0a4s3jbr2 Aspergillus tanneri. AB hydrolase-1 domain-containing protein Aspergillus tanneri
9euro-a0a510nxp1 Talaromyces cellulolyticus. AB hydrolase-1 domain-containing protein Talaromyces cellulolyticus
9euro-a0a5n6tf90 Aspergillus avenaceus. Alpha\/beta-hydrolase Aspergillus avenaceus
9euro-a0a5n6u0a1 Aspergillus avenaceus. Alpha\/Beta hydrolase protein Aspergillus avenaceus
9euro-a0a5n7a8s9 Aspergillus caelatus. Alpha\/beta-hydrolase Aspergillus caelatus
9euro-a0a6v8hq83 Talaromyces cellulolyticus\; Penicillium sp. 'occitanis'. Uncharacterized protein Talaromyces cellulolyticus
9fung-a0a1v1tad4 fungal sp. No.14919. Hydrolase_4 domain-containing protein fungal sp. No.14919
9helo-a0a194wyn0 Phialocephala scopiformis. Alpha\/beta-hydrolase Phialocephala scopiformis
9helo-a0a194xhg5 Phialocephala scopiformis. Alpha\/beta-hydrolase Phialocephala scopiformis
9helo-a0a1l7xsf8 Phialocephala subalpina. Related to DltD N-terminal domain protein Phialocephala subalpina
9helo-a0a2j6rlz5 Hyaloscypha variabilis F. Alpha\/beta-hydrolase Hyaloscypha variabilis F
9helo-a0a2j6sux5 Hyaloscypha bicolor E. Peptidase S15 Hyaloscypha bicolor E
9helo-a0a2j6sxe7 Hyaloscypha bicolor E. Alpha\/beta-hydrolase Hyaloscypha bicolor E
9helo-a0a2s7nnt1 Rutstroemia sp. NJR-2017a AB hydrolase-1 domain-containing protein Rutstroemia sp. NJR-2017a BBW
9helo-a0a2s7nqr2 Rutstroemia sp. NJR-2017a BVV2. Hydrolase_4 domain-containing protein Rutstroemia sp. NJR-2017a BVV2
9helo-a0a2s7q3r7 Rutstroemia sp. NJR-2017a Hydrolase_4 domain-containing protein Rutstroemia sp. NJR-2017a BBW
9helo-a0a2v1buk5 Cadophora sp. DSE1049. Alpha\/beta-hydrolase Cadophora sp. DSE1049
9helo-a0a370tat5 Venustampulla echinocandica. AB hydrolase-1 domain-containing protein Venustampulla echinocandica
9helo-a0a370u370 Venustampulla echinocandica. AB hydrolase-1 domain-containing protein Venustampulla echinocandica
9helo-a0a3d8s0y2 Coleophoma cylindrospora. AB hydrolase-1 domain-containing protein Coleophoma cylindrospora
9helo-a0a3d8stp9 Coleophoma cylindrospora. Peptidase_S15 domain-containing protein Coleophoma cylindrospora
9helo-a0a4y8d950 Botryotinia calthae. BAAT_C domain-containing protein Botryotinia calthae
9helo-a0a4z1iba1 Botryotinia narcissicola. AXE1 domain-containing protein Botryotinia narcissicola
9helo-a0a4z1j122 Botryotinia narcissicola. AB hydrolase-1 domain-containing protein Botryotinia narcissicola
9helo-a0a4z1jw23 Botrytis elliptica. Hydrolase_4 domain-containing protein Botrytis elliptica
9helo-a0a559mer2 Lachnellula willkommii. Polyketide transferase Lachnellula willkommii
9hypo-a0a0f7zmp5 Hirsutella minnesotensis 3608. AB hydrolase-1 domain-containing protein Hirsutella minnesotensis 3608
9hypo-a0a0p7ayj2 Neonectria ditissima. AB hydrolase-1 domain-containing protein Neonectria ditissima
9hypo-a0a2k3pzj1 Tolypocladium capitatum. 31.7 kDa protein in traX-finO intergenic region Tolypocladium capitatum
9hypo-a0a2s4ky45 Tolypocladium paradoxum. DltD N-terminal domain protein Tolypocladium paradoxum
9hypo-a0a367l4b5 Ophiocordyceps polyrhachis-furcata BCC 54312. BAAT_C domain-containing protein Ophiocordyceps polyrhachis-furcata BCC 54312
9hypo-a0a369gx05 Ophiocordyceps camponoti-leonardi (nom. inval.). Uncharacterized protein Ophiocordyceps camponoti-leonardi
9hypo-a0a545vqi9 Cordyceps javanica. DltD N-terminal domain-containing protein Cordyceps javanica
9pezi-a0a010qyb2 Colletotrichum fioriniae PJ7. DltD domain-containing protein Colletotrichum fioriniae PJ7
9pezi-a0a093z620 Pseudogymnoascus sp. Hydrolase_4 domain-containing protein Pseudogymnoascus sp. VKM F-4246
9pezi-a0a093zrg0 Pseudogymnoascus sp. Peptidase_S15 domain-containing protein Pseudogymnoascus sp. VKM F-4246
9pezi-a0a094ca10 Pseudogymnoascus sp. VKM F-3775. AB hydrolase-1 domain-containing protein Pseudogymnoascus sp. VKM F-3775
9pezi-a0a094ch86 Pseudogymnoascus sp. VKM F-4515 (FW-2607). Uncharacterized protein Pseudogymnoascus sp. VKM F-4515 (FW-2607)
9pezi-a0a094fmg1 Pseudogymnoascus sp.. Uncharacterized protein Pseudogymnoascus sp. VKM F-4516 (FW-969)
9pezi-a0a094hn35 Pseudogymnoascus sp.\; Pseudogymnoascus verrucosus, Hydrolase_4 domain-containing protein Pseudogymnoascus sp. VKM F-4520 (FW-2644)
9pezi-a0a0g4li73 Verticillium longisporum\; Verticillium dahliae (Verticillium wilt). Hydrolase_4 domain-containing protein Verticillium longisporum
9pezi-a0a136jcx1 Microdochium bolleyi. Alpha\/Beta hydrolase protein Microdochium bolleyi
9pezi-a0a161yah9 Colletotrichum incanum. Hydrolase_4 domain-containing protein Colletotrichum incanum
9pezi-a0a166vaq1 Colletotrichum tofieldiae. N-terminal alpha\/beta hydrolase domain protein Colletotrichum tofieldiae
9pezi-a0a175vzn4 Madurella mycetomatis. Hydrolase_4 domain-containing protein Madurella mycetomatis
9pezi-a0a175wil5 Madurella mycetomatis. Hydrolase_4 domain-containing protein Madurella mycetomatis
9pezi-a0a194v2d2 Valsa mali var. pyri. AB hydrolase-1 domain-containing protein Valsa mali var. pyri
9pezi-a0a194vat3 Valsa mali var. pyri. AB hydrolase-1 domain-containing protein Valsa mali var. pyri
9pezi-a0a1b8dcw7 Pseudogymnoascus sp. 24MN13. AB hydrolase-1 domain-containing protein Pseudogymnoascus sp. 24MN13
9pezi-a0a1b8dwu3 Pseudogymnoascus sp. 23342-1-I1. Uncharacterized protein Pseudogymnoascus sp. 23342-1-I1
9pezi-a0a1y2ufj7 Hypoxylon sp. CO27-5. Hydrolase_4 domain-containing protein Hypoxylon sp. CO27-5
9pezi-a0a1y2vvc9 Hypoxylon sp. CI-4A. Hydrolase_4 domain-containing protein Hypoxylon sp. CI-4A
9pezi-a0a1y2w3w4 Hypoxylon sp. CI-4A. AB hydrolase-1 domain-containing protein Hypoxylon sp. CI-4A
9pezi-a0a2p5hnk6 Diaporthe helianthi. DltD domain-containing protein Diaporthe helianthi
9pezi-a0a2t3a098 Coniella lustricola. Alpha\/Beta hydrolase protein Coniella lustricola
9pezi-a0a3n2puy7 Sodiomyces alkalinus F11. DltD N-terminal domain protein Sodiomyces alkalinus F11
9pezi-a0a420y255 Coniochaeta pulveracea. AB hydrolase-1 domain-containing protein Coniochaeta pulveracea
9pezi-a0a423v860 Valsa malicola. AB hydrolase-1 domain-containing protein Valsa malicola
9pezi-a0a423v888 Valsa sordida. AB hydrolase-1 domain-containing protein Valsa sordida
9pezi-a0a423vnj3 Valsa malicola. Hydrolase_4 domain-containing protein Valsa malicola
9pezi-a0a423x433 Valsa malicola. FAD-binding PCMH-type domain-containing protein Valsa malicola
9pezi-a0a423xfw7 Cytospora leucostoma. AB hydrolase-1 domain-containing protein Cytospora leucostoma
9pezi-a0a423xh30 Cytospora leucostoma. AB hydrolase-1 domain-containing protein Cytospora leucostoma
9pezi-a0a439csc5 Xylaria grammica\; fungal sp. AB hydrolase-1 domain-containing protein Xylaria grammica
9pezi-a0a439cxb1 Xylaria grammica. Hydrolase_4 domain-containing protein Xylaria grammica
9pezi-a0a439d4t2 Xylaria grammica\; fungal sp. Hydrolase_4 domain-containing protein Xylaria grammica
9pezi-a0a439d670 Xylaria grammica. AB hydrolase-1 domain-containing protein Xylaria grammica
9pezi-a0a439d6i5 Xylaria grammica\; fungal sp.. Hydrolase_4 domain-containing protein Xylaria grammica
9pezi-a0a439dap1 Xylaria grammica. Hydrolase_4 domain-containing protein Xylaria grammica
9pezi-a0a439di44 Xylaria grammica\; fungal sp. Hydrolase_4 domain-containing protein Xylaria grammica
9pezi-a0a4q4u671 Monosporascus sp. MC13-8B. Hydrolase_4 domain-containing protein Monosporascus sp. MC13-8B
9pezi-a0a4q4uut9 Monosporascus sp. GIB2. Hydrolase_4 domain-containing protein Monosporascus sp. GIB2
9pezi-a0a4q4wax4 Monosporascus sp. mg162. AB hydrolase-1 domain-containing protein Monosporascus sp. mg162
9pezi-a0a4q4wrt6 Monosporascus sp. mg162. AB hydrolase-1 domain-containing protein Monosporascus sp. mg162
9pezi-a0a4q4xk22 Monosporascus sp. 5C6A. AB hydrolase-1 domain-containing protein Monosporascus sp. 5C6A
9pezi-a0a4q4xuf1 Monosporascus sp. 5C6A. AB hydrolase-1 domain-containing protein Monosporascus sp. 5C6A
9pezi-a0a4q4y2x4 Monosporascus sp. 5C6A. Hydrolase_4 domain-containing protein Monosporascus sp. 5C6A
9pezi-a0a4q4yza6 Monosporascus sp. CRB-9-2. Hydrolase_4 domain-containing protein Monosporascus sp. CRB-9-2
9pezi-a0a4z0ygq2 Xylaria hypoxylon. AB hydrolase-1 domain-containing protein Xylaria hypoxylon
9pezi-a0a4z0yhs9 Xylaria hypoxylon. Hydrolase_4 domain-containing protein Xylaria hypoxylon
9pezi-a0a4z0zbv9 Xylaria hypoxylon. Hydrolase_4 domain-containing protein Xylaria hypoxylon
9pezi-a0a553hp65 Xylaria flabelliformis. AB hydrolase-1 domain-containing protein Xylaria flabelliformis
9pezi-a0a553hpu5 Xylaria flabelliformis. PKS_ER domain-containing protein Xylaria flabelliformis
9pezi-a0a5n5d4q0 Lasiodiplodia theobromae. Polyketide transferase Lasiodiplodia theobromae
9pleo-a0a177cd19 Paraphaeosphaeria sporulosa. Alpha\/beta-hydrolase Paraphaeosphaeria sporulosa
9pleo-a0a177cg53 Paraphaeosphaeria sporulosa. Alpha\/beta-hydrolase Paraphaeosphaeria sporulosa
9pleo-a0a364n6u1 Stemphylium lycopersici. Peptidase S15 Stemphylium lycopersici
amore-a0a2t3aph0 Amorphotheca resinae ATCC 22711. AB hydrolase-1 domain-containing protein Amorphotheca resinae ATCC 22711
artpe-apmlb Arthrinium phaeospermum (Gymnosporium phaeospermum). Phaeospelide A biosynthesis cluster protein apmlB Arthrinium phaeospermum
aspa1-anee Aspergillus aculeatus (strain ATCC 16872 \/ CBS 172.66 \/ WB 5094). Aculenes biosynthesis cluster protein E Aspergillus aculeatus
aspbc-a0a1l9uy89 Aspergillus brasiliensis (strain CBS 101740 \/ IMI 381727 \/ IBT 21946). AB hydrolase-1 domain-containing protein Aspergillus brasiliensis
aspc5-a0a1r3rem6 Aspergillus carbonarius (strain ITEM 5010). AB hydrolase-1 domain-containing protein Aspergillus carbonarius
aspfu-fmac Neosartorya fumigata (strain ATCC MYA-4609 \/ Af293 \/ CBS 101355 \/ FGSC A1100) (Aspergillus fumigatus). Fumagillin biosynthesis acyltransferase Neosartorya fumigata
aspkw-g7xen3 Aspergillus kawachii (strain NBRC 4308) (White koji mold) (Aspergillus awamori var. kawachi). DltD N-terminal domain protein Aspergillus kawachii
aspng-a0a100i8t9 Aspergillus niger\; Aspergillus tubingensis. AB hydrolase-1 domain-containing protein Aspergillus niger
aspno-a0a0l1j1g1 Aspergillus nomiae\; Aspergillus pseudonomius\; Aspergillus bombycis. Hydrolase_4 domain-containing protein Aspergillus nomiae NRRL 13137
aspsb-a0a319e203 Aspergillus sclerotiicarbonarius (strain CBS 121057 \/ IBT 28362). Alpha\/beta-hydrolase Aspergillus sclerotiicarbonarius
asptn-q0cnl5 Aspergillus terreus (strain NIH 2624 \/ FGSC A1156). Hydrolase_4 domain-containing protein Aspergillus terreus
beab2-j4wat9 Beauveria bassiana (White muscardine disease fungus) (Tritirachium shiotae) DltD domain-containing protein. thioesterase DcsB Beauveria bassiana ARSEF 2860
beaba-a0a2n6n8e6 Beauveria bassiana (White muscardine disease fungus) (Tritirachium shiotae). Putative 31 protein in traX-finO intergenic region Beauveria bassiana
botf1-m7uct5 Botryotinia fuckeliana(Noble rot fungus) (Botrytis cinerea)\; Botryotinia calthae. Putative n-terminal domain protein Botryotinia fuckeliana
botpv-r1gaa8 Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus) (Neofusicoccum parvum). Putative n-terminal domain protein Botryosphaeria parva
botpv-r1ghe4 Botryosphaeria parva (strain UCR-NP2) (Grapevine canker fungus) (Neofusicoccum parvum). Putative n-terminal domain protein Botryosphaeria parva
byssn-v5i511 Byssochlamys spectabilis (strain No. 5 \/ NBRC 109023) (Paecilomyces variotii). Hydrolase_4 domain-containing protein Byssochlamys spectabilis
chagb-q2h2d0 Chaetomium globosum (strain ATCC 6205 \/ CBS 148.51 \/ DSM 1962 \/ NBRC 6347 \/ NRRL 1970) (Soil fungus). AB hydrolase-1 domain-containing protein Chaetomium globosum
cocsn-m2sl21 Cochliobolus sativus (strain ND90Pr \/ ATCC 201652) (Common root rot and spot blotch fungus) (Bipolaris sorokiniana). Hydrolase_4 domain-containing protein Cochliobolus sativus
colgc-t0kem7 Colletotrichum gloeosporioides (strain Cg-14) (Anthracnose fungus) (Glomerella cingulata). AB hydrolase-1 domain-containing protein Colletotrichum gloeosporioides
colgc-t0m975 Colletotrichum gloeosporioides (Anthracnose fungus) (Glomerella cingulata)\; Colletotrichum fructicola. AB hydrolase-1 domain-containing protein Colletotrichum gloeosporioides
colgm-e3qx16 Colletotrichum graminicola (strain M1.001 \/ M2 \/ FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola). DltD domain-containing protein Colletotrichum graminicola
colsu-a0a066xqi8 Colletotrichum sublineola (Sorghum anthracnose fungus). AB hydrolase-1 domain-containing protein Colletotrichum sublineola
corcc-a0a2t2n262 Corynespora cassiicola Philippines. Alpha\/beta-hydrolase Corynespora cassiicola Philippines
corcc-a0a2t2nt04 Corynespora cassiicola Philippines\; Periconia macrospinosa. Alpha\/beta-hydrolase Corynespora cassiicola Philippines
cordf-a0a179ib68 Cordyceps confragosa (Lecanicillium lecanii)\; Akanthomyces lecanii DltD Hydrolase_4 domain-containing protein Cordyceps confragosa
corfa-a0a167q5m2 Cordyceps fumosorosea (strain ARSEF 2679) (Isaria fumosorosea). DltD N-terminal domain protein Cordyceps fumosorosea
cormm-g3jpf2 Cordyceps militaris (strain CM01) (Caterpillar fungus). DltD N-terminal domain protein Cordyceps militaris
emeni-q5ax97 Emericella nidulans (strain FGSC A4 \/ ATCC 38163 \/ CBS 112.46 \/ NRRL 194 \/ M139) (Aspergillus nidulans). DltD N-terminal domain protein (AFU_orthologue AFUA_8G00380) Emericella nidulans
endpu-u1gu60 Endocarpon pusillum (strain Z07020 \/ HMAS-L-300199) (Lichen-forming fungus). Hydrolase_4 domain-containing protein Endocarpon pusillum
eupbr-bref2 Eupenicillium brefeldianum (Penicillium brefeldianum). Brefeldin A biosynthesis cluster protein Bref-TH Eupenicillium brefeldianum
exodn-h6c4y3 Exophiala dermatitidis (strain ATCC 34100 \/ CBS 525.76 \/ NIH\/UT8656) (Black yeast) (Wangiella dermatitidis). Hydrolase_4 domain-containing protein Exophiala dermatitidis
gibf5-fuj3 Gibberella fujikuroi (strain CBS 195.34 \/ IMI 58289 \/ NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi). Fujikurins biosynthesis cluster protein FFUJ_12241 Gibberella fujikuroi
gibm7-w7n4n0 Gibberella moniliformis (Maize ear and stalk rot fungus) (Fusarium verticillioides)\; Gibberella nygamai (Bean root rot disease fungus) (Fusarium nygamai).\; Fusarium oxysporum, Hydrolase_4 domain-containing protein Gibberella moniliformis
hypvg-g9muj2 Hypocrea virens (strain Gv29-8 \/ FGSC 10586) (Gliocladium virens) (Trichoderma virens). Hydrolase_4 domain-containing protein Hypocrea virens
macph-k2res7 Macrophomina phaseolina (strain MS6) (Charcoal rot fungus). Acetyl xylan esterase Macrophomina phaseolina
macph-k2rnn6 Macrophomina phaseolina (strain MS6) (Charcoal rot fungus). Hydrolase_4 domain-containing protein Macrophomina phaseolina
macph-k2s7y7 Macrophomina phaseolina (strain MS6) (Charcoal rot fungus). AB hydrolase-1 domain-containing protein Macrophomina phaseolina
magp6-a0a0c4ebx4 Magnaporthiopsis poae (strain ATCC 64411 \/ 73-15) (Kentucky bluegrass fungus) (Magnaporthe poae). Uncharacterized protein Magnaporthiopsis poae
metan-a0a0d9nta1 Metarhizium anisopliae BRIP 53293. Hydrolase_4 domain-containing protein Metarhizium anisopliae BRIP 53293
monfr-a0a5m9jb00 Monilinia fructicola (Brown rot fungus) (Ciboria fructicola). Hydrolase_4 domain-containing protein Monilinia fructicola
neofi-a1d5e6 Neosartorya fischeri (strain ATCC 1020 \/ DSM 3700 \/ CBS 544.65 \/ FGSC A1164 \/ JCM 1740 \/ NRRL 181 \/ WB 181) (Aspergillus fischerianus). Hydrolase_4 domain-containing protein Neosartorya fischeri
neofi-a1da82 Neosartorya fischeri (Aspergillus fischerianus)\; Aspergillus novofumigatus\; Aspergillus udagawae\; Penicillium arizonense. Hydrolase_4 domain-containing protein Neosartorya fischeri
penbi-a0a0f7tzk4 Penicillium brasilianum. AB hydrolase-1 domain-containing protein Penicillium brasilianum
penca-a0a0g4pxg3 Penicillium camemberti Penicillium polonicum\; Penicillium nordicum Alpha\/beta-hydrolase Penicillium camemberti FM 013
pencr-clah Penicillium crustosum (Blue mold fungus). Clavatol biosynthesis cluster protein H Penicillium crustosum
penen-a0a0a2ipm7 Penicillium expansum (Blue mold rot fungus). Hydrolase_4 domain-containing protein Penicillium expansum
penen-a0a0a2j4q8 Penicillium expansum (Blue mold rot fungus). AB hydrolase-1 domain-containing protein Penicillium expansum
penit-a0a0a2kwb1 Penicillium italicum (Blue mold). AB hydrolase-1 domain-containing protein Penicillium italicum
penit-a0a0a2l0j9 Penicillium italicum (Blue mold). AB hydrolase-1 domain-containing protein Penicillium italicum
penna-a0a1v6ynj7 Penicillium nalgiovense. Hydrolase_4 domain-containing protein Penicillium nalgiovense
penpa-a0a135ljx5 Penicillium patulum (Penicillium griseofulvum). Peptidase_S15 domain-containing protein Penicillium patulum
penpa-a0a135ln75 Penicillium patulum (Penicillium griseofulvum). AB hydrolase-1 domain-containing protein Penicillium patulum
pensq-GrgF Penicillium sp. alpha\/beta hydrolase fold protein. Chain-fusing Polyketide Gregatin A GrgF Penicillium sp.
pesfw-w3whp0 Pestalotiopsis fici (strain W106-1 \/ CGMCC3.15140). AB hydrolase-1 domain-containing protein Pestalotiopsis fici
pesfw-w3wrn9 Pestalotiopsis fici (strain W106-1 \/ CGMCC3.15140). Hydrolase_4 domain-containing protein Pestalotiopsis fici
pesfw-w3x341 Pestalotiopsis fici (strain W106-1 \/ CGMCC3.15140). AB hydrolase-1 domain-containing protein Pestalotiopsis fici
pesfw-w3xc39 Pestalotiopsis fici (strain W106-1 \/ CGMCC3.15140). AB hydrolase-1 domain-containing protein Pestalotiopsis fici
petaa-a0a5n6faq7 Petromyces alliaceus (Aspergillus alliaceus). DltD N-terminal domain protein Petromyces alliaceus
phano-q0twn7 Phaeosphaeria nodorum (strain SN15 \/ ATCC MYA-4574 \/ FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum). Hydrolase_4 domain-containing protein Phaeosphaeria nodorum
pseda-a0a084g1s9 Pseudallescheria apiosperma (Scedosporium apiospermum). Peptidase_S15 domain-containing protein Pseudallescheria apiosperma
purli-a0a179ggw4 Purpureocillium lilacinum (Paecilomyces lilacinus). Peptidase S15 Purpureocillium lilacinum
pyrtt-e3rgu8 Pyrenophora teres f. teres (strain 0-1) (Barley net blotch fungus) (Drechslera teres f. teres). Hydrolase_4 domain-containing protein Pyrenophora teres f. teres
rosne-a0a1w2tfp3 Rosellinia necatrix (White root-rot fungus). Putative n-terminal domain protein Rosellinia necatrix
rosne-a0a1w2tp45 Rosellinia necatrix (White root-rot fungus). Putative peptidase s15 Rosellinia necatrix
rosne-a0a1w2tts7 Rosellinia necatrix (White root-rot fungus). Hydrolase_4 domain-containing protein Rosellinia necatrix
scls1-a7ea78 Sclerotinia sclerotiorum (strain ATCC 18683 \/ 1980 \/ Ss-1) (White mold) (Whetzelinia sclerotiorum). Uncharacterized protein Sclerotinia sclerotiorum
stac4-atr5 Stachybotrys chlorohalonata (strain IBT 40285). Core atranone cluster (CAC) protein 5 Stachybotrys chlorohalonata
talis-a0a0u1lru5 Talaromyces islandicus (Penicillium islandicum). AB hydrolase-1 domain-containing protein Talaromyces islandicus
thett-g2qur2 Thermothielavioides terrestris (strain ATCC 38088 \/ NRRL 8126) (Thielavia terrestris). Hydrolase_4 domain-containing protein Thermothielavioides terrestris
triar-a0a395nkh6 Trichoderma arundinaceum. N-terminal domain Trichoderma arundinaceum
triar-a0a395nq82 Trichoderma arundinaceum. N-terminal domain Trichoderma arundinaceum
zymti-f9xfj3 Zymoseptoria tritici (Speckled leaf blotch fungus) (Septoria tritici)\; Zymoseptoria brevis. Hydrolase_4 domain-containing protein Zymoseptoria tritici

Gene_locus_frgt Name Species
9helo-a0a5n6jxd6 Monilinia laxa. Hydrolase_4 domain-containing protein Monilinia laxa
9pezi-a0a4q4vxj6 Monosporascus sp. MG133. Uncharacterized protein Monosporascus sp. MG133
9pezi-a0a4v1xmb0 Monosporascus sp. mg162. AB hydrolase-1 domain-containing protein Monosporascus sp. mg162

Substrate Chemical Nomenclature Proteins
GY0 methyl 3-[(E,3R,9R)-3,9-bis(oxidanyl)dec-4-enoyl]sulfanylpropanoate beab2-j4wat9

References (2)

Title : A Polyketide Cyclase That Forms Medium-Ring Lactones - Gao_2021_J.Am.Chem.Soc_143_80
Author(s) : Gao DW , Jamieson CS , Wang G , Yan Y , Zhou J , Houk KN , Tang Y
Ref : Journal of the American Chemical Society , 143 :80 , 2021
Abstract :
PubMedSearch : Gao_2021_J.Am.Chem.Soc_143_80
PubMedID: 33351624
Gene_locus related to this paper: beab2-j4wat9

Title : Molecular Basis for the Biosynthesis of an Unusual Chain-Fused Polyketide Gregatin A - Wang_2020_J.Am.Chem.Soc_142_8464
Author(s) : Wang WG , Wang H , Du LQ , Li M , Chen L , Yu J , Cheng GG , Zhan MT , Hu QF , Zhang L , Yao M , Matsuda Y
Ref : Journal of the American Chemical Society , 142 :8464 , 2020
Abstract :
PubMedSearch : Wang_2020_J.Am.Chem.Soc_142_8464
PubMedID: 32275405
Gene_locus related to this paper: pensq-GrgF