burxl-bphD

Burkholderia xenovorans 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase gene bphD

Comment

Relationship

Family : Carbon-carbon_bond_hydrolase

Block : X

Position in NCBI Life Tree : Burkholderia xenovorans LB400

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Bacteria N E > Proteobacteria N E > Betaproteobacteria N E > Burkholderiales N E > Burkholderiaceae N E > Paraburkholderia N E > Paraburkholderia xenovorans N E > Paraburkholderia xenovorans LB400 N E

Molecular evidence

No mutation

No kinetic

No disease

No inhibitor

Database

Sequence

Peptide

MTALTESSTS KFVKINEKGF SDFNIHYNEA GNGETVIMLH GGGPGAGGWS NYYRNVGPFV DAGYRVILKD SPGFNKSDAV VMDEQRGLVN ARAVKGLMDA LDIDRAHLVG NSMGGATALN FALEYPDRIG KLILMGPGGL GPSMFAPMPM EGIKLLFKLY AEPSYETLKQ MLQVFLYDQS LITEELLQGR WEAIQRQPEH LKNFLISAQK APLSTWDVTA RLGEIKAKTF ITWGRDDRFV PLDHGLKLLW NIDDARLHVF SKCGHWAQWE HADEFNRLVI DFLRHA

References (8)

Title : A water-assisted nucleophilic mechanism utilized by BphD, the meta-cleavage product hydrolase in biphenyl degradation - Dong_2017_J.Mol.Graph.Model_76_448
Author(s) : Dong L , Zhang S , Liu Y
Ref : J Mol Graph Model , 76 :448 , 2017
PubMedID: 28783597
Gene_locus related to this paper: burxl-bphD

Title : Identification of an Acyl-Enzyme Intermediate in a meta-Cleavage Product Hydrolase Reveals the Versatility of the Catalytic Triad - Ruzzini_2012_J.Am.Chem.Soc_134_4615
Author(s) : Ruzzini AC , Ghosh S , Horsman GP , Foster LJ , Bolin JT , Eltis LD
Ref : J Am Chem Soc , 134 :4615 , 2012
PubMedID: 22339283
Gene_locus related to this paper: burxl-bphD

Title : The molecular basis for inhibition of BphD, a C-C bond hydrolase involved in polychlorinated biphenyls degradation: large 3-substituents prevent tautomerization - Bhowmik_2007_J.Biol.Chem_282_36377
Author(s) : Bhowmik S , Horsman GP , Bolin JT , Eltis LD
Ref : Journal of Biological Chemistry , 282 :36377 , 2007
PubMedID: 17932031
Gene_locus related to this paper: burxl-bphD

Title : The tautomeric half-reaction of BphD, a C-C bond hydrolase. Kinetic and structural evidence supporting a key role for histidine 265 of the catalytic triad - Horsman_2007_J.Biol.Chem_282_19894
Author(s) : Horsman GP , Bhowmik S , Seah SY , Kumar P , Bolin JT , Eltis LD
Ref : Journal of Biological Chemistry , 282 :19894 , 2007
PubMedID: 17442675
Gene_locus related to this paper: burxl-bphD

Title : Kinetic and structural insight into the mechanism of BphD, a C-C bond hydrolase from the biphenyl degradation pathway - Horsman_2006_Biochemistry_45_11071
Author(s) : Horsman GP , Ke J , Dai S , Seah SY , Bolin JT , Eltis LD
Ref : Biochemistry , 45 :11071 , 2006
PubMedID: 16964968
Gene_locus related to this paper: burxl-bphD

Title : Identification of a serine hydrolase as a key determinant in the microbial degradation of polychlorinated biphenyls - Seah_2000_J.Biol.Chem_275_15701
Author(s) : Seah SY , Labbe G , Nerdinger S , Johnson MR , Snieckus V , Eltis LD
Ref : Journal of Biological Chemistry , 275 :15701 , 2000
PubMedID: 10821847
Gene_locus related to this paper: burxl-bphD

Title : Purification and preliminary characterization of a serine hydrolase involved in the microbial degradation of polychlorinated biphenyls - Seah_1998_J.Biol.Chem_273_22943
Author(s) : Seah SY , Terracina G , Bolin JT , Riebel P , Snieckus V , Eltis LD
Ref : Journal of Biological Chemistry , 273 :22943 , 1998
PubMedID: 9722515
Gene_locus related to this paper: burxl-bphD

Title : Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl\/polychlorinated biphenyl degradation - Hofer_1993_Gene_130_47
Author(s) : Hofer B , Eltis LD , Dowling DN , Timmis KN
Ref : Gene , 130 :47 , 1993
PubMedID: 8344527
Gene_locus related to this paper: burxl-bphD