crigr-g3i7x7

Cricetulus griseus (Chinese hamster) Liver carboxylesterase 1

Comment

Relationship

Family : Carb_B_Chordata

Block : C

Position in NCBI Life Tree : Cricetulus griseus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Cricetidae N E > Cricetinae N E > Cricetulus N E > Cricetulus griseus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No inhibitor

Database

Sequence

Peptide

MWLCTFVLTF LTACLTQGHP PSPPIVDTVH GKVLGKYVSL EGFTQPVAIF LGVPFAKPPL GSLRFAPPQS AEPWSFVKNA TSYPPMCSQD PAAGQMLSAL FTNRKETIPL TFSEDCLYLN IYTPADLTKS SRLPVMVWIH GGGLVDGAST YDGLPLSAHE NVVVVTIQYR LGIWGFFSTQ DEHSRGNWGH LDQVAALHWV QDNIANFGGD PGSVTIFGES AGGASVSVLV LSPLAKNLFH RAISQSSVIL NPCLFGRDAR PIAERVAALA GCKTTTSAAM VHCLRQKTED ELLEITKKMK FGALDFLGDP RESYPFLPTV IDGVVLPKTP EEILAEKSFN TVPYMVGINK QEFGWSMPMM IGFPLSEDKL DQKRTTSLLW QSYPILNISE SLIPAAIEKY LSGTDNPIRK KDLLLDLMGD VMFGVPSVIV SRGHRDAGAP TYMYEFQYLP SFVSDMRPKT VKGDHGDDLF SVWGAPFLKE GASEEEINLS KMVMKFWGNF ARNGNPNGEG LPHWPEYDQK EGYLQIGVPT QAAHRLKDKE VAFWTELRAK EPAERPTQRK HVEL

References (1)

Title : Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development - Zhang_2020_J.Pharm.Sci_109_3300
Author(s) : Zhang S , Xiao H , Molden R , Qiu H , Li N
Ref : J Pharm Sci , 109 :3300 , 2020
Abstract :
PubMedSearch : Zhang_2020_J.Pharm.Sci_109_3300
PubMedID: 32721471
Gene_locus related to this paper: crigr-g3i7x7 , crigr-a0a061i7x9