geoca-1lipa

Galactomyces geotrichum (Geotrichum candidum) (Oospora lactis) (Dipodascus geotrichum) (Geotrichum sp. DTQ-26.3) protein for triacylglycerol lipase I

Comment

Dipodascus geotrichum From Bertolini et al: Characterization of different lipase isoforms from various G candidum strains is difficult. Each strain contains two genes similar to the previously identified lipase I and lipase II: Lipase I :(PIR S59958 CBS178.71 , PIR S41090 ATCC 34614 , PIR S41091 NRCC 205002, PIR S41092 NRRL Y-552 and PIR S41093 NRRL Y 553) || q1zzv0 from Galactomyces geotrichum BT107, A0FLP5 from Geotrichum sp. DTQ-26.3 || Dipodascus geotrichum

Relationship

Family : Fungal_carboxylesterase_lipase

Block : C

Position in NCBI Life Tree : Galactomyces geotrichum

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Saccharomycotina N E > Saccharomycetes N E > Saccharomycetales N E > Dipodascaceae N E > Galactomyces N E > Galactomyces candidum N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No inhibitor

Sequence

Peptide

QAPTAVLNGN EVISGVLEGK VDTFKGIPFA DPPVGDLRFK HPQPFTGSYQ GLKANDFSSA CMQLDPGNAI SLLDKVVGLG NILPDNLRGP LYDMAQGTVS MSEDCLYLNV FRPAGTKPGD KLPVMVWIYG GAFVFGSSAS YPGNGYVKES VEMGQPVVFV SINYRTGPYG FLGGDAITAE GNTNSGLHDQ RKGLEWVSDN IANFGGDPDK VMIFGESAGA MSVAHQLIAY GGDNTYNGKQ LFHSAILQSG GPLPYFDSTS VGPESAYSRF AQYAGCDTSV SDNDTLACLR SKSSDVLHSA QNSYDLKDLF GLLPQFLGFG PRPDGNIIPD AAYDLYRSGR YAKVPYITGN QEDEGTILAP VAINATTTPH VKKWLKYICS QASYASLDRV LSLYPGSWSE GAPFRTGILN ALTPQFKRIA AIFTDLLFQS PRRVMLNATK DVNRWTYLAT QLHNLVPFLG TFHGSDLLFQ YYVDLGPSSA YRRYFISFAN HHDPNVGTNL QQWDMYTDAG KEMLQIHMIG NSMRTDDFRI EGISNFESDV TLFG

References (10)

Title : Molecular characterization of a Galactomyces geotrichum lipase, another member of the cholinesterase\/lipase family - Phillips_1995_Biochim.Biophys.Acta_1252_305
Author(s) : Phillips A , Pretorius GH , van Rensburg HG
Ref : Biochimica & Biophysica Acta , 1252 :305 , 1995
PubMedID: 7578238
Gene_locus related to this paper: geoca-1lipa

Title : Expression and characterization of Geotrichum candidum lipase I gene. Comparison of specificity profile with lipase II - Bertolini_1995_Eur.J.Biochem_228_863
Author(s) : Bertolini MC , Schrag JD , Cygler M , Ziomek E , Thomas DY , Vernet T
Ref : European Journal of Biochemistry , 228 :863 , 1995
PubMedID: 7737187
Gene_locus related to this paper: geoca-1lipa , geoca-2lipa

Title : Polymorphism in the lipase genes of Geotrichum candidum strains - Bertolini_1994_Eur.J.Biochem_219_119
Author(s) : Bertolini MC , Laramee L , Thomas DY , Cygler M , Schrag JD , Vernet T
Ref : European Journal of Biochemistry , 219 :119 , 1994
PubMedID: 8306978
Gene_locus related to this paper: geoca-1lipa , geoca-2lipa

Title : 1.8 A refined structure of the lipase from Geotrichum candidum - Schrag_1993_J.Mol.Biol_230_575
Author(s) : Schrag JD , Cygler M
Ref : Journal of Molecular Biology , 230 :575 , 1993
PubMedID: 8464065
Gene_locus related to this paper: geoca-1lipa , geoca-2lipa

Title : Cloning and sequencing of two chromosomal lipase genes from Geotrichum candidum - Nagao_1993_J.Biochem_113_776
Author(s) : Nagao T , Shimada Y , Sugihara A , Tominaga Y
Ref : J Biochem , 113 :776 , 1993
PubMedID: 8370674
Gene_locus related to this paper: geoca-1lipa , geoca-2lipa

Title : Insights into interfacial activation from an open structure of Candida rugosa lipase - Grochulski_1993_J.Biol.Chem_268_12843
Author(s) : Grochulski P , Li Y , Schrag JD , Bouthillier F , Smith P , Harrison D , Rubin B , Cygler M
Ref : Journal of Biological Chemistry , 268 :12843 , 1993
PubMedID: 8509417
Gene_locus related to this paper: canru-1lipa , geoca-1lipa

Title : Pancreatic lipases: evolutionary intermediates in a positional change of catalytic carboxylates? - Schrag_1992_J.Biol.Chem_267_4300
Author(s) : Schrag JD , Winkler FK , Cygler M
Ref : Journal of Biological Chemistry , 267 :4300 , 1992
PubMedID: 1537823
Gene_locus related to this paper: geoca-1lipa

Title : Ser-His-Glu triad forms the catalytic site of the lipase from Geotrichum candidum - Schrag_1991_Nature_351_761
Author(s) : Schrag JD , Li YG , Wu S , Cygler M
Ref : Nature , 351 :761 , 1991
PubMedID: 2062369
Gene_locus related to this paper: geoca-1lipa

Title : Does sequence similarity of human choline esterase, Torpedo acetylcholine esterase and Geotrichum candidum lipase reveal the active site serine residue? -
Author(s) : Slabas AR , Windust J , Sidebottom CM
Ref : Biochemical Journal , 269 :279 , 1990
PubMedID: 2115773
Gene_locus related to this paper: geoca-1lipa

Title : cDNA molecular cloning of Geotrichum candidum lipase - Shimada_1989_J.Biochem_106_383
Author(s) : Shimada Y , Sugihara A , Tominaga Y , Iizumi T , Tsunasawa S
Ref : J Biochem , 106 :383 , 1989
PubMedID: 2481674
Gene_locus related to this paper: geoca-1lipa