Preussia isomera (Coprophilous fungus) (Honoratia pisana) Non-reducing polyketide synthase Orsellinate-depside hydrolase Preu6 thioesterase domain
The biosynthesis probably occurs via the formation of 2 orsellinate intermediates fused together by the C-terminal thioesterase (TE) domain that finally releases lecanoric acid. The same reaction is performed by thioesterase domain of PKS but homologous to the thoesterase family
Family : BD-FAE
Block : H
Position in NCBI Life Tree : Preussia isomera
(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Fungi N E > Dikarya N E > Ascomycota N E > saccharomyceta N E > Pezizomycotina N E > leotiomyceta N E > dothideomyceta N E > Dothideomycetes N E > Pleosporomycetidae N E > Pleosporales N E > Sporormiaceae N E > Preussia\/Sporomiella species complex N E > Preussia N E > Preussia isomera N EKTVEYKRVSG VPIHADIYVP LVQRVSPMPL ALMIHGGGHM TLSRKAVRPT QAKYLLSHGF LPISIDYRLC PEVNLIDGPI ADVRDAYVWA CQNLGTHLAE HSISVDGGRV VVVGWSTGGH LAMSLGWSLE EAGVPPPKAV LSFYAPVDFE SGELDNQKNP ALPKPRMTLD QITKALPRTP VTQYGASSTD ETNLGWLHPG DPRSELLLHV FHSDIGLPLI LHGLPISGSG RPSPSLVASI SPLARLRNGS YTIPTFIIHG TKDVIAPYAA AERFVKIMSE KGVKSGFLSL SGTGHVFDVT MKPDSKGWED KVKPGLDFLI QNA
| Title : Didepside Formation by the Nonreducing Polyketide Synthase Preu6 of Preussia isomera Requires Interaction of Starter Acyl Transferase and Thioesterase Domains - Liu_2023_Angew.Chem.Int.Ed.Engl_62_e202214379 |
| Author(s) : Liu Q , Zhang D , Gao S , Cai X , Yao M , Xu Y , Gong Y , Zheng K , Mao Y , Yang L , Yang D , Molnar I , Yang X |
| Ref : Angew Chem Int Ed Engl , 62 :e202214379 , 2023 |
| Abstract : |
| PubMedSearch : Liu_2023_Angew.Chem.Int.Ed.Engl_62_e202214379 |
| PubMedID: 36484777 |
| Gene_locus related to this paper: preis-preu6 |
| Title : Cloning and Functional Characterization of the Polyketide Synthases Based on Genome Mining of Preussia isomera XL-1326 - Liu_2022_Front.Microbiol_13_819086 |
| Author(s) : Liu Q , Zhang D , Xu Y , Gao S , Gong Y , Cai X , Yao M , Yang X |
| Ref : Front Microbiol , 13 :819086 , 2022 |
| Abstract : |
| PubMedSearch : Liu_2022_Front.Microbiol_13_819086 |
| PubMedID: 35602042 |
| Gene_locus related to this paper: preis-preu6 |