ratno-RPOP

Rattus norvegicus (Rat) Prolyl endopeptidase rPop

Comment

Relationship

Family : S9N_PPCE_Peptidase_S9

Block : X

Position in NCBI Life Tree : Rattus norvegicus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Deuterostomia N E > Chordata N E > Craniata N E > Vertebrata N E > Gnathostomata N E > Teleostomi N E > Euteleostomi N E > Sarcopterygii N E > Dipnotetrapodomorpha N E > Tetrapoda N E > Amniota N E > Mammalia N E > Theria N E > Eutheria N E > Boreoeutheria N E > Euarchontoglires N E > Glires N E > Rodentia N E > Myomorpha N E > Muroidea N E > Muridae N E > Murinae N E > Rattus N E > Rattus norvegicus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MLSFQYPDVY RDETSVQDYH GHKICDPYAW LEDPDSEQTK AFVEAQNKIT VPFLEQCPIR GLYKERMTEL YDYPKYSCHF KKGKRYFYFY NTGLQNQRVL YVQDSLEGEA RVFLDPNTLS DDGTVALRGY AFSEDGEYFA YGLSASGSDW VTIKFMKVDG AKELPDVLER VKFTCMAWTH DGKGMFYNSY PQQDGKSDGT ETSTNLHQKL CYHVLGTDQS EDVLCAEFPD EPKWMGGAEL SDDGRYVLLS IWEGCDPVNR LWYCDLQQGS NGINGILKWV KLIDNFEGEY DYITNEGTVF TFKTNRNSPN YRLINIDFTD PDESKWKVLV PEHEKDVLEW VACVRSNFLV LCYLRNVKNI LQLHDLTTGA LLKTFPLDVG SVVGYSGRKK DSEIFYQFTS FLSPGVIYHC DLTREELEPR VFREVTVKGI DASDYQTIQV FYPSKDGTKI PMFIVHKKGI KLDGSHPAFL YGYGGFNISI TPNYSVSRLI FVRHMGGVLA VANIRGGGEY GETWHKGGIL ANKQNCFDDF QCAAEYLIKE GYTTSKRLTI NGGSNGGLLV AACANQRPDL FGCVIAQVGV MDMLKFHKFT IGHAWTTDYG CSDSKQHFEW LLKYSPLHNV KLPEADDIQY PSMLLLTADH DDRVVPLHSL KFIATLQYIV GRSRKQSNPL LIHVDTKAGH GPGKPTAKVI EEVSDMFAFI ARCLNIEWIQ

References (4)

Title : Prolyl oligopeptidase inhibition decreases extracellular acetylcholine levels in rat hippocampus and prefrontal cortex - Jalkanen_2014_Neurosci.Lett_579_110
Author(s) : Jalkanen AJ , Leikas JV , Forsberg MM
Ref : Neuroscience Letters , 579 :110 , 2014
Abstract :
PubMedSearch : Jalkanen_2014_Neurosci.Lett_579_110
PubMedID: 25064702
Gene_locus related to this paper: ratno-RPOP

Title : Brain pharmacokinetics of two prolyl oligopeptidase inhibitors, JTP-4819 and KYP-2047, in the rat - Jalkanen_2011_Basic.Clin.Pharmacol.Toxicol_109_443
Author(s) : Jalkanen AJ , Hakkarainen JJ , Lehtonen M , Venalainen T , Kaariainen TM , Jarho E , Suhonen M , Forsberg MM
Ref : Basic Clin Pharmacol Toxicol , 109 :443 , 2011
Abstract :
PubMedSearch : Jalkanen_2011_Basic.Clin.Pharmacol.Toxicol_109_443
PubMedID: 21707925
Gene_locus related to this paper: human-PREP , ratno-RPOP

Title : Beneficial effect of prolyl oligopeptidase inhibition on spatial memory in young but not in old scopolamine-treated rats - Jalkanen_2007_Basic.Clin.Pharmacol.Toxicol_100_132
Author(s) : Jalkanen AJ , Puttonen KA , Venalainen JI , Sinerva V , Mannila A , Ruotsalainen S , Jarho EM , Wallen EA , Mannisto PT
Ref : Basic Clin Pharmacol Toxicol , 100 :132 , 2007
Abstract :
PubMedSearch : Jalkanen_2007_Basic.Clin.Pharmacol.Toxicol_100_132
PubMedID: 17244263
Gene_locus related to this paper: ratno-RPOP

Title : cDNA cloning of rat prolyl oligopeptidase and its expression in the ovary during the estrous cycle - Kimura_2000_J.Exp.Zool_286_656
Author(s) : Kimura A , Takahashi T
Ref : Journal of Experimental Zoology , 286 :656 , 2000
Abstract :
PubMedSearch : Kimura_2000_J.Exp.Zool_286_656
PubMedID: 10766975
Gene_locus related to this paper: ratno-RPOP