Gene_locus Report for: 9firm-a0a0r2h5m0

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)
> cellular organisms: N E > Bacteria: N E > Terrabacteria group: N E > Firmicutes: N E > Erysipelotrichia: N E > Erysipelotrichales: N E > Erysipelotrichaceae: N E > Kandleria: N E > Kandleria vitulina: N E > Kandleria vitulina DSM 20405: N E

Title: Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera
Sun Z, Harris HM, McCann A, Guo C, Argimon S, Zhang W, Yang X, Jeffery IB, Cooney JC and O'Toole PW <21 more author(s)> Sun Z, Harris HM, McCann A, Guo C, Argimon S, Zhang W, Yang X, Jeffery IB, Cooney JC, Kagawa TF, Liu W, Song Y, Salvetti E, Wrobel A, Rasinkangas P, Parkhill J, Rea MC, O'Sullivan O, Ritari J, Douillard FP, Paul Ross R, Yang R, Briner AE, Felis GE, de Vos WM, Barrangou R, Klaenhammer TR, Caufield PW, Cui Y, Zhang H, O'Toole PW (- 21)
Ref: Nat Commun, 6:8322, 2015 : PubMed
Abstract


ESTHER: Sun_2015_Nat.Commun_6_8322
PubMedSearch: Sun 2015 Nat.Commun 6 8322
PubMedID: 26415554
Gene_locus related to this paper: 9laco-a0a0r1hz65, 9laco-a0a0r1j1t4, 9laco-a0a0r1j3p0, 9laco-a0a0r1k3i0, 9laco-a0a0r1k563, 9laco-a0a0r1kgb3, 9laco-a0a0r1kji2, 9laco-a0a0r1kwq5, 9laco-a0a0r1l700, 9laco-a0a0r1p6l8, 9laco-a0a0r1q939, 9laco-a0a0r1qv39, 9laco-a0a0r1wj75, laccl-a0a0r2bne3, 9laco-a0a0r2dnk9, 9laco-a0a0r2ds70, 9laco-a0a0r2k127, 9laco-a0a0r2lee7, 9laco-a0a0r2lqt2, 9laco-a0a0r2m354, 9laco-a0a0r2n9f2, 9laco-a0a0r2nrk2, lacze-a0a0r1ekw6, 9laco-a0a0r1ju11, 9laco-a0a0r1k516, 9laco-a0a0r1leq9, 9laco-a0a0r1lul8, 9laco-a0a0r1lzg4, 9laco-a0a0r1mhp8, 9laco-a0a0r1mjt1, 9laco-a0a0r1nv21, 9laco-a0a0r1q1p6, 9laco-a0a0r1qm41, 9laco-a0a0r1qs58, 9laco-a0a0r1rgu0, 9laco-a0a0r1tg12, 9laco-a0a0r1u777, 9laco-a0a0r1ufv3, 9laco-a0a0r1ul77, 9laco-a0a0r1vad0, 9laco-a0a0r1w3f4, 9laco-a0a0r1w9r8, 9laco-a0a0r1wpq2, 9laco-a0a0r1x2g3, 9laco-a0a0r2abe6, 9laco-a0a0r2b6w1, 9laco-a0a0r2b8g1, 9laco-a0a0r2ch10, 9laco-a0a0r2cld6, 9laco-a0a0r2cv38, 9laco-a0a0r2d3x3, 9laco-a0a0r2dct2, 9laco-a0a0r2flt3, 9laco-a0a0r2frk5, 9laco-a0a0r2guq4, 9firm-a0a0r2h5m0, weivi-a0a0r2h8r4, 9lact-a0a0r2hnx4, 9lact-a0a0r2jkt6, 9lact-a0a0r2jmz1, 9laco-a0a0r2jwg5, 9laco-a0a0r2jxu0, 9laco-a0a0r2jxw0, lacam-a0a0r2kgt3, 9laco-a0a0r2kx86, 9laco-a0a0r2mxi6, 9laco-a0a0r1vln2, 9laco-a0a0r2ca25, 9laco-a0a0r1zjs2, weipa-c5rbw8

Abstract

Lactobacilli are a diverse group of species that occupy diverse nutrient-rich niches associated with humans, animals, plants and food. They are used widely in biotechnology and food preservation, and are being explored as therapeutics. Exploiting lactobacilli has been complicated by metabolic diversity, unclear species identity and uncertain relationships between them and other commercially important lactic acid bacteria. The capacity for biotransformations catalysed by lactobacilli is an untapped biotechnology resource. Here we report the genome sequences of 213 Lactobacillus strains and associated genera, and their encoded genetic catalogue for modifying carbohydrates and proteins. In addition, we describe broad and diverse presence of novel CRISPR-Cas immune systems in lactobacilli that may be exploited for genome editing. We rationalize the phylogenomic distribution of host interaction factors and bacteriocins that affect their natural and industrial environments, and mechanisms to withstand stress during technological processes. We present a robust phylogenomic framework of existing species and for classifying new species.