gasac-nlgn2b

 
Gasterosteus aculeatus (Three-spined stickleback) Neuroligin 2b

Relationship
Family Neuroligin
Block C
Gasterosteus aculeatus position in NCBI Life Tree :
N link to NCBI taxonomic web page and E link to ESTHER gene locus found in this strain.
> cellular organisms: N E > Eukaryota: N E > Opisthokonta: N E > Metazoa: N E > Eumetazoa: N E > Bilateria: N E > Deuterostomia: N E > Chordata: N E > Craniata: N E > Vertebrata: N E > Gnathostomata: N E > Teleostomi: N E > Euteleostomi: N E > Actinopterygii: N E > Actinopteri: N E > Neopterygii: N E > Teleostei: N E > Osteoglossocephalai: N E > Clupeocephala: N E > Euteleosteomorpha: N E > Neoteleostei: N E > Eurypterygia: N E > Ctenosquamata: N E > Acanthomorphata: N E > Euacanthomorphacea: N E > Percomorphaceae: N E > Eupercaria: N E > Perciformes: N E > Cottioidei: N E > Gasterosteales: N E > Gasterosteidae: N E > Gasterosteus: N E > Gasterosteus aculeatus: N E

Molecular evidence
Database
No mutation
No structure
No kinetic



1 Genbank : GQ489223
3 UniProt : D2X2J2, G3QAD4, G3QAD5
3 UniProtTrembl : D2X2J2, G3QAD4, G3QAD5
3 Interpro : D2X2J2, G3QAD4, G3QAD5
3 Prodom : D2X2J2, G3QAD4, G3QAD5
3 Pfam : D2X2J2, G3QAD4, G3QAD5
3 PIRSF : D2X2J2, G3QAD4, G3QAD5
3 SUPERFAM : D2X2J2, G3QAD4, G3QAD5
3 QuickSwissBlast : D2X2J2, G3QAD4, G3QAD5
 
Sequence
Graphical view for this peptide sequence: gasac-nlgn2b
Colored MSA for Neuroligin (raw)
MTKRAFILDMLFFPLNAASHHGYGGKRHYNSQQIANHCLLWLLGLVLHLT
LSSCQRVDLKHPIVSTGYGKIRGIKKDLNNEILGPVEQYLGVPYATAPVG
ERRFQPPEAPGSWQEIRNATQFAPVCPQNVHGVLPEIMLPVWFTDNLDAA
ATYVQNQSEDCLYLNIYVPTEDGPLTKKQDESTMNRPRDEDIRDRRKKPV
MLFIHGGSYMEGSGNLFDGSVLAAYGNVIVVTMNYRLGVLGFLSTGDQSA
KGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGAACVNLLILSHH
SEGLFQRAIAQSGSAISSWAVNYRPTMYTKILAKKVGCTLGDMADLVECL
RRKSFRELVDQDIQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDIL
LGVNQGEGLKFVDDSEGEDEISASSFDYTISNFVDNLYGYPDGKDILRET
IKFMYTDWADRDNSDMRRKTLLALFTDHQWVAPAVATAKLHAEFQSPVYF
YTFHHHCQTEARPEWADAAHGDEIPYVFGIPMVGATDLFPCNFSKNDVML
SAVVMTYWTNFAKTGDPNLPVPQDTTFIHTKPNRFEEVIWTKFSSKDKQY
LHIGLKPRVRDNYRANKVAFWLELVPHLHSLHKEIISSITTRLPPGGPNR
WKGPPSPGTRSTRHPVISTYAPDPEPYGSERPRFSPFPDETRDYSTELSV
TVAVGASLLFLNMLAFAALYYKRDKRHELMQRRHRRLSPQRVTTMGMGMG
VGMGVVGSPPHNDLALSQEEELMSLQMKQQRVELEHGTPLPSRGVHGDLE
PLRPPVCPPDYTLALRRAPEDVPLMTANTITMIPSTISSMQPLHPFNTYP
PVPAPSTTPVPSHSNNALPHQHSTTRV
Legend This sequence has been compared to family alignement (MSA)
red => minority aminoacid
blue => majority aminoacid
color intensity => conservation rate
title => sequence position(MSA position)aminoacid rate
Catalytic site
Catalytic site in the MSA

MTKRAFILDMLFFPLNAASHHGYGGKRHYNSQQIANHCLLWLLGLVLHLT
LSSCQRVDLKHPIVSTGYGKIRGIKKDLNNEILGPVEQYLGVPYATAPVG
ERRFQPPEAPGSWQEIRNATQFAPVCPQNVHGVLPEIMLPVWFTDNLDAA
ATYVQNQSEDCLYLNIYVPTEDGPLTKKQDESTMNRPRDEDIRDRRKKPV
MLFIHGGSYMEGSGNLFDGSVLAAYGNVIVVTMNYRLGVLGFLSTGDQSA
KGNYGLLDQIQALRWLNENIGHFGGDPERITIFGSGAGAACVNLLILSHH
SEGLFQRAIAQSGSAISSWAVNYRPTMYTKILAKKVGCTLGDMADLVECL
RRKSFRELVDQDIQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDIL
LGVNQGEGLKFVDDSEGEDEISASSFDYTISNFVDNLYGYPDGKDILRET
IKFMYTDWADRDNSDMRRKTLLALFTDHQWVAPAVATAKLHAEFQSPVYF
YTFHHHCQTEARPEWADAAHGDEIPYVFGIPMVGATDLFPCNFSKNDVML
SAVVMTYWTNFAKTGDPNLPVPQDTTFIHTKPNRFEEVIWTKFSSKDKQY
LHIGLKPRVRDNYRANKVAFWLELVPHLHSLHKEIISSITTRLPPGGPNR
WKGPPSPGTRSTRHPVISTYAPDPEPYGSERPRFSPFPDETRDYSTELSV
TVAVGASLLFLNMLAFAALYYKRDKRHELMQRRHRRLSPQRVTTMGMGMG
VGMGVVGSPPHNDLALSQEEELMSLQMKQQRVELEHGTPLPSRGVHGDLE
PLRPPVCPPDYTLALRRAPEDVPLMTANTITMIPSTISSMQPLHPFNTYP
PVPAPSTTPVPSHSNNALPHQHSTTRV

no DNA




Reference
    Title: Characterization of the neuroligin gene family expression and evolution in zebrafish
    Rissone A, Sangiorgio L, Monopoli M, Beltrame M, Zucchi I, Bussolino F, Arese M, Cotelli F
    Ref: Developmental Dynamics, 239:688, 2010 : PubMed

            


Other Papers


Send your questions or comments to :
Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
For technical information about these pages see:
ESTHER Home Page and ACEDB Home Page
AcePerl Lincoln Stein Home Page
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