Benzylpiperidin-carbamoylphenyl-chlorobenzamide-Cpd6b
AChE IC50 = 0.14 +/- 0.03 nM
General
Type : Piperidine, Benzylpiperidine, Derivative of Donepezil, Carboxamide, Organochlorine
Chemical_Nomenclature : N-(4-(1-Benzylpiperidin-4-yl)carbamoylphenyl)-3-chlorobenzamide
Canonical SMILES : C1=CC=CC(=C1)CN2CCC(CC2)NC(C3=CC=C(C=C3)NC(C4=CC=CC(=C4)Cl)=O)=O
InChI : InChI=1S\/C26H26ClN3O2\/c27-22-8-4-7-21(17-22)26(32)28-23-11-9-20(10-12-23)25(31)29-24-13-15-30(16-14-24)18-19-5-2-1-3-6-19\/h1-12,17,24H,13-16,18H2,(H,28,32)(H,29,31)
InChIKey : BGBBHNUWRLQUOJ-UHFFFAOYSA-N
Other name(s) : Compound 6b
Target
Families : Benzylpiperidin-carbamoylphenyl-chlorobenzamide-Cpd6b ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Novel acetylcholinesterase inhibitors: synthesis, docking and inhibitory activity evaluation of 4-benzamido-N-(1-benzylpiperidin-4-yl) benzamide derivatives - Mohammadi-Farani_2024_Results.Chem_7_101273 |
| Author(s) : Mohammadi-Farani A , Nazari S , Mohammadi M , Jamshidy Navid S , Hosseini A , Aliabadi A |
| Ref : Results in Chemistry , 7 :101273 , 2024 |
| Abstract : |
| PubMedSearch : Mohammadi-Farani_2024_Results.Chem_7_101273 |
| PubMedID: |