Benzylpiperidine

Inhibitor	Main targeted enzyme families	Type	Structure
Benzylpiperidin-dimethylamino-hydroxyphenyl-pyridazin-one-Cpd7a	ACHE	Pyridazine Piperidine anti-Abeta-aggregation Multitarget Benzylpiperidine Derivative of Donepezil
CD05692	BCHE	Piperidine Cyanide Benzylpiperidine Derivative of Donepezil
CHEMBL5647316-11a		Pyrimidine Phosphodiesterase-IN Multitarget Piperidine Pyrazole Benzylpiperidine Derivative of Donepezil
CHEMBL4085222	BCHE	Derivative of Donepezil Piperidine Quinoline Feruloyl Isoquinoline Benzylpiperidine
Deriv-CHEMBL4085222-Cpd8e	BCHE	Feruloyl Derivative of Donepezil Piperidine Quinoline Benzylpiperidine
Benzylpiperidine-isatin-Cpd15	ACHE	Monoamine-oxidase-inhibitor Multitarget Piperidine Isatin Alkyne Benzylpiperidine Derivative of Donepezil Organochlorine
CHEMBL4595876	ACHE	Multitarget Pyridine Sigma1R ligand Cyanide Alkyne Benzylpiperidine Derivative of Donepezil
SCHEMBL21061872	Monoglyceridelipase_lysophospholip	Benzoxazine Oxazine Piperidine Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-methylene-methoxy-dihydro-inden-one	ACHE	Inden BACE1-inhibitor Derivative of Donepezil Multitarget Piperidine Benzylpiperidine
lipoicacid-donepezil-cpd5	ACHE BCHE	Multitarget Sulfur Compound Alkyl linked bis-ligand Benzylpiperidine Derivative of Donepezil
Colchicine-donepezil-SBN-284-3x	ACHE BCHE	Multitarget Benzylpiperidine Derivative of Donepezil Piperidine NLRP3 inflammasome activation
ADS031	ACHE	Histamine-Receptor3-H3-Antagonist Multitarget Piperidine Naphthalen Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-methylsulfonyl-indol-acryloyl-phenyl-acetamide-cpd6b	BCHE ACHE	Multitarget Indole Carboxamide Piperidine Sulfur Compound Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-oxoindolin-acetamide-Cpd23	ACHE	Piperidine Indole Benzylpiperidine Derivative of Donepezil
Indole-piperidine-amide-cpd23a	ACHE	Multitarget Indole Carboxamide Derivative of Donepezil BACE1-inhibitor Piperidine Benzylpiperidine
J8-A34	ACHE	Piperidine Sulfur Compound Sulfonamide Quinoline Isoquinoline Cyclobutyl Benzylpiperidine Derivative of Donepezil Organochlorine
Compound5d-Benzylpiperidine-Phenyl-oxadiazol-thiol	ACHE	anti-Abeta-aggregation Sulfur Compound BACE1-inhibitor Piperidine Multitarget Carboxamide Oxadiazol Derivative of Donepezil Cyanide Benzylpiperidine
WMY90-5f	ACHE	Quinoline Multitarget Monoamine-oxidase-inhibitor Alkyne Cyanide Benzylpiperidine Derivative of Donepezil
DPH6	BCHE ACHE	Quinoline Multitarget Monoamine-oxidase-inhibitor Alkyne Cyanide Benzylpiperidine Derivative of Donepezil
DFAH-12	BCHE ACHE	Piperidine Hydroxycinnamic-ester Multitarget Antioxidant Benzylpiperidine Derivative of Donepezil Organochlorine
Benzyl-piperidine-4-ethyl-phthalimide-6c	ACHE	Isoindole Piperidine Indole Benzylpiperidine Derivative of Donepezil
7QB4-Cpd2	ACHE	Monoamine-oxidase-inhibitor Multitarget Coumarin Chromen Benzylpiperidine Derivative of Donepezil
ABC44	Palmitoyl-protein_thioesterase	Carbamate Piperidine N-hydroxyhydantoin Benzylpiperidine Derivative of Donepezil
KT203	ABHD6-Lip	Piperidine Triazol Benzylpiperidine
SCHEMBL24135488	ACHE BCHE	Multitarget Calcium Channel Antagonist anti-Abeta-aggregation Derivative of Donepezil Histamine-Receptor3-H3-Antagonist Benzylpiperidine
BIGI-3h	ACHE BCHE	Multitarget Monoamine-oxidase-inhibitor GSK-3 kinase inhibitor Calcium Channel Antagonist anti-Abeta-aggregation Benzylpiperidine Derivative of Donepezil Organochlorine
6RUA-3a	BCHE	Sulfur Compound Sulfonamide Coumarin Piperidine Carboxamide Naphthalen Chromen Benzylpiperidine Derivative of Donepezil
JUB	BCHE	Piperidine Piperazine NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole Sulfur Compound Sulfonamide Naphthalen Benzylpiperidine Derivative of Donepezil
Compound-183	abh_upf0017	Piperidine Benzylpiperidine
Salicylic-donepezil-rivastigmine-5a	BCHE	Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
5DYT-5hb	BCHE	Piperidine Benzylpiperidine Derivative of Donepezil Sulfonamide Sulfur Compound Naphthalen
5DYY-5hh	BCHE	Piperidine Sulfonamide Sulfur Compound Naphthalen Benzylpiperidine Derivative of Donepezil
CHEMBL4293015	BCHE	Indole Piperidine Alkyl linked bis-ligand Benzylpiperidine Derivative of Donepezil
ASS234	ACHE	Multitarget Monoamine-oxidase-inhibitor Alkyl linked bis-ligand Piperidine Indole Alkyne Benzylpiperidine Derivative of Donepezil
CHEMBL4105611	BCHE	Piperidine Sulfur Compound Sulfonamide PET probe Naphthalen Benzylpiperidine Derivative of Donepezil
Tacrine-Donepezil-hybrid3	ACHE	Derivative of Tacrine Acridine Benzylpiperidine Derivative of Donepezil
Mebbpp	ACHE	Multitarget Sulfur Compound Piperidine Benzylpiperidine Derivative of Donepezil
Donepezil-Melatonin-4u	ACHE	Derivative of Tryptamine Indole Alkyl linked bis-ligand Multitarget Antioxidant Benzylpiperidine Derivative of Donepezil
Selenepezil	ACHE	Organoselenium Thiol-reactive Piperidine Benzylpiperidine Derivative of Donepezil
MGL-Inhibitor-26	Monoglyceridelipase_lysophospholip	Piperidine Carboxamide Pyrazole Benzylpiperidine Derivative of Donepezil
KT172	Lipase_3 Carb_B_Chordata ABHD6-Lip	Piperidine Biphenyl Triazol Benzylpiperidine
KT109	Lipase_3 Carb_B_Chordata ABHD6-Lip abh_upf0017	Piperidine Biphenyl Triazol Benzylpiperidine
T-82(1)	ACHE	Piperidine Quinoline Benzylpiperidine Derivative of Donepezil
Aricept~Donepezil~E2020	ACHE	Derivative of Donepezil Piperidine Drug Benzylpiperidine Inden Organochlorine
N-benzylpiperidine-carbazol-9c	BCHE	Piperidine Carbazol beta-carboline Derivative of Donepezil Multitarget Benzylpiperidine
TAK-147	ACHE	Piperidine Transition state analogue Benzazepin Benzylpiperidine Derivative of Donepezil
Icopezil	ACHE	Piperidine Benzoxazol Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-dimethylamino-hydroxyphenyl-pyridazin-one-Cpd7a	ACHE	Pyridazine Piperidine anti-Abeta-aggregation Multitarget Benzylpiperidine Derivative of Donepezil
CD05692	BCHE	Piperidine Cyanide Benzylpiperidine Derivative of Donepezil
CHEMBL5647316-11a		Pyrimidine Phosphodiesterase-IN Multitarget Piperidine Pyrazole Benzylpiperidine Derivative of Donepezil
CHEMBL4085222	BCHE	Derivative of Donepezil Piperidine Quinoline Feruloyl Isoquinoline Benzylpiperidine
Deriv-CHEMBL4085222-Cpd8e	BCHE	Feruloyl Derivative of Donepezil Piperidine Quinoline Benzylpiperidine
Benzylpiperidine-isatin-Cpd15	ACHE	Monoamine-oxidase-inhibitor Multitarget Piperidine Isatin Alkyne Benzylpiperidine Derivative of Donepezil Organochlorine
CHEMBL4595876	ACHE	Multitarget Pyridine Sigma1R ligand Cyanide Alkyne Benzylpiperidine Derivative of Donepezil
SCHEMBL21061872	Monoglyceridelipase_lysophospholip	Benzoxazine Oxazine Piperidine Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-methylene-methoxy-dihydro-inden-one	ACHE	Inden BACE1-inhibitor Derivative of Donepezil Multitarget Piperidine Benzylpiperidine
lipoicacid-donepezil-cpd5	ACHE BCHE	Multitarget Sulfur compound Alkyl linked bis-ligand Benzylpiperidine Derivative of Donepezil
Colchicine-donepezil-SBN-284-3x	ACHE BCHE	Multitarget Benzylpiperidine Derivative of Donepezil Piperidine NLRP3 inflammasome activation
ADS031	ACHE	Histamine-Receptor3-H3-Antagonist Multitarget Piperidine Naphthalen Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-methylsulfonyl-indol-acryloyl-phenyl-acetamide-cpd6b	BCHE ACHE	Multitarget Indole Carboxamide Piperidine Sulfur compound Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-oxoindolin-acetamide-Cpd23	ACHE	Piperidine Indole Benzylpiperidine Derivative of Donepezil
Indole-piperidine-amide-cpd23a	ACHE	Multitarget Indole Carboxamide Derivative of Donepezil BACE1-inhibitor Piperidine Benzylpiperidine
J8-A34	ACHE	Piperidine Sulfur compound Sulfonamide Quinoline Isoquinoline Cyclobutyl Benzylpiperidine Derivative of Donepezil Organochlorine
Compound5d-Benzylpiperidine-Phenyl-oxadiazol-thiol	ACHE	anti-Abeta-aggregation Sulfur compound BACE1-inhibitor Piperidine Multitarget Carboxamide Oxadiazol Derivative of Donepezil Cyanide Benzylpiperidine
WMY90-5f	ACHE	Quinoline Multitarget Monoamine-oxidase-inhibitor Alkyne Cyanide Benzylpiperidine Derivative of Donepezil
DPH6	BCHE ACHE	Quinoline Multitarget Monoamine-oxidase-inhibitor Alkyne Cyanide Benzylpiperidine Derivative of Donepezil
DFAH-12	BCHE ACHE	Piperidine Hydroxycinnamic-ester Multitarget Antioxidant Benzylpiperidine Derivative of Donepezil Organochlorine
Benzyl-piperidine-4-ethyl-phthalimide-6c	ACHE	Isoindole Piperidine Indole Benzylpiperidine Derivative of Donepezil
7QB4-Cpd2	ACHE	Monoamine-oxidase-inhibitor Multitarget Coumarin Chromen Benzylpiperidine Derivative of Donepezil
ABC44	Palmitoyl-protein_thioesterase	Carbamate Piperidine N-hydroxyhydantoin Benzylpiperidine Derivative of Donepezil
KT203	ABHD6-Lip	Piperidine Triazol Benzylpiperidine
SCHEMBL24135488	ACHE BCHE	Multitarget Calcium Channel Antagonist anti-Abeta-aggregation Derivative of Donepezil Histamine-Receptor3-H3-Antagonist Benzylpiperidine
BIGI-3h	ACHE BCHE	Multitarget Monoamine-oxidase-inhibitor GSK-3 kinase inhibitor Calcium Channel Antagonist anti-Abeta-aggregation Benzylpiperidine Derivative of Donepezil Organochlorine
6RUA-3a	BCHE	Sulfur compound Sulfonamide Coumarin Piperidine Carboxamide Naphthalen Chromen Benzylpiperidine Derivative of Donepezil
JUB	BCHE	Piperidine Piperazine NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole Sulfur compound Sulfonamide Naphthalen Benzylpiperidine Derivative of Donepezil
Compound-183	abh_upf0017	Piperidine Benzylpiperidine
Salicylic-donepezil-rivastigmine-5a	BCHE	Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
5DYT-5hb	BCHE	Piperidine Benzylpiperidine Derivative of Donepezil Sulfonamide Sulfur compound Naphthalen
5DYY-5hh	BCHE	Piperidine Sulfonamide Sulfur compound Naphthalen Benzylpiperidine Derivative of Donepezil
CHEMBL4293015	BCHE	Indole Piperidine Alkyl linked bis-ligand Benzylpiperidine Derivative of Donepezil
ASS234	ACHE	Multitarget Monoamine-oxidase-inhibitor Alkyl linked bis-ligand Piperidine Indole Alkyne Benzylpiperidine Derivative of Donepezil
CHEMBL4105611	BCHE	Piperidine Sulfur compound Sulfonamide PET probe Naphthalen Benzylpiperidine Derivative of Donepezil
Tacrine-Donepezil-hybrid3	ACHE	Derivative of Tacrine Acridine Benzylpiperidine Derivative of Donepezil
Mebbpp	ACHE	Multitarget Sulfur compound Piperidine Benzylpiperidine Derivative of Donepezil
Donepezil-Melatonin-4u	ACHE	Derivative of Tryptamine Indole Alkyl linked bis-ligand Multitarget Antioxidant Benzylpiperidine Derivative of Donepezil
Selenepezil	ACHE	Organoselenium Thiol-reactive Piperidine Benzylpiperidine Derivative of Donepezil
MGL-Inhibitor-26	Monoglyceridelipase_lysophospholip	Piperidine Carboxamide Pyrazole Benzylpiperidine Derivative of Donepezil
KT172	Lipase_3 Carb_B_Chordata ABHD6-Lip	Piperidine Biphenyl Triazol Benzylpiperidine
KT109	Lipase_3 Carb_B_Chordata ABHD6-Lip abh_upf0017	Piperidine Biphenyl Triazol Benzylpiperidine
T-82(1)	ACHE	Piperidine Quinoline Benzylpiperidine Derivative of Donepezil
Aricept~Donepezil~E2020	ACHE	Derivative of Donepezil Piperidine Drug Benzylpiperidine Inden Organochlorine
N-benzylpiperidine-carbazol-9c	BCHE	Piperidine Carbazol beta-carboline Derivative of Donepezil Multitarget Benzylpiperidine
TAK-147	ACHE	Piperidine Transition state analogue Benzazepin Benzylpiperidine Derivative of Donepezil
Icopezil	ACHE	Piperidine Benzoxazol Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-dimethylamino-hydroxyphenyl-pyridazin-one-Cpd7a	ACHE	Pyridazine Piperidine anti-Abeta-aggregation Multitarget Benzylpiperidine Derivative of Donepezil
CD05692	BCHE	Piperidine Cyanide Benzylpiperidine Derivative of Donepezil
CHEMBL5647316-11a		Pyrimidine Phosphodiesterase-IN Multitarget Piperidine Pyrazole Benzylpiperidine Derivative of Donepezil
CHEMBL4085222	BCHE	Derivative of Donepezil Piperidine Quinoline Feruloyl Isoquinoline Benzylpiperidine
Deriv-CHEMBL4085222-Cpd8e	BCHE	Feruloyl Derivative of Donepezil Piperidine Quinoline Benzylpiperidine
Benzylpiperidine-isatin-Cpd15	ACHE	Monoamine-oxidase-inhibitor Multitarget Piperidine Isatin Alkyne Benzylpiperidine Derivative of Donepezil Organochlorine
CHEMBL4595876	ACHE	Multitarget Pyridine Sigma1R ligand Cyanide Alkyne Benzylpiperidine Derivative of Donepezil
SCHEMBL21061872	Monoglyceridelipase_lysophospholip	Benzoxazine Oxazine Piperidine Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-methylene-methoxy-dihydro-inden-one	ACHE	Inden BACE1-inhibitor Derivative of Donepezil Multitarget Piperidine Benzylpiperidine
lipoicacid-donepezil-cpd5	ACHE BCHE	Multitarget Sulfur compound Alkyl linked bis-ligand Benzylpiperidine Derivative of Donepezil
Colchicine-donepezil-SBN-284-3x	ACHE BCHE	Multitarget Benzylpiperidine Derivative of Donepezil Piperidine NLRP3 inflammasome activation
ADS031	ACHE	Histamine-Receptor3-H3-Antagonist Multitarget Piperidine Naphthalen Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-methylsulfonyl-indol-acryloyl-phenyl-acetamide-cpd6b	BCHE ACHE	Multitarget Indole Carboxamide Piperidine Sulfur compound Benzylpiperidine Derivative of Donepezil
Benzylpiperidin-oxoindolin-acetamide-Cpd23	ACHE	Piperidine Indole Benzylpiperidine Derivative of Donepezil
Indole-piperidine-amide-cpd23a	ACHE	Multitarget Indole Carboxamide Derivative of Donepezil BACE1-inhibitor Piperidine Benzylpiperidine
J8-A34	ACHE	Piperidine Sulfur compound Sulfonamide Quinoline Isoquinoline Cyclobutyl Benzylpiperidine Derivative of Donepezil Organochlorine
Compound5d-Benzylpiperidine-Phenyl-oxadiazol-thiol	ACHE	anti-Abeta-aggregation Sulfur compound BACE1-inhibitor Piperidine Multitarget Carboxamide Oxadiazol Derivative of Donepezil Cyanide Benzylpiperidine
WMY90-5f	ACHE	Quinoline Multitarget Monoamine-oxidase-inhibitor Alkyne Cyanide Benzylpiperidine Derivative of Donepezil
DPH6	BCHE ACHE	Quinoline Multitarget Monoamine-oxidase-inhibitor Alkyne Cyanide Benzylpiperidine Derivative of Donepezil
DFAH-12	BCHE ACHE	Piperidine Hydroxycinnamic-ester Multitarget Antioxidant Benzylpiperidine Derivative of Donepezil Organochlorine
Benzyl-piperidine-4-ethyl-phthalimide-6c	ACHE	Isoindole Piperidine Indole Benzylpiperidine Derivative of Donepezil
7QB4-Cpd2	ACHE	Monoamine-oxidase-inhibitor Multitarget Coumarin Chromen Benzylpiperidine Derivative of Donepezil
ABC44	Palmitoyl-protein_thioesterase	Carbamate Piperidine N-hydroxyhydantoin Benzylpiperidine Derivative of Donepezil
KT203	ABHD6-Lip	Piperidine Triazol Benzylpiperidine
SCHEMBL24135488	ACHE BCHE	Multitarget Calcium Channel Antagonist anti-Abeta-aggregation Derivative of Donepezil Histamine-Receptor3-H3-Antagonist Benzylpiperidine
BIGI-3h	ACHE BCHE	Multitarget Monoamine-oxidase-inhibitor GSK-3 kinase inhibitor Calcium Channel Antagonist anti-Abeta-aggregation Benzylpiperidine Derivative of Donepezil Organochlorine
6RUA-3a	BCHE	Sulfur compound Sulfonamide Coumarin Piperidine Carboxamide Naphthalen Chromen Benzylpiperidine Derivative of Donepezil
JUB	BCHE	Piperidine Piperazine NBD-nitro-benzoxadiazol-fluorescent Benzoxadiazole Sulfur compound Sulfonamide Naphthalen Benzylpiperidine Derivative of Donepezil
Compound-183	abh_upf0017	Piperidine Benzylpiperidine
Salicylic-donepezil-rivastigmine-5a	BCHE	Carbamate Derivative of Donepezil Salicylic Derivative of Rivastigmine Stigmine Benzylpiperidine
5DYT-5hb	BCHE	Piperidine Benzylpiperidine Derivative of Donepezil Sulfonamide Sulfur compound Naphthalen
5DYY-5hh	BCHE	Piperidine Sulfonamide Sulfur compound Naphthalen Benzylpiperidine Derivative of Donepezil
CHEMBL4293015	BCHE	Indole Piperidine Alkyl linked bis-ligand Benzylpiperidine Derivative of Donepezil
ASS234	ACHE	Multitarget Monoamine-oxidase-inhibitor Alkyl linked bis-ligand Piperidine Indole Alkyne Benzylpiperidine Derivative of Donepezil
CHEMBL4105611	BCHE	Piperidine Sulfur compound Sulfonamide PET probe Naphthalen Benzylpiperidine Derivative of Donepezil
Tacrine-Donepezil-hybrid3	ACHE	Derivative of Tacrine Acridine Benzylpiperidine Derivative of Donepezil
Mebbpp	ACHE	Multitarget Sulfur compound Piperidine Benzylpiperidine Derivative of Donepezil
Donepezil-Melatonin-4u	ACHE	Derivative of Tryptamine Indole Alkyl linked bis-ligand Multitarget Antioxidant Benzylpiperidine Derivative of Donepezil
Selenepezil	ACHE	Organoselenium Thiol-reactive Piperidine Benzylpiperidine Derivative of Donepezil
MGL-Inhibitor-26	Monoglyceridelipase_lysophospholip	Piperidine Carboxamide Pyrazole Benzylpiperidine Derivative of Donepezil
KT172	Lipase_3 Carb_B_Chordata ABHD6-Lip	Piperidine Biphenyl Triazol Benzylpiperidine
KT109	Lipase_3 Carb_B_Chordata ABHD6-Lip abh_upf0017	Piperidine Biphenyl Triazol Benzylpiperidine
T-82(1)	ACHE	Piperidine Quinoline Benzylpiperidine Derivative of Donepezil
Aricept~Donepezil~E2020	ACHE	Derivative of Donepezil Piperidine Drug Benzylpiperidine Inden Organochlorine
N-benzylpiperidine-carbazol-9c	BCHE	Piperidine Carbazol beta-carboline Derivative of Donepezil Multitarget Benzylpiperidine
TAK-147	ACHE	Piperidine Transition state analogue Benzazepin Benzylpiperidine Derivative of Donepezil
Icopezil	ACHE	Piperidine Benzoxazol Benzylpiperidine Derivative of Donepezil