Diazepine-carbamate-cpd6b
IC50 value of 32 +/- 25 nM for BChE
General
Type : Azepane, Carbamate, Benzodiazepin, Diazepan
Chemical_Nomenclature : 9-Methyl-3,9-diazatricyclo[8.4.0.03,7]tetradeca-1(14),10,12-trien-13-yl heptylcarbamate
Canonical SMILES : N1(CC3N(CC2=CC(=CC=C12)OC(NCCCCCCC)=O)CCC3)C
InChI : InChI=1S\/C21H33N3O2\/c1-3-4-5-6-7-12-22-21(25)26-19-10-11-20-17(14-19)15-24-13-8-9-18(24)16-23(20)2\/h10-11,14,18H,3-9,12-13,15-16H2,1-2H3,(H,22,25)
InChIKey : FGHLTEARVUTWCN-UHFFFAOYSA-N
Other name(s) :
Target
Families : Diazepine-carbamate-cpd6b ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Novel diazepine-carbamate derivatives as dual-acting butyrylcholinesterase inhibitors and antioxidants for Alzheimers disease - Al-Rifai_2025_Med.Chem.Res__ |
| Author(s) : Al-Rifai N , Amro R , Zahra JA , Darras F , Taha MO |
| Ref : Med Chem Res , : , 2025 |
| Abstract : |
| PubMedSearch : Al-Rifai_2025_Med.Chem.Res__ |
| PubMedID: |