Benzodiazepin
General
Benzodiazepine is the fusion of a benzene ring and a diazepine ring. Drugs which lower brain activity (diazepam Valium) enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABAA receptor. Not A/B hydrolase targets but some prodrugs are substrates of esterases
| Inhibitor | Main targeted enzyme families | Type | Structure |
|---|---|---|---|
| Diazepine-carbamate-cpd6b | BCHE | Azepane Carbamate Benzodiazepin Diazepan |
|
| JM-20 | ACHE | Benzodiazepin Not AlphaBeta Hydrolase target Pyridine Multitarget 2-nitrophenyl Azepane |
|
| W22 | Bacterial_esterase | Benzodiazepin Diazepan Azepane |
|