Donepezil-caffeic-acid-DP-CA
General
Type : Derivative of Donepezil, Hydroxycinnamic-ester, Cinnamate, Piperidine
Chemical_Nomenclature : 2-({1-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enoyl]piperidin-4-yl}methyl)-5,6-dimethoxyindan-1-one
Canonical SMILES : N1(CCC(CC1)CC3CC2=CC(=C(C=C2C3=O)OC)OC)C(C=CC4=CC(=C(C=C4)OC)OC)=O
InChI : InChI=1S\/C28H33NO6\/c1-32-23-7-5-18(14-24(23)33-2)6-8-27(30)29-11-9-19(10-12-29)13-21-15-20-16-25(34-3)26(35-4)17-22(20)28(21)31\/h5-8,14,16-17,19,21H,9-13,15H2,1-4H3
InChIKey : NWTRSUOFBYVQLQ-UHFFFAOYSA-N
Other name(s) : DP-CA || 2-({1-[(E)-3-(3,4-Dimethoxyphenyl)acryloyl]-4-piperidyl}methyl)-5,6-dimethoxy-1-indanone
Target
Families : Donepezil-caffeic-acid-DP-CA ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : A Novel Donepezil-Caffeic Acid Hybrid: Synthesis, Biological Evaluation, and Molecular Docking Studies - Kilicaslan_2023_Biochemistry.(Mosc)_88_50 |
| Author(s) : Kilicaslan D , Kurt AH , Kose M , Cesme M , Gungor O , Oztabag CK , Doganer A |
| Ref : Biochemistry (Mosc) , 88 :50 , 2023 |
| Abstract : |
| PubMedSearch : Kilicaslan_2023_Biochemistry.(Mosc)_88_50 |
| PubMedID: 37068881 |