Reactivators of organophosphate-inhibited ChEs give rise to phosphorylated oximes that reinhibit the enzyme. Reactivation of AChE inhibited by MEPQ with TMB4 will give EMP-TMB4
Type : Organophosphate, Phosphonylated oxime
Chemical_Nomenclature : ethoxyl methylphosphonyl-TMB4
Canonical SMILES : C1=[N+](C=CC(=C1)C(=NO)[H])CCC[N+]2=CC=C(C=C2)C(=NC[P](C)(OCC)=O)[H]
InChI : InChI=1S\/C19H26N4O3P\/c1-3-26-27(2,25)17-20-15-18-5-11-22(12-6-18)9-4-10-23-13-7-19(8-14-23)16-21-24\/h5-8,11-16H,3-4,9-10,17H2,1-2H3\/q+1\/p+1
InChIKey : DDIUMVSLOCHNNG-UHFFFAOYSA-O
Other name(s) : ethoxy methyl phosphonyl TMB-4, EMP-Trimedoxime
Families : EMP-TMB4 ligand of proteins in family
ACHE