ESP4
ESP4 BChE IC50 = 71.78 +/- 1.90 nM
General
Type : Piperidine, Naphthalen, Carboxamide, Fluorescent Probe, Phenalen
Chemical_Nomenclature : N-[(1-{4-[6-(dimethylamino)-1,3-dioxo-2-aza-3H-phenalen-2(1H)-yl]butyl}piperidin-3-yl)methyl]-N-2-(dimethylamino)ethyl-naphthalene-2-carboxamide
Canonical SMILES : O=C(N(CC4CN(CCCCN3C(C2=C1C(=CC=C(C1=CC=C2)N(C)C)C3=O)=O)CCC4)CCN(C)C)C5=CC6=C(C=C5)C=CC=C6
InChI : InChI=1S\/C39H47N5O3\/c1-40(2)23-24-43(37(45)31-17-16-29-12-5-6-13-30(29)25-31)27-28-11-10-21-42(26-28)20-7-8-22-44-38(46)33-15-9-14-32-35(41(3)4)19-18-34(36(32)33)39(44)47\/h5-6,9,12-19,25,28H,7-8,10-11,20-24,26-27H2,1-4H3
InChIKey : YIDBCXQRGLWCRW-UHFFFAOYSA-N
Other name(s) : N-[(1-{4-[6-(Dimethylamino)-1,3-dioxo-2-aza-2,3-dihydro-1H-phenalen-2-yl]butyl}-3-piperidyl)methyl]-N-2-(dimethylamino)ethyl-2-naphthamide
Target
Families : ESP4 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Rational design of environment-sensitive fluorescent probes for butyrylcholinesterase and their application in biological imaging - Shao_2026_Anal.Methods__ |
| Author(s) : Shao L , Wang F , Wang Y , Du J , Cao W , Zhang Q , Zhao F , Wang J , Fan W , Zhou Y , Wang B , Pang X , Yan L |
| Ref : Anal Methods , : , 2026 |
| Abstract : |
| PubMedSearch : Shao_2026_Anal.Methods__ |
| PubMedID: 41944317 |