Ethylpiperidinyl-ethyl-indole-Cpd19
isolated from aerial parts of Vinca minor L. (Apocynaceae(small periwinkle, petite pervenche) HBChE IC(50) of 0.65 +/- 0.16 microM
General
Type : Indole, Piperidine, Natural
Chemical_Nomenclature : (-)-2-ethyl-3[2-(3-ethylpiperidinyl)-ethyl]-1H-indole
Canonical SMILES : C2(C1=CC=CC=C1NC2CC)CCN3C[C@H](CCC3)CC
InChI : InChI=1S\/C19H30N2\/c1-3-15-8-7-12-21(14-15)13-11-17-16-9-5-6-10-19(16)20-18(17)4-2\/h5-6,9-10,15,17-18,20H,3-4,7-8,11-14H2,1-2H3\/t15-,17?,18?\/m0\/s1
InChIKey : YMVGBSPHIRQGFV-ZLPCBKJTSA-N
Other name(s) :
Target
Families : Ethylpiperidinyl-ethyl-indole-Cpd19 ligand of proteins in family
BCHE
Protein :
human-BCHE
References (1)
| Title : Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease - Vrabec_2021_Phytochemistry_194_113017 |
| Author(s) : Vrabec R , Marikova J , Locarek M , Korabecny J , Hulcova D , Hosalkova A , Kunes J , Chlebek J , Kucera T , Hrabinova M , Jun D , Soukup O , Andrisano V , Jenco J , Safratova M , Novakova L , Opletal L , Cahlikova L |
| Ref : Phytochemistry , 194 :113017 , 2021 |
| Abstract : |
| PubMedSearch : Vrabec_2021_Phytochemistry_194_113017 |
| PubMedID: 34798410 |